PubMed HealthSearch

Biomedical subjects

S Collert

Publications and source records attributed to S Collert.

11 recordsLinked to original sources

Renal impairment after high doses of dicloxacillin-prophylaxis in joint replacement surgery.

The frequency of postoperative renal impairment after total hip and knee replacement was studied prospectively in 350 patients without signs of pre-existing renal disease. The first 278 patients were given dicloxacillin as prophylaxis against infection. In the remaining 72 patients dicloxacillin was excluded and gentamicin-impregnated cement was used as the only infection prophylaxis. In 35 patients in the first group (13 per cent), postoperative serum-creatinine was increased to pathological values. Thirteen of these patients were clinically affected, two had to be dialysed, and one died. In the second group there was no case of renal impairment. It is concluded that the systemic administration of antibiotics may be a cause of postoperative illness due to renal impairment.

Acute Kidney Injury

Osteomyelitis caused by Mycobacterium avium.

Osteomyelitis due to M. avium is extremely rare and frequently fatal. The successful cure of an 11-year-old patient with multiple mycobacterial lesions in the pelvis and right humerus is reported. Although the mycobacteria were in vitro resistant to most antituberculous drugs a five-drug regimen was given over a total of 2 1/2 years. The accumulated streptomycin dose was 160 g but no adverse effects were noted. Streptomycin therapy was judged of major importance for the favourable outcome.

Child

Chronic sclerosing osteomyelitis (Garré).

Eight patients with chronic sclerosing osteomyelitis (Garré) were investigated for an average follow-up of 13 years. The disease is a well definable clinical entity affecting children and young adults. Secondary lesions occurred in four cases after an average of 5.5 years. Five patients with a history of an average of eight years duration were free of symptoms. whereas the remaining three patients with a history of six, 13, and 15 years, respectively, had intermittent recurrences. The roentgenologic findings showed pronounced sclerosis interspersed with cystic areas. In all cases except one the sclerosis remained unchanged or progressed, even when the patient was free of symptoms. There are indications that the condition may have its origin in an infection caused by low-virulent, anaerobic bacteria. Present methods of treatment appeared to have little, if any effect, on the progress of the disease.

Adolescent

Osteotomy in osteoarthritis of the hip. A prospective study.

Ninety-two patients (94 hips), who in 1971--1972 underwent intertrochanteric osteotomy for painful osteoarthritis of the hip, were assessed and graded according to a well-defined rating system immediately before operation and 1 and 5 years postoperatively. At the 1-year follow-up pain was absent or only slight in 73.5 per cent of the patients. Five years postoperatively this figure had decreased to 45.5 per cent; 41.5 per cent of the patients deteriorated between the two investigations. Nineteen patients had been reoperated upon and total hip replacement performed. It was not possible to predict the effect of the osteotomy from the preoperative clinical and roentgenological picture. Nor was the operative procedure (amount of medial displacement, varus angulation, tenotomy of the iliopsoas) found to have any influence on the results. Though the effect of the osteotomy is not as long-lasting as previously believed, it is concluded that it still has a place in the operative treatment of painful osteoarthritis of the hip in younger patients.

Adult

Management of redislocated Colles' fractures.

One question which often confronts the clinician is whether or not a Colles' fracture, shown to be redisplaced, should be subjected to renewed reduction. Earlier reports have shown a rather good correlation between the accuracy of reduction and the functional and cosmetic end result. Roentgenograms of 40 rereduced Colles' fractures are reviewed in order to answer the following questions. What are the chances of a lasting improvement resulting from a renewed reduction of a redislocated Colles' fracture? What is the most suitable time for renewed reduction? Permanent improvement was found in about 1/3 of all the case. To establish the most suitable time for rereduction the material was divided into early rereduced (1-6 days after primary reduction) and late rereduced (7-15 days) fractures. It was found that early rereduction led to lasting improvement of the fractures position in only 2 of the 15 cases. Late rereduction led to permanent improvement in 15 of 30 cases with respect to dorsal angulation and in 9 cases to radial compression. If a rereduction is to be performed, it should be done during the second week after primary reduction.

Adult

Osteomylelitis of the spine.

A study of a series of 82 cases of pyogenic osteomyelitis of the spine has shown that the clinical features at the initial stage of the disease often present such a varied picture that the correct diagnosis may easily be overlooked for a long time. Once radiographic changes are demonstrated, the primary consideration in differential diagnosis is tuberculous spondylitis. Bacteriological verification by needle biopsy or surgical exploration is recommended in order to institute an adequate antibiotic therapy. Surgical evacuation is advocated in cases with extensive vertebral destruction. The majority of patients recovered within 1 year from the onset of illness. In slightly more than half of the cases the spinal lesions healed with spontaneous interbody fusion. This tendency was most pronounced in cases of cervical and upper thoracic involvement. No deaths occurred as a result of the spinal disease.

Adolescent

Surgical management of fracture of the captulum humeri.

A follow-up study of 20 patients operated upon for fracture of the capitulum humeri is reported. In 8 cases the fracture fragment was removed while in 12 others open reduction was performed. Open reduction gave the best results and is therefore recommended as the treatment of choice.

Adult