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S Burtey

Publications and source records attributed to S Burtey.

9 recordsLinked to original sources

Ancestrally-duplicated paraHOX gene clusters in humans.

A paraHox gene cluster has been described recently in Amphioxus. We show here using bioinformatics and cytogenetics that, as the probable result of the duplication of an ancestral paraHox gene cluster, human paraHOX genes are located in four paralogous regions of the genome, on chromosomes 4, 5, 13 and X. By analogy with the four HOX gene clusters, we propose to designate the four paraHOX gene clusters as paraHOX-A to D clusters. We also propose a scenario for the evolution of HOX and paraHOX genes. Several chromosomal translocation breakpoints of hemopathies are located in the paralogous regions that contain the paraHOX genes. Two of the paraHOX genes are involved in these rearrangements.

Amino Acid Sequence↗

Glomerulonephritis.

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Glomerulonephritis↗

[Cycloid psychoses].

Cycloid psychoses constitute an original classification originally proposed by Leonhard and comprising clinical pictures intermediate between schizophrenic psychoses and bipolar disorders. The exact situation of these disorders in psychiatric classifications has been the subject of debate, and their existence is still questioned. Only schizo-affective psychoses have been accepted as autonomous. Treatment of cycloid psychoses most often consists of neuroleptics but also mood regulators, particularly those having anti-epileptic effects Lastly, prognosis of these disorders usually is not as poor as that of schizophrenia and is marked by a cycloid course, with symptom-free periods between episodes.

Humans↗

[Tubular necrosis after non-steroidal anti-inflammatory agents and acute alcoholic intoxication].

Acute nephrotoxicity due to nonsteroidal anti-inflammatory drugs is usually observed in clinical situations in which renal perfusion is compromised as in volume contraction. We report a case of a 20 year-old woman who suffered from acute tubular necrosis after concomitant ingestion of nonsteroidal anti-inflammatory drugs and binge drinking. This acute tubular necrosis is likely to have an hemodynamic origin due to nonsteroidal anti-inflammatory drugs in a patient with volume contraction secondary to binge drinking. The risk appears to be even more important since ethanol has been implicated in tubular necrosis by direct toxicity. This observation underlines the danger in associating nonsteroidal anti-inflammatory drugs and ethanol.

Acute Kidney Injury↗

[Sweet's syndrome and aseptic abscess of the spleen].

Extra-cutaneous manifestations of neutrophilic dermatosis are exceptional and diverse: they consist of inflammatory infiltrates with neutrophil polymorphonuclears, without evidence of infectious agents. Localisations to the lung are the most frequently observed. A single observation of spleen involvement has been reported in a case of Sneddon-Wilkinson's disease. Herein we report the case of an aseptic splenic abscess during the course of a Sweet's syndrome.

Abscess↗