Biomedical subjects
Publications and source records attributed to S Coca Menchero.
Tracheobronchial amyloidosis is the most common form of localized bronchopulmonary amyloidoses, although its diagnosis is not very frequent in daily practice. We present a case of localized tracheobronchial amyloidosis presented as hemoptysis. The diagnosis and treatment were performed with rigid bronchoscopy and resection with an Nd-YAG laser.
Primary malignant lymphoma of the bladder is a rare tumour. In a recent literature search only 70 cases have been found since 1885. Most of these tumours were low grade B-cell non Hodgkin's lymphomas and only 20% were high grade neoplasms. This tumour usually appears in women between 20 and 85 years (median 64 yr.) of age. 20% of them have antecedents of chronic cystitic. Some authors have considered that some of the primary malignant lymphomas of the bladder arise from the mucosa-associated lymphoid tissue (MALT), therefore acting like MALT lymphomas which affect the gastrointestinal tract, the salivary glands or the thyroid. We report three additional cases of primary malignant lymphoma of the bladder, two of high grade, and discuss the histological criteria that support their MALT nature.
The case concerned is one of lymphangiomyomatosis (LAM) in a woman aged 39, that after a episode of spontaneous pneumothorax was subject to medical research for progressive dyspnea of medium efforts and bloodstained sputum. High resolution CT showed numerous thin-walled cystic airspaces of varying sizes distributed diffusely throughout the lungs. The abdominal CT and ultrasound developed multiple right renal angiomyolipomas. The histopathological study of the sample obtained by open lung biopsy was conclusive of LAM. The main feature of this rare disease, which occurs almost exclusively in women of reproductive age, is the abnormal proliferation of immature smooth muscle at the level of the distal airway, small blood vessels and lung lymphatic system, including sometimes the mediastinal and retroperitoneal lymphatic system. The clinical, functional, radiological and differential diagnostic aspects with entities histopathologically similarities are discussed and the therapeutic possibilities are reviewed.
We report a case of inverted papilloma of the ureter, a rare disease entity. To our knowledge, this makes the 22nd case reported in the literature. Patient anatomopathologic work up included electron microscopy and immunohistochemical methods. This condition is compared to urothelial tumours of the ureter and we discuss the therapeutic approach. Correct treatment is by tumor excision including its base by segmental resection of the ureter and end-to-end ureterorrhaphy or ureterocystoneostomy in tumors of the lower third. A case submitted to endoscopic resection with good clinical results has been recently described by Cabezas Zamora. Perioperative biopsy does not appear to provide more data relative to the surgical option. Like other authors, we believe that these warrant the same close follow-up as in urothelioma.
Light and electronmicroscopic study of a Leydig cell testicular tumor in an 18-year-old male is presented. Bilateral gynaecomastia and normal hormonal blood levels were found. Emphasis on the diagnostic value of electronmicroscopy is remarked upon, based on the following ultrastructural characteristics of the cells; 1) Ovoid shaped nuclei with ondulating contours and dispersed and homogeneous chromatin, 2) Rich agranular endoplasmic reticulum with frequent special modifications, such as membranous whorls with a central cytoplasmic mass or lipid droplets, 3) Numerous mitochondria with occasional tubular cristae, 4) Numerous lipid vacuoles. Other structures also identified in this tumor are Reinke crystalloids, cytoplasmic microbodies, myelin figures, gap-type junctional complexes and paracrystalline inclusions of Payer type E, which are less common.
A case of syringoid eccrine carcinoma (SEC) is reported. The tumor was mainly formed by clear cells laden with glycogen. This feature, rarely found in syringoma, had not previously been reported in SEC. The authors assume that SEC is an infiltrating and locally destructive but not metastasizing neoplasm. They propose that SEC is a clinicopathologic entity with a histopathologic spectrum from the more differentiated syringomatoid ones to so-called primary cutaneous adenoid cystic carcinoma. A possible nexus between the more syringomatoid cases and the sclerosing sweat duct (syringomatous) carcinoma is also discussed.
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It has been done an analysis of a case of eccrine porome, based on the morphology, considering the actual tecnical publications on the matter. The morphogenesis of the formation of this nevoid tumor is established by the continuity between the main body of the tumor and the underneath eccrine sweat glands. These glands present signs of hyperplasia, which in the highest levels present destructuration of the excretory duct and morphological modifications of the cells which are conditioned by the functional adaptation at different levels. In this way there is proliferation of structures, similar to the different parts of syringuium and acrosyringuium producing this hamartomatous neoformation.
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Basaloid-squamous cell carcinoma is a rare tumor characterized by Wain et al in 1986 as a separate pathological entity. In head and neck more than 100 cases have been reported, with a strong predilection for hypopharynx, base of tongue, and supraglotic larynx. This entity also has been described in nasal cavity, oesophagus, tonsils and oral cavity. Only 14 cases has been reported arising in the floor of the mouth, and none in our literature. We present a new case in floor of the mouth and clinicopathological features are emphasized. We have undertaken moreover a bibliographic review of this uncommon and aggressive neoplasm.