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Biomedical subjects

S Curwin

Publications and source records attributed to S Curwin.

4 recordsLinked to original sources

Adaptation of rat knee meniscus to prolonged exercise.

The morphological and biochemical adaptations of knee meniscus to prolonged exercise were studied. Female Sprague-Dawley rats maintained under controlled environmental conditions were randomly assigned to either an endurance-trained or a sedentary group. Training consisted of a progressive exercise protocol on a motor-driven treadmill, 5 days/wk for 12 wk. Knee lateral menisci were obtained from anesthetized rats and used for morphological and biochemical analyses. Gastrocnemius succinate dehydrogenase increased 65% in the endurance-trained group, as evidence for a training effect. In the trained group, collagen, proteoglycan, and calcium concentrations increased significantly in the posterior region of the lateral meniscus. In contrast, no significant changes were found in the anterior region of the lateral meniscus. The region-specific changes in meniscal concentrations of calcium and matrix macromolecules in response to prolonged exercise are consistent with the distinctly different mechanical properties and functional roles of the anterior and posterior regions of the rat knee meniscus.

Adaptation, Physiological↗

Eccentric exercise in chronic tendinitis.

Chronic tendinitis, particularly of the Achilles tendon, frequently outwits traditional programs of therapy including surgery and/or prolonged immobilization. A hypothesis proposes that disruption of the tendon, micro or macro, occurs under specific conditions of eccentric loading. In order for the healing tendon to be adequately rehabilitated, the treatment program must include specific eccentric strength rebuilding exercises.

Chronic Disease↗

Tendinitis: the analysis and treatment for running.

The material presented has been designed to offer an approach to the diagnosis and treatment of chronic tendinitis in the runner. Although there is a paucity of experimental data dealing with the behavior of the muscle-tendon unit during lengthening contractions as compared with the volume that exists concerning shortening contractions, results indicate that force increases with length from both eccentric and concentric contractions. The literature also suggests that eccentric contraction is a means by which muscles can maximize their force production while minimizing time delays and energy expenditure. Using this information in our clinical experience, we have developed an exercise program to treat chronic tendinitis. Pain, the cardinal sign of tendinitis, is used as both a way to classify the severity of the tendinitis and a yardstick for the progress of treatment.

Adrenal Cortex Hormones↗

Medial epicondylitis. An electromyographic analysis and an investigation of intervention strategies.

Flexor and extensor muscle-tendon unit activity at the elbow during the golf swing was recorded from subjects with and without medial epicondylitis. There was no significant difference in total swing time between symptomatic (1.23 +/- 0.15 sec) and asymptomatic (1.15 +/- 0.13 sec) subjects nor between golfers with low (1 to 6 handicap, N = 8) and high (11 to 19 handicap, N = 8) scoring abilities. Symptomatic and asymptomatic subjects displayed similar electromyographic profiles for flexor and extensor muscles of the forearm. Electromyographic activity of the common extensor muscles was persistent throughout the four swing phases, ranging from 33.59% of maximum voluntary contraction at address to 58.77% at contact. Common flexor muscles produced a consistent burst of electromyographic activity during contact phase (flexor burst, 90.77% of maximum voluntary contraction). Symptomatic subjects' mean flexor muscle electromyographic activity was significantly greater than that of asymptomatic subjects in both address and swing phases. When forearm brace and oversized grips were imposed on symptomatic subjects, there was no significant difference in mean electromyographic magnitude or muscle activation pattern during the golf swing. Thus, the method of symptomatic relief of the intervention strategies tested is still in question.

Adult↗