PubMed Health⌕ Search

Biomedical subjects

S Carranza Lira

Publications and source records attributed to S Carranza Lira.

At least 19 recordsLinked to original sources
PubMed2000

[Changes in pituitary gonadotropins according to body mass index and adipose tissue distribution, in postmenopausal women receiving different types of hormone replacement therapy].

OBJECTIVE: To establish how gonadotrophins levels are modified according to body mass index (BMI) and waist-hip ratio (WHR), in postmenopausal women receiving different types of hormone replacement therapy (HRT). METHOD: Forty postmenopausal women were studied, and divided into two groups of 20 women each one (according to the HRT schedule administered (continuous or continuous combined). At baseline, three and six months, luteinizing hormone (Lh), follicle stimulating hormone (FSH) and estradiol (E2) serum levels were determined. The two groups were divided into two subgroups first according to BMI, and thereinafter according to WHR. Differences among the groups were assessed by Mann-Whitney U test. The changes along each treatment group, were determined by Wilcoxon test. RESULTS: FSH and LH levels decreased and those of E2 increased at 3 and 6 months after the beginning of treatment in each one of the HRT schedules, but without differences among them. Upon subdividing the groups, the changes were similar to the undivided group. CONCLUSIONS: It can be concluded that HRT modifies pituitary gonadotrophin secretion, but later changes exist in LH in obese and those with upper level body fat distribution.

Adipose Tissue↗
PubMed2000

[Usefulness of the relationship between follicular stimulating hormone, deoxypyridinoline, estradiol, and inhibin as decision criterion for starting replacement hormone therapy in climacteric and its correlation with symptomatology].

INTRODUCTION: There is no precise indication for the adequate moment to start hormone replacement therapy (HRT). OBJECTIVE: To evaluate several indexes obtained with serum levels of follicle stimulating hormone (FSH), estradiol (E2), estrone (E) and inhibin and urinary deoxypyridinoline (DPD) and correlate them with Kupperman index as decision criteria for the beginning of hormone replacement therapy (HRT) in the climatery. MATERIAL AND METHODS: In 53 patients the presence and intensity of climateric symptoms was evaluated using the modified Kupperman's index. They were divided in: premenopausal, perimenopausal or postmenopausal. groups FSH, E2, E and inhibin blood levels, as well as urinary DPD were measured. Several indexes were calculated, and then were compared between the groups and correlated with Kupperman's index score. Statistical analysis. Kruskall-Wallis and Mann-Whitney U test were done, as well as Spearman's correlation analysis. RESULTS: After comparing the indexes, the Log FSH/E2, Log FSH/E2, Log FSH/E2/E, Log FSH(DPD)/E2, Log FSH(DPD)/E2/E and Log FSH (DPD)/Inhibin(E2) were significantly greater in postmenopausal group. Only there was a significant correlation between Log FSH/Inhibin(E2) index, and Log FSH(DPD)/Inhibin(E2) index with Kupperman's index. CONCLUSIONS: Log FSH (DPD)/E2/E index seems to be the more suitable, index because it had a progressive increase as the patients advanced towards postmenopause. The afore mentioned index must be validated with a greater number of patients to assess a cut point that can define in which patients HRT must be administered.

Adult↗
PubMed2000

[Determination of the sensitivity and specificity of an osteoporosis risk factor questionnaire].

OBJECTIVE: To determine de sensitivity and specificity of a questionnaire of osteoporosis risk factors. MATERIAL AND METHODS: In 1,088 files of postmenopausal women, osteoporosis risk factors such as age, time since menopause, former hormone replacement therapy (HRT) use, current use of HRT, former and current HRT use, fractures after 45 years age, actual weight, corticosteroid use and hyperthyroidism were analyzed, giving them different punctuation. Every punctuation was added in each patient. In all of them a dual emission X ray (DEXA) absorptiometry was done from lumbar column and hip (femoral neck, trochanter and Ward's triangle). Odds ratio, sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) were calculated for every one of the variables and DEXA T score as well as Spearman correlation coefficient. RESULTS: Odds ratio increased as the punctuation of the questionnaire increased. With four points in the questionnaire the PPV was 41%, the NPV 86%, the sensitivity 16% and the specificity 96%. A significant negative correlation was found between age, time since menopause, current use of HRT, former and current use of HRT and column and hip T scores, and with the punctuation for all the regions. A positive correlation was found between former fracture and column and femoral neck T scores, and with actual weight in all regions. CONCLUSIONS: This study showed that the questionnaire can be a useful instrument to identify patients at high risk of osteoporosis.

Absorptiometry, Photon↗
PubMed2000

[Evaluation of the risk of osteoporosis in postmenopausal patients in the Hospital Luis Castelazo Ayala of the Mexican Social Security Institute, using a risk factor questionnaire].

Osteoporosis has a great impact on the population due to economic and health implications. For these reasons there is great interest to find the best prevention, diagnosis and treatment criteria. Postmenopausal women are at increased risk due to estrogen deficiency that is present in this stage of life. Through an oral interview the risk of osteoporosis in postmenopausal women was evaluated. The questionnaire was applied to 150 postmenopausal patients, questioning age, ethnic group, history of rheumatoid arthritis, use of estrogenic replacement therapy and body weight. Osteoporosis risk considered when a punctuation of 6 or greater. It was found that 85 of the patients had a punctuation of 6 or greater, with a mean punctuation of 7.5, indicating the risk of osteoporosis in our population. The most important factors that increased the punctuation and the risk to present osteoporosis were body weight and the lack of estrogen replacement therapy. We consider that these kind of questionnaires may be useful to detect the population at risk for osteoporosis and in base to this the adequate exams for diagnosis must be ordered.

Body Weight↗
PubMed1999

[Changes in body weight and the distribution of adipose tissue in hysterectomized postmenopausal patients on estrogen replacement therapy].

The purpose was to look how the weight and body fat distribution is modified after estrogen replacement therapy (ERT). 52 patients older 40 years age, hysterectomized and with bilateral salpingo-oophorectomy were studied. They were divided in two groups: I) received ERT with conjugated equine estrogens 0.625 mg daily (n = 35) and II) with no ERT (n = 27) (control). Every three months corporal weight, body mass index (BMI) and waist-hip ratio was measured for a 12-month period. With the exception of the control group, which was only studied for three months. In the ERT group the corporal weight and the BMI significantly increased at six months (p < 0.01 y p < 0.006, respectively), without changes in the other parameters. The control group had no significant changes in the analyzed parameters during the study time. When the group with ERT was compared with the control group at third month, there was a significant increase in weight (p < 0.05) in the control group. Without any differences in the other analyzed variables between the groups. It was not possible to demonstrate that corporal weight and body fat distribution were permanently modified in those patients with ERT. These data agree with recent reports in which no changes have been detected with hormone replacement therapy usage.

Adipose Tissue↗
PubMed1999

[Vaginal reconstruction].

This article review the congenital vaginal absence, as well as the evolution of the different techniques to construct a neo vagina. Also the advantages and disadvantages of the most used actual techniques are discussed.

Female↗
PubMed1994

[Hysteroscopic myomectomy. Surgical management. Presentation of a case].

A case of a 34 years old woman with primary sterility secondary to multiple myomatosis, is presented. Any other sterility factor was ruled out. First, she went on laparotomy for multiple myoma resection but two of these were left. The cornual myoma couldn't be removed because the high risk of salpinx damage. The other one was a 3 cm. intracavitary tumor. After four months on leuprolide acetate therapy an hysteroscopic myomectomy was performed. The next menstrual cycle pregnancy was achieved.

Adult↗
PubMed1994

[The evaluation of the usefulness of ultrasound independent of estradiol as a prognostic criterion for ovular capture and maturity. A comparative double-blind study].

One hundred and twenty women were studied which had primary or secondary sterility, and underwent into the GIFT or IVF-ET program at the INPer. They were divided in two groups. Group I had 96 women in which only was taken in account the follicular development measured by vaginal ultrasound to decide continuation or cancellation, in this group estradiol serum levels determination was done, but it was not used for decision making; group II had 24 women in which estradiol was taken in account in addition with ultrasound. There were no differences in the number of follicles seen by ultrasound neither in the estradiol serum levels between the groups. Correlation coefficients between follicles seen by ultrasound and retrieved oocytes and mature oocytes, thus partial correlation coefficients for follicles seen by ultrasound plus estradiol serum levels and retrieved oocytes and captured oocytes were higher in group I in all days with the exception of day 10 in which they were similar. By the aforementioned in can be concluded that in this group of patients the ultrasound was the most reliable variable to give a quantitative and qualitative prognostic of oocyte retrieval.

Adolescent↗
PubMed1994

[The ovarian hyperstimulation syndrome. Institutional experience].

Thirty patients with OHS were analyzed; all of them had to be hospitalized. There was no difference as to sterility time and syndrome appearance. The use of menotropines caused more frequently the syndrome. There was multiple pregnancy in 33%. Abortion incidence was 16%. As the etiology is unknown there is not an adequate treatment, and care is for maintenance. Prevention is the best option.

Adult↗
PubMed1994

[Pregnancy after a partial dearterialization of the uterus. A case report].

A case of a 27-year-old woman with a previous partial uterine dearterialization for uterine atony in its first gestation, is presented. This woman asked advise for secondary infertility and after a laparoscopic adhesiolysis she achieved pregnancy. With the exception of tubo-peritoneal factor all other infertility studied factors were normal. Partial uterine dearterialization must be taken in account in patients with obstetric bleeding and posterior fertility expectatives.

Adult↗
PubMed1994

[Obstetrical analysis of pregnancies obtained by GIFT or FIV at the National Institute of Perinatology].

The obstetrical outcome of 47 pregnancies which was achieved by assisted reproduction techniques was analyzed. 38 were achieved by GIFT and 9 by IVF-ET. In both series we found that the analyzed parameters are similar to those described by other groups. But in discordance with Angle-Saxon groups, in Latino-American series the principal delivery way was by cesarean section.

Apgar Score↗
PubMed1994

[The laparoscopic findings in patients with chronic pelvic pain and dysmenorrhea].

Forty-nine laparoscopic findings of women with chronic pelvic pain and dysmenorrhea, were reviewed. In all of them a laparoscopy was performed under general anesthesia. Endometriosis was found as principal cause of the pain, followed by chronic pelvic inflammatory disease and adhesions. In 10.2% of the patients the pelvis was normal. We can conclude that in the patient with chronic pelvic pain, laparoscopy is a useful method to achieve the correct diagnosis to prescribe the most accurate treatment.

Adult↗
PubMed1993

[The effect of the early administration of progesterone on egg recovery, fertilization and pregnancy in an institutional fertilization in vitro program].

39 patients which underwent an IVF-ET procedure at the INPer were divided in two groups. To one of them, progesterone was administered since the day of oocyte retrieval (group I), whereas the other group received progesterone 48 hours before hCG administration (group II). There were no statistical differences between the groups in the parameters analysed before the oocyte retrieval. There were statistical differences between the groups in progesterone levels in the day of oocyte retrieval in favour of group II, and in fertilization rate and transfer rate for group I. There were no valuable differences between the groups in pregnancy rate.

Adolescent↗
PubMed1993

[Biological process in patients having been impregnated through GIFT or IVF-ET. Clinical experience].

There were analyzed in a retrospective way the results of pre-retrieval hormonal levels as well as the number of retrieved oocytes, mature oocytes and transferred embryos in three groups of patients (2 GIFT, 1 IVF-ET) which achieved a pregnancy, and were matched with groups with no pregnancy. There were no statistically significant differences in most of the analyzed parameters, by the aforementioned we can suppose that pregnancy depends of endometrial quality and in this moment we are not able to modify it satisfactorily.

Adult↗
PubMed1993

[Determination of gastrin levels in maternal and neonatal serum as well as in amniotic fluid in acute fetal distress].

The objective was to measure gastrin (G) levels in maternal and neonatal sera as well as in amniotic fluid in patients with fetal distress and a control group. Twenty-five patients with term pregnancies were assigned to the following two groups: fifteen with acute fetal distress and ten with previous cesarean section. Maternal and neonatal blood and amniotic fluid samples were taken at the time of delivery. Differences between groups were calculated with non-parametric Mann Whitneys' U test. A significant difference (p < 0.001) between G levels in amniotic fluid of fetal distress and those of the control group was found. In conclusion, serum G levels can be used as another predictor of fetal distress, although further studies must be performed before it can be used as a clinical tool.

Acute Disease↗
PubMed1993

[Correlation between estradiol concentrations and follicular measurements vs. oocyte maturity in three different ovarian stimulation schedules].

The responses to different ovarian stimulation schedules were studied in women which underwent in programs of assisted fertilization. The follicular development and seric estradiol with the number and quality of the retrieved oocytes. Were correlated 49 patients and divided in 3 groups according to ovarian stimulation schedule were analyzed. The stimulation was followed day by day with seric estradiol and ultrasound follicular measurement. With the three schedules were retrieved 205 oocytes, being mature 179, immature 9 and 17 atretic, there was no significant difference between the different schedules.

Clomiphene↗
PubMed1992

[Report of a case of deferred abortion in cervical pregnancy].

A patient with cervical pregnancy by clinical and ultrasonographic criteria underwent cervical and uterine curettage without complications. The histological study showed hyalinized corial villous with inflammatory infiltration and the material from uterine cavity showed decidual changes. The spontaneous and previous embryo death induce a scanty bleeding following curettage and thus, corroborate in a natural way the efficacy of any substance used to desvitalize the pregnancy and in consequence, diminish the vascular blood flow before evacuation in order to get a good result following conservative management.

Abortion, Induced↗