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Biomedical subjects

S Cirković

Publications and source records attributed to S Cirković.

13 recordsLinked to original sources
PubMedDate not supplied

Brainstem auditory evoked potentials following head injury.

Brainstem auditory evoked potentials (BAEP) were examined in 40 patients with subjective disorders following closed head injury (CHI), with the established degree of recovery and performed CT-scan of the head. For all BAEP parameters the interval of normality was defined as 3 SD above and below mean value in the control group comprised of 20 healthy subjects. The upper limits of thus defined intervals of normality enabled the formation of four types of findings: type 1--normal finding that was registered in 23 (57.5%) patients; type 2 was a sum of individual findings with the prolonged interpeak latencies, but without the change of relative amplitude V:I--7 (17.5%) recordings; type 3--the findings where the fall of relative amplitude V:I was registered together with the prolongation of interpeak latency. It comprised of 4 (10%) recordings and the type 4 included 6 (15%) individual recordings with registered low RA V:I (0.8 or lower). The explanation of the most probable genesis of registered changes was presented.

Adolescent↗
PubMedDate not supplied

Cerebral infarction vs. intracranial hemorrhage--validity of clinical diagnosis.

In aim to improve the validity of clinical diagnosis of acute supratentorial ischemic cerebral infarction vs. intracranial hemorrhage, two different scoring systems were analyzed, each separately and combined, on one hundred eighty-eight patients sample. Results suggested higher sensitivity and positive predictive value for Guy's Hospital score, giving it higher importance in detection of hemorrhage, while combined application of both systems, in cases with identical findings, provided sensitivity 0.95 and 0.92 negative predictive value, in certain diagnosis category. A review of complete results disclosed that application of both systems separately didn't provide satisfactory diagnostic gain in differential diagnosis of that syndrome on our sample, while combined application provided high level of accuracy, eliminating simultaneously a significant proportion of patients (43.62%), as a category of uncertain diagnosis.

Aged↗
PubMedDate not supplied

[Carotid-cavernous fistula with spontaneous remission].

Carotid-cavernous fistulas (CCF) represent the complication of traumatic injuries mostly of bone structures of skull base and face, and rarely of soft neck tissues with the fast development of the shunt and imperiled hemodynamics that in a short time endangers the patient for the increase of intracranial mass. The therapy of this clinical entity significantly changed in the last few years. In this report, we present the case of spontaneous CCF healing with the complete restitution of neurological deficit and CCF healing in control angiographies.

Adult↗
PubMedDate not supplied

[Magnetic resonance findings and cerebrospinal fluid parameters in the evaluation of blood-brain barrier status and multiple sclerosis activity].

The diagnosis of disseminated demyelinating disease of central nervous system (DDD CNS) was established on clinical criteria, cerebrospinal fluid (CSF) analyses, electrophysiological and neuro-radiological examinations. The aim of this investigation was to perform an analysis of the state of blood-brain barrier and activity of demyelinating process in the patients, by the comparison of CSF findings and results of magnetic resonance (MR) examinations using paramagnetic contrast. Investigations were performed in 30 patients with DDD CNS in the phase of clinical impairment, without immunosuppressive/immunomodulatory therapy in the last 3 months. The results revealed the absence of correlation between CSF and MR findings, as in connection with the damage of blood-brain barrier, so in relation to immunologic activity of the disease. In the study are discussed the causes of these disparities that are the probable sequela of heterogenicity of physiopathologic events and disease forms inside DDD CNS.

Adult↗