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S Cavalli

Publications and source records attributed to S Cavalli.

21 records · Page 2Linked to original sources

[Applied physiology: the work of driving an industrial heavy-duty truck on the highway].

Scope of this work was the investigation of the following parameters: energetic metabolism, by O2 consumption measurement using the open-circuit technique; pulmonary ventilation; cardio-circulatory activity behaviour, by recording heart rate, E.C.G., arterial blood pressure and plethysmography of lower limbs; body temperature pattern; visual function, through the determination of the visual field; kidney function through urine analysis; body joints flexibility, by proper test. The subjects chosen for this investigation are three experienced heavy-duty vehicle drivers that where submitted to proper checks before, during and after having driven a 190.38 Model truck fitted with spoiler and an S.R. Viber, high cargo body tarpaulin, PTT, 43.2 tons overall weight truck, over 9 different courses including town traffic, level highway, up and downhill highway with different gradients, in a period from 9 a.m. to 8 p.m. Along the total run of 404 kilometres, covered in 364 minutes, recording of the parameters under investigation was carried out over 249 kilometres covered 240 minutes (72% of overall driving time). Energy expenditure (1.20 +/- .19 Kcal/min at rest) resulted higher on steep uphill stretches with many bends (2.28 +/- .44 Kcal/min) than on less steep up- and downhill stretches and in city traffic (1.82 +/- .21 Kcal/min). The lowest energy expenditure--in some cases lower than the value found in the experimental rest--was recorded during motorway driving (1.28 +/- .19 Kcal/min). Pulmonary ventilation was characterized by frequent changes in rate and tidal air, in strict relationship with driving work bio-mechanical requirements (operation of the steering wheel). Also heart rate underwent ariations well in line with the energy expenditure pattern: of limited magnitude in uphill driving (+33% max over the value at rest), up to values identical with those at rest in the level highway drive. No appreciable variations were recorded in the respiratory quotient, calories/ventilation ratio and oxygen pulse. No significant changes occurred in arterial blood pressure, body temperature, auditory, visual and kidney functions, and in flexibility. Conversely, slight swelling (5%) of lower limbs was noticed at the end of the driving day. It was hence proven that--from the standpoint of energy expenditure--the work performed in driving a vehicle is not too exacting and does not induce particularly high nervous stresses. However, under given conditions, such as steady speed driving in level highway, a pre-sleep state occurs in all cases approximately after the first 30 minutes of driving, which in most cases the driver is not even aware of.(ABSTRACT TRUNCATED AT 400 WORDS)

Automobile Driving↗

Preparation, identification, and quantitative NMR determination of silyl derivatives of 6-aminopenicillanic acid, 7-amino-3-methyl-delta3-cephem-4-carboxylic acid, and 7-amino-3-acetoxymethyl-delta3-cephem-4-carboxylic acid.

A rapid and accurate method for the quantitative determination of the extent and ratio of amino and carboxyl group trimethylsilylation of 6-aminopenicillanic acid, 7-amino-3-methyl-delta3-cephem-4-carboxylic acid, and 7-amino-3-acetoxymethyl-delta3-cephem-4-carboxylic acid is presented. The method utilizes NMR spectroscopy and is based on the difference in chemical shifts between N-trimethylsilyl and O-trimethylsilyl groups or, in cephalosporin derivatives, between the methyl group in the 3-position and free amino resonances. The spectra of the N,O-bis(trimethylsilyl) derivatives are discussed.

Cephalosporins↗