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Biomedical subjects

S Camara

Publications and source records attributed to S Camara.

12 recordsLinked to original sources
PubMed2004

[Electrocardiographic recording of long duration (Holter) of 24 hours during idiopathic cardiomyopathy of the peripartum].

The idiopathic myocardiopathy of the peripartum (IMPP) is a frequent disease in the Soudano-Sahelian zone of Africa whose evolution is loaded with many complications hemodynamic, thrombo-embolic and rhythmic. The prevalence and the meaning of the rhythm disorders are unknown. The aims of this prospective study are to measure and to describe the prevalence of the anomalies observed in Holter ECG of 24 hours. It's about a description cross-sectional study realized at the Cardiology Department (CHU Dakar) and 19 patients with IMPP were included, from October 2000 to July 2002. A recording ECG of 24 hours (Holter) was realized on all the patients. The average age was 29.4+/-6.9 years with a low socio-economic level (100%). The diagnosis of IMPP done before childbirth in 4 cases (21%) and the post partum on 15 patients (78.9%). The dyspnea was constant, the chest pain in 12 cases (63.1%) and palpitations in 8 cases (42%). The average rate of hemoglobin was of 10.85+/-2.05 g/dL. The standard electrocardiogram recorded a sinusal tachycardia (68.4%), a cavitary hypertrophy (78.8%), and disorders of the repolarization (47.3%). The cardiac echo-Doppler noted a cavitary dilatation (84.2%), a constant alteration of the left ventricular systolic function with a fraction of average ejection of 29.7+/-10.3%. The anatomy of the valves was normal. The recording Holter ECG of 24 hours recorded a sinusal tachycardia in 17 cases (89.4%), ventricular extrasystoles on 7 patients (36.8%), 4 cases of ventricular tachycardia non-sustained and double ventricular extrasystole on 1 patient, auricular extrasystoles in 4 cases (21%) and 1 case of auriculo-ventricular block of the first degree. The study of heart rate variability founded a mean value of 106 ms.

Adult↗
PubMed2004

[Wilson's disease: study of 6 neurologic forms observed at the University Hospital in Conakry].

This report describes 6 cases of Wilson's disease observed at the University Hospital Center in Conakry, Guinea. Presenting symptoms involved extrapyramidal syndrome in 4 cases, psychomotor epilepsy in 1, and confusional syndrome in 1 case. Diagnosis was based on neuropsychic manifestations, Kayser-Fleicher corneal ring, liver failure, and impaired copper metabolism. Brain CT-scan depicted normal features in 3 cases, symmetric hypodensity of the lenticular nucleus in one, discrete ventricular dilatation of in one a and cortico-subcoetical atrophy in one.

Adolescent↗
PubMed1991

Effects of dipyridamole on the short-term evolution of glomerulonephritis.

The aim of the present study is to evaluate the effect of dipyridamole (300 mg/day) versus placebo in a double-blind randomized trial on membranous glomerulonephritis (M-GMN), mesangial IgA glomerulonephritis (IgA-GMN), and segmentary and focal hyalinosis glomerulonephritis (SFH-GMN) during the first 3 months of treatment. In the case of M-GMN, proteinuria dropped by 60% of the basal value in patients treated with dipyridamole; in the case of IgA-GMN it dropped by 65-70%; and in the case of SFH-GMN it dropped by 40% of the basal value. Inhibition of proteinuria in M-GMN was correlated to platelet response, and above all, to the ADP-induced platelet aggregation in whole blood.

Dipyridamole↗
PubMed1988

[Mycetoma of the fingers. Apropos of 5 case reports].

The authors report 5 cases of mycetomas of the fingers observed over a period of 5 years in a series of 18 mycetomas of the hand. In 3 cases, the lesion only involved the soft tissues, which were excised with 2 apparent cures after 2 and 5 years and one recurrence. In the other 2 cases, the bone was invaded and 2 digital amputations were performed without recurrence after 2 and 6 years. The authors review the epidemiology and histopathology of this disease as well as the absence of any truly effective medical treatment. In the presence of bone invasion, only excision can ensure cure.

Adult↗
PubMed1987

Platelet aggregation in human whole blood after chronic administration of aspirin.

We have used the impedance aggregometer to study the "ex vivo" effect of acetylsalicylic acid (ASA) in whole blood (WB) versus platelet-rich plasma (PRP) in 35 male healthy volunteers after 10 days of treatment with 25, 50, 125, 250, and 500 mg/day of ASA. Percent of inhibition of platelet aggregation was determinated at the end of treatment. A greater inhibition of platelet aggregation was observed in WB than in PRP when ASA was administrated at almost all doses. Maximal differences were at 25, 50, and 125 mg/day of ASA on adrenaline, collagen and arachidonic acid induced aggregation, and with 250 and 500 mg/day of ASA when ADP was used as aggregating agent. In the "in vitro" trials, IC-50 values of ASA on ADP and collagen induced aggregation were determined in platelet aggregation by the impedance method in both WB and PRP. ASA shows a lower IC-50 in WB than in PRP. When leucocytes were incubated in PRP samples, it effect was similar to the percent of inhibition in WB.

Adenosine Diphosphate↗
PubMed1986

Effects of acetylsalicylic acid on platelet aggregation in male and female whole blood: an in vitro study.

We have used the impedance aggregometer to study the in vitro effect of acetylsalicylic acid (ASA) in whole blood (WB) versus platelet-rich plasma (PRP) using blood samples from 24 male and 24 female healthy volunteers. IC50 was calculated from dose-response curves of ADP-, adrenaline-, collagen- and arachidonic acid-induced aggregation. ASA inhibited platelet aggregation in WB with a lower IC50 than PRP in male and female samples; the greater differences between WB and PRP inhibitory effect of ASA were in collagen- and archidonic acid-induced aggregation. A higher ASA concentration was needed in order to produce half maximal inhibition of platelet aggregation in female than in male samples with both WB and PRP method, except when ADP was used as the aggregating agent in PRP.

Adenosine Diphosphate↗
PubMedDate not supplied

Pathological and immunohistochemical study of the abomasum and abomasal lymph nodes in goats experimentally infected with Haemonchus contortus.

Histopathological changes and the distributions of T and B lymphocytes and IgG producing plasma cells were recorded in the abomasum and abomasal lymph nodes of goats 3, 7 and 21 weeks post-infection (wpi) after an experimental infection with H. contortus. The low rate of worm recovery by 3 wpi (5.6%) might have been due to larvae death as suggested by the presence of granulomas in the abomasal mucosa at 3 and 7 wpi, or simply due to a poor larval establishment. Marked increase in the secretion of mucus by mucous cells together with an abundant infiltration of eosinophils, mast cells, CD3+ T lymphocytes, CD79a+ B cells, IgG+ plasma cells and globule leukocytes were recorded in the abomasal mucosa, especially at 7 wpi. Except for the globule leukocytes, this reaction decreased substantially by week 21, suggesting this cell type may have been involved in rejection of adult nematodes. The abomasal lymph nodes showed marked hyperplasia, particularly of CD79a+ B cells and IgG+ plasma cells in all infected goats. These reactions may have been responsible for the reduction in the number of worms found in the abomasum between 3 and 7 wpi.

Abomasum↗
PubMedDate not supplied

[Neurotraumatic emergencies at the University Hospital Center in Dakar. Apropos of 120 injuries of the cervical spine].

In Senegal, traumas of spinal column are characterized not only by their high frequency and their etiology, but also and mainly by the extreme severity of their neurological lesions. A review of 120 traumas of cervical spine revealed: The importance of the neurological lesions (75%). The influence of the factors of severity and of the treatment. Global mortality rate of 35% raises to 46.46%, consequent on neurological lesion and to 85.71% consequent on total tetraplegia.

Cervical Vertebrae↗
PubMedDate not supplied

[Human activities, hydro-agricultural management and urinary schistosomiasis. Methodological approach and results (a preliminary study in Upper-Volta)].

In the schistosomiasis endemic sub-sahelian region, a study of the prevalence of the disease was carried out on three different areas: the highest was around a small river, the lowest in the hydro-agricultural management region, mean prevalence was noted around a natural lake. Human activities have been classified with regards to the areas of transmission. Activity is closely linked to prevalence. For the populations, symptoms of urinary schistosomiasis (Rudzenga) constitute a real disease, traditional healers are the masters of earth (Tengsoba), water has hardly any importance in transmission.

Adolescent↗
PubMedDate not supplied

[Mortality caused by traffic accidents at the Traumatology and Orthopedics Center of Grand-Yoff. A 2-year study. Apropos of 156 cases].

Most of road accident casualties are directed to the "Centre de Traumatologie et d'Orthopedie" between March 1989 and March 1991, the emergency Department received 8250 casualties treated by a team core comprising anesthetist-intensive care doctors and orthopaedic surgeons supplemented when necessary by other specialists. Out of those 8250 casualties aged 30 in average, 156 died at the hospital in varying time limits. The authors of present study intend to assess the efficiency of the medical and surgical care provided to identify the most frequent death causes and to suggest ways means of reducing the death toll. Forensic autopsies revealed the following lesions by order of prevalence: brain traumas 68, polytraumatisms 58, cervical vertebral traumas 13, abdomen traumas 7, polyfractures 3. In despite of the working conditions improvement at this specialized center (intensive care, technical facilities and staff) the mortality rate remains high, specially in polytraumatisms and brain traumas. The authors insist upon the need for a medically assisted transport unit which would take care of casualties before their arrival at hospital and for the acquisition of modern diagnosis means (tomodensitometry).

Abdominal Injuries↗