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Biomedical subjects

S Celikić

Publications and source records attributed to S Celikić.

At least 19 recordsLinked to original sources

[Myocardial reinfarction].

A total number of 1924 patients were treated for acute myocardial infarction (AMI) at the Clinic for Urgent Medicine at the Military Medical Academy during the period of seven years (1991-1997). These myocardial infarctions were at different locations, the mean age of patients was 63.7 +/- 6.2, in male patients 1192 (61.9%) and 732 (38.1%) in female ones. Out of that number of patients, 406 (21.1%) had recurrent myocard infarction (RMI), 254 (62.6%) males and 152 (37.4%) females, of average age 64.8 +/- 8.3 years. Statistically, no significant differences were observed in those two groups of patients, concerning their age, location of myocardial infarction and administration of fibrinolytic therapy. There were, however, significant differences concerning the complications, primarily cardiac insufficiency, malignant arrhythmias, AV block II0 and III0, applications of temporary or permanent pacemaker and finally mortality. During intrahospital phase of treatment, in the first few months, obtained results revealed that the patients suffering from RMI had multiple and serious complications and that cardiac insufficiency was the main cause of high mortality rate in those patients.

Female↗

[Use of 99mTc-pyrophosphate and coronarography in the diagnosis of simultaneous myocardial infarct of the right and left cardiac ventricles].

Myocardial scintigraphy was performed using 99m-Tc-pyrophosphate in 50 patients with suspected coexisting right ventricular and left inferior ventricular heart infarction and in 50 patients with left inferior ventricular infraction only. In all survived patients additional selective coronarography was performed and in all died patients autopsy was performed. The aim of the study was to evaluate reliability of myocardial scintigraphy using 99m-Tc-pyrophosphate in the diagnosis of coexisting infarction of both heart ventricles. In a group of patients with coexisting right and left ventricular infarction (45 proved by coronarography, and 5 by autopsy), scintigraphic finding was confirmed in 46 (93%) patients. In all 50 patients with left inferior ventricular infarction, scintigraphic finding was confirmed in 48 of them by coronarography and in 2 by autopsy (100%). Of 4 patients with false negative scintigraphic finding 2 were treated with fibrinolytic therapy immediately after admission and in 2 diffuse occlusive changes were found on all three blood vessels by coronarography. It has been concluded that myocardial scintigraphy using 99m-Tc-pyrophosphate is a very sensitive (92%), specific (100%), exact (96%), simple and safe diagnostical method in detecting coexisting acute infarction of both heart ventricles.

Coronary Angiography↗

[Value of the stress test in the evaluation of the severity of ischemic heart disease].

Loading test was used in 156 patients with ischemic heart disease and the results of their selection are presented. In all patients occlusive coronary disease was detected by selective coronarography. They were divided in three groups. Two groups of patients had a high risk ischemic heart disease requiring surgical revascularization of the myocardium and selective coronarography. The first of these two groups comprised 48 patients with significant stenosis of the main tree of the coronary artery and the second comprised 35 patients with equivalent stenosis of this artery. The third group comprised 73 patients with ischemic heart disease of small risk in whom occlusive changes of the coronary arteries were of distal localization. The statistically significant difference was found between the two groups of patients with high risk and the third group with small risk according to early development of ST depression in the first minutes of loading, its degree, number of leads with ST depression, form and its maintenance after cessation of loading. The difference was also significant regarding the submaximal pulse rate and systolic blood pressure during loading test. It has been concluded that by using loading test as a functional diagnostic method patients with a high risk ischemic heart disease can be selected stressing the advantage of physiology over morphology.

Adult↗