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Biomedical subjects

S C Mittal

Publications and source records attributed to S C Mittal.

7 recordsLinked to original sources
PubMed1987

Childbirth following primary cesarean section--evaluation of a scoring system.

Of 1184 cases with previous cesarean section, 590 were selected for trial of vaginal delivery and 594 for repeat cesarean section. Of the former group, 76.6% had successful vaginal delivery. Incidence of uterine wound dehiscence and of perinatal mortality was highest in cases with primary classical cesarean section. Factors like indications for previous cesarean section, history of intercurrent vaginal delivery, weight of baby and period of gestation had positive correlation with delivery outcome.

Cesarean Section↗
PubMed1987

Evaluation of preinduction scoring systems.

Two hundred patients requiring induction of labour were assigned a preinduction score according to Dhall's criteria and Bishop's criteria. A score of 9 or more (Dhall) and 6 or more (Bishop) had favourable outcomes with successful induction in more than 90% of patients and an induction delivery interval (IDI) of less than 12 hours. In multiparas a Dhall score of more than 7 had a sensitivity and specificity of 88.6% and 90.0% respectively in predicting induction outcome compared to Bishop score sensitivity of 86.3% and low specificity of 47.4%. Correlation of the score with IDI as a dependent variable also showed that the Dhall score had a better predictive value than the Bishop score.

Cesarean Section↗
PubMed1987

Studies on sister chromatid exchange (SCE) induction by gamma-irradiation and protective effect of L-cysteine in HeLa cells.

Effect of different doses of gamma-irradiation on SCE induction in unifiliarly 5-bromo 2-deoxyuridine substituted DNA was studied in various phases of cell cycle. Changes in gamma-irradiation induced SCE frequency was measured by post-irradiation treatment with antimutagen L-cysteine. Perturbation in cellular proliferation kinetics due to gamma-irradiation and gamma-irradiation plus L-cysteine was also studied. It was observed that gamma-irradiation is an efficient inducer of SCE and is most effective in S phase. L-cysteine also causes SCE induction which is slightly higher than the spontaneous level of SCEs found in HeLa cells. However, post-irradiation addition of L-cysteine reduces SCE frequency in gamma-irradiated cultures and this reduction is maximum in G1 phase irradiated cells. gamma-irradiation delayed the mitosis considerably and this delay continued to increase with increasing doses. L-cysteine reduced the delay in cell cycle caused by gamma-irradiation.

Cysteine↗
PubMedDate not supplied

Serum lipids, platelets, and fibrinolytic activity in cerebrovascular disease.

Fifty patients with occlusive cerebrovascular disease (ischemic thrombotic cerebrovascular disease--ITCBVC) were studied for clinical features, angiographic findings, serum lipids, platelet functions and fibrinolytic activity. Angiograms were abnormal in 24 of 36 cases. Two-thirds of these had an abnormality of the internal carotid artery in the neck; one-third had occlusion of the middle and/or anterior cerebral arteries. A statistically significant rise of serum triglycerides, pre-beta lipoproteins, platelet adhesiveness and aggregation, and a decrease in fibrinolytic activity were noticed in these patients as compared to age and sex matched controls. The correlation coefficient did not show any intercorrelation between the platelet adhesiveness and raised lipid fractions. These factors could be responsible for the atheroma resulting in large vessel occlusion.

Adult↗