Biomedical subjects

S Cottle

Publications and source records attributed to S Cottle.

3 recordsLinked to original sources

PubMed1993

Inhibitory effects of tea extracts and (-)-epigallocatechin gallate on DNA synthesis and proliferation of hepatoma and erythroleukemia cells.

Polyphenols extracted from green or black tea with ethyl acetate were strongly inhibitory for DNA synthesis in HTC rat hepatoma cells and DS19 mouse erythroleukemia cells at concentrations of 0.1-0.2 mg/ml. There was less inhibition with a subsequent black tea fraction extracted with butanol and with the residual water-soluble fraction. Although cell proliferation was inhibited by (-)-epigallocatechin gallate and the tea extracts, there were only marginal effects on differentiation of DS19 cells as judged by hemoglobin synthesis.

Animals↗

PubMedDate not supplied

Temporary transvenous cardiac pacing.

This article is the seventh in our Care is Critical series which continues to look at the more complex interventions nurses now have to manage in acute general wards and the community. This article considers the use of cardiac pacing and takes us through the normal conduction system, types of pacemakers, and insertion and management of the line and generator. It also outlines common problems and dangers associated with this intervention.

Cardiac Pacing, Artificial↗

PubMedDate not supplied

Nurses' under-medication of analgesia in cardiac surgical patients: a personal exploration.

This paper examines aspects of care which may account for some of the reasons why critical care nurses fail to relieve patients' pain following cardiothoracic surgery. Factors that may influence the critical care nurses' decision regarding the amount of opiate analgesia to give a patient are examined using the 'Theory of Planned Behaviour' as a framework for enquiry. The skills required by the critical care nurse in planning how to play the phenomena of 'the doctor-nurse game' may be a key element in meeting the goal of pain relief for the patient following cardiac surgery.

Analgesics, Opioid↗