PubMed Health⌕ Search

Biomedical subjects

S Cuomo

Publications and source records attributed to S Cuomo.

48 records · Page 3Linked to original sources
PubMed1982

[Influence of myocardial infarct on ventricular arrhythmias during the exercise test. Study in patients with stable angina of effort].

The incidence of ventricular arrhythmias observed during exercise (EVA) was correlated with the presence of previous myocardial infarction (IM) and angiographic severity of coronary artery disease (CAD) in 162 patients (pts.) with stable angina on effort, who had a positive stress test and greater than 70% stenosis of a major coronary artery. Our study population was divided in two groups: the first was composed of 95 pts. with previous MI, the second of 67 pts. without previous MI. Pts. of both groups were subdivided according to severity of CAD and to presence and degree of abnormal segmental wall motion (ASWM). In the MI group only 11.5% of pts. had single vessel disease, and 86.3% had ASWM. In pts. without MI 28.6% had single vessel disease; ASWM was found in 59.7% (p less than 0.001 vs MI pts.). Pts. with MI showed a higher incidence of EVA than pts. without MI (60% vs 32.8%, p less than 0.001). In both groups EVA were more frequent among pts. with double, triple vessel and main left CAD, than in pts with single vessel disease, but the difference was not significant. In general, EVA were found to correlate better with the number of areas with ASWM: in both groups significant differences of EVA frequency were found when pts. with normal left ventricular function were compared to those with more severe ASWM, while no difference was found between pts with and without MI who had the same degree of CAD. The most severe EVA (Tilkian's classification), were found in pts with a previous MI and a high ASWM score. In conclusion, our results show that a previous MI affects the development of EVA in pts. with stable effort angina. However EVA seem to be better correlated with the severity of LV impairment than with the extent of CAD.

Adult↗
PubMed1981

[The vectorcardiogram pattern of the athlete's heart (author's transl)].

In order to assess the vectorcardiographic pattern of the athlete's heart, we evaluated the vectorcardiograms of 17 professional footballers; the signs of ventricular hypertrophy were particularly studied. 9 athletes had left ventricular hypertrophy, 3 showed VCgraphic signs of combined ventricular hypertrophy and 5 had normal vectorcardiograms. In all athletes with left ventricular hypertrophy the initial forces had normal spatial orientation (I A left ventricular hypertrophy). Likely, the combined right ventricular hypertrophy explains these VCgraphic patterns. The QRS loop did not show abnormal morphology, only the high magnitude of the spatial maximum QRS vectors was significant for diagnosis of left ventricular hypertrophy. The increase of the cardiac volumes induced by training might explain the high magnitude of the QRS loop.

Adult↗
PubMed1981

[Serial evaluation by effort test of the effects of coronary artery bypass on effort angina (author's transl)].

To evaluate the duration of favourable effects of coronary artery bypass (CAB) on exercise-induced angina (A), 58 patients: 13 with single 21 with double and 24 with triple vessel disease, were studied. All patients underwent CAB for stable angina on effort. Patients underwent exercise testing (ET) before surgery at one, two and three years. Heart rate peak (HR), HR x systolic blood pressure peak (DP), work load (W), exercise-induced ST segment depression (ST) and incidence of A were evaluated; the results of ET before surgery were compared with those found after CAB. Our findings show that HR, DP, W and ST were significantly improved by surgery for at least 3 years. The lowest incidence of A was found at one year ET (20.6%), while it increased at two years (27,5%) and three years ET (37.9%). Most patients with A had angiographic evidence of left ventricular abnormal wall motion and ec-graphic signs of previous myocardial infarction. Our data indicate that serial exercise testing can objectively monitor the results of CAB. Most patients show an improved exercise tolerance for up to 3 years after CAB. Some patients, with more extensive CAD, showed a progressive deterioration of the clinical pattern and a decrease of the exercise tolerance.

Angina Pectoris↗
PubMed1981

[Influence of left ventricular volume changes induced by Valsalva maneuver on R wave amplitude (author's transl)].

Exercise-induced changes of R wave amplitude (delta R) during exercise has been employed to improve the reliability of stress testing in detecting patients with coronary artery disease. Several authors postulated that delta R are related to changes of ventricular volumes. Furthermore Valsalva Maneuver (VM) is able to induce a decrease of left ventricular volumes induced by VM and the variations of R wave. Echocardiographic method was used to determine left ventricular volumes and R wave amplitude changes were evaluated by Frank's lead. Our findings suggest that R wave amplitude changes are not related to variations of cardiac volume. Electrophysiological mechanisms of delta R need further investigation.

Adolescent↗
PubMed1981

[Effect of age on heart rate and systolic time intervals in children, adolescents and young adults (author's transl)].

Study was performed to assess if the increase of age can affect heart rate (HR) and systolic time intervals (STI) in a population of children, adolescents and young adults. We made polygraphic recordings in 66 normal subjects (5-25 years old) and regression equations were obtained for STI and age, HR and age and STI and HR. We found a significant relationship of HR and STI with age. Equally STI were correlated with HR. PEP/LVET ratio was unaffected by age or HR. We considered moreover mean values of HR and STI in four age-groups (5-10, 11-15, 16-20, 21-25). Data comparison showed higher LVET and lower HR in elder subjects. These had moreover higher PEP versus younger groups. The Authors believe that the relationship of HR, STI and age, undemonstrated by several other studies, can be found if we consider a large of age. Because other authors studied a little range of age, our demonstration of no statistically significant different values of HR and STI between 5-10 and 11-15 groups, authorize us to consider that the effect of age is highly significative on HR and STI among children, adolescents and young adults.

Adolescent↗
PubMed1980

[Correlations between angiocardiography and changes of R wave amplitude during effort in patients with coronary heart disease (author's transl)].

The Authors studied correlations between angiocardiography and changes of R wave amplitude (delta R) during effort in 113 patients. They showed coronarographic evidence: 69 with stenosis greater than or equal to 70% of at least one major coronary vessel and 44 with no significant lesions. delta R values greater or equal than 0 were considered as pathologic. delta R appeared greater than or equal to 0 in 8 of 14 patients (57%) with single stenosis, 4 (28%) with abnormal wall motion (AWM). delta R increase or unchanged in 26 of 31 (84%) patients with double stenoses, 25 of them (81%) with AWM. delta R was greater than or equal to 0 in 22 of 24 (92%) with triple stenoses. In subjects with milk coronary artery disease (CAD) R wave increased or unchanged in 47% (19/44). Pathologic changes of R wave are highly frequent in CAD patients, especially in those with severe impairment. These changes, however, are not specific or costant because they appeared enough frequently in subjects with normal doronary vessels, and, moreover, R wave may decrease also in CAD patients with severe impairment. The Authors consider that evidence of delta R values greater than or equal to 0 may not be considered as a sign of CAD, but it must be evaluated with the other data showed by ergometric tests.

Adult↗
PubMed1980

[Diagnostic availability of R wave changes during effort test for a diagnosis of coronary artery disease (author's transl)].

New ecgraphic criteria has been proposed to improve diagnostic availability of R wave changes (delta R) and algebra summation of delta R and ST segment depression (delta RST) in comparison to the criterion of ST depression (ST). The AA. considered as a positive test for a diagnosis of coronary artery disease (CAD): delta R and delta RST values greater than or equal to 0. In 69 patients with stenosis, 75% of at least one major coronary vessel, delta RST showed correct diagnosis in 87% of cases, R in 81% and ST in 73%. RST sensitivity was better than that of ST (P = 0,02). In 44 patients with normal coronaries delta RST was able to correct diagnosis in 52% of cases, delta R in 57% and ST in 73%. ST specificity was better than that of delta RST (P = 0,04). Predictive accuracy was comparable for the three criteria. In normal healthy subjects everyone with an exercise test negative for CAD, with ST analysis, delta R and delta RST was 0 in 16% of cases. New ecgraphic criteria, also showing a better sensitivity in comparison with ST segment analysis, have a worsened specificity. The Authors do not consider these methods a significant improvement in ecgrahic evaluation of exercise test.

Adult↗