Biomedical subjects
Publications and source records attributed to S C Edminster.
The case of a 28-year-old multiparous woman with an incarcerated gravid uterus is presented. This largely unknown entity invariably results in spontaneous abortion if untreated. Patients present with a characteristic and readily recognizable sign and symptom complex and ultrasonographic findings. Early diagnosis is emphasized and therapy is outlined.
Gasoline is a readily obtainable intoxicant that unfortunately lends itself to habitual abuse by sniffing, a practice found particularly among children and adolescents. The concerted effects of the multiple hydrocarbon and other constituents of gasoline result in a predictable acute toxic syndrome. Organoleads, primarily tetraethyl lead (TEL), cause a separate toxicologic symptom-sign complex that overlaps with the initial acute toxic syndrome. The different clinical symptomatology, effects on hemoglobin synthesis, and response to chelation therapy are all in keeping with the view that organolead poisoning is a separate and distinct toxicologic entity from that of classical elemental lead poisoning or "plumbism".
We describe a logical and systematic approach to unknown dermatologic disease entities that utilizes a simple algorithm which, when properly applied, expeditiously narrows the differential diagnosis and provides a key to standard reference books. We find this algorithm system to be superior to the common and often frustrating exercise of leafing through the dermatologic atlas in search of a picture that matches the presenting rash.