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Biomedical subjects

S C Higgs

Publications and source records attributed to S C Higgs.

8 recordsLinked to original sources
PubMed1977

The perinatal infective environment and infants of very low birth weight.

Evidence of an infective environment was frequently found in infants weighing less than 1 500 g at birth. Bacterial cultures from multiple sites bore no correlation to pus cells in the gastric aspirate or to placental histology. Positive cultures of ear swabs correlated with mortality, as did placental infection. The presence of pus cells in the gastric aspirate was related to histological evidence of placental infection. The duration or rupture of membranes and the serum IgM levels were not significantly associated with other findings.

Bacteria↗
PubMed1977

A study of the plasma free amino acids in infants of low birth weight, with a comparison of oral feeding with milk and total parenteral nutrition.

The plasma amino acid concentrations soon after birth, at 10 days and 1 month, were estimated in 25 infants of low birth weight (less than 1 500 g). Ten of these infants were fed with amino acids as casein hydrolysate, through the umbilical artery for the first 10 days. The normal range of plasma amino acid values for infants of low birth weight shows a wider range of concentrations than that of term infants. During total parenteral nutrition (TPN) the plasma amino acid values were generally elevated above those obtained in infants receiving conventional feeding with a "humanised" milk formula. In particular, the concentrations of aspartic acid, phenylalanine, cystine, leucine, isoleucine and glutamic acid were significantly higher. With the cessation of TPN, these levels returned to normal, so that no significant difference could be detected between the 2 groups after 1 month. The suitability of current amino acid solutions for paediatric use is discussed.

Amino Acids↗
PubMed1976

Infants of very low birthweight: a follow-up study.

The survival, growth and neurodevelopmental status of a group of non-White infants of very low birthweight, who were managed in the Neonatal Intensive Care Unit of Groote Schuur Hospital, is reported. The effect of certain high-risk perinatal factors on this status is assessed.

Birth Weight↗
PubMed1975

Gestational age assessment in infants of very low birthweight.

The accuracy of gestational age assessment (Dubowitz et al., 1970) was tested for infants weighing 1500 g or less. There was good correlation with known dates. This system is applicable to and accurate for infants delivered very prematurely.

Birth Weight↗