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Biomedical subjects

S D Fomin

Publications and source records attributed to S D Fomin.

12 recordsLinked to original sources
PubMed1994

Neutron brachytherapy in the treatment of melanoma.

PURPOSE: The use of Cf-252 for treatment of cutaneous malignant melanoma is presented. METHODS AND MATERIALS: From 1975 to 1992, plaque Cf-252 applicator neutron brachytherapy was performed in nine patients with skin malignant melanoma of head and neck or chest wall. Neutron brachytherapy alone was applied in six patients; two patients received neutron brachytherapy before and one after photon teletherapy. Tumor neutron brachytherapy doses ranged from 3.9-11.5 Gy. Four patients underwent surgical resection of the primary tumor and in six cases, regional lymph node dissection was done. RESULTS: The patients survival times ranged from 3 months to 12 years; 2-year survival was 50% and 30% of the patients lived 3 years. The mean survival time was 39 months. All but 1 patients died because of distant metastases. Local tumor control was achieved in all cases. CONCLUSION: The clinical study shows the relative sensitivity of melanoma to the neutron irradiation and offer new possibilities in Cf-252 brachytherapy.

Adult↗
PubMed1994

Management of a patient with synchronous squamous cell cancers of the oesophagus and stomach.

Synchronous tumours of the oesophagus and stomach are relatively rare and principles of diagnostics and treatment are still the matter of discussion. Either primary tumours or primary and metastatic lesions in the oesophagus and stomach have been described. The difficulty of diagnosing the gastric lesion and necessity of fast decision making during surgery are reasons to discuss this case.

Carcinoma, Squamous Cell↗
PubMed1992

[Primary retroperitoneal adenocarcinoma].

A rare case is reported of retroperitoneal papillary adenocarcinoma in a 25-year-old female. Two recurrences were observed after surgical and radiation treatment. The tumour became inoperable after the second recurrence. The duration of the disease was somewhat more than 5 years. The attention is drawn to the difficulty of differential diagnosis with a metastasis. The young age and histological structure allow one to regard the tumour disembryogenetic and originating from the embryonal germs of urinary-genital organs or from the intestinal tube.

Adenocarcinoma, Papillary↗
PubMed1991

[Radiation-induced human osteogenic sarcoma].

The authors studied clinically, roentgenologically and morphologically 8 patients with radiation osteogenic bone sarcomas which the patients developed 9 to 24 years (15 years, on the average) after distant gamma therapy at total local doses from 35 to 111 Gy (average 63 Gy) for primary skeletogenic and non-skeletogenic tumors when the bone was in the zone of irradiation. Radiation osteogenic sarcomas developed when the women or patients at early age were irradiated. Osteosclerotic (3), osteoblastic (2), osteoid (1), chondroblastic (2) forms of osteogenic sarcoma were identified. Necrotic and regeneratory bone changes preceding tumour growth may be found that alter the roentgenomorphological correlations.

Adolescent↗
PubMed1988

[A rare case of rupture of a syphilitic aortic aneurysm into the esophagus].

A case of the rupture of a syphilitic aortic aneurysm into the esophagus in a woman aged 64 with cured breast cancer was observed. A clinical picture, autopsy and microscopy findings were described. The authors underlined the rarity of the case, difficulty of intravital and morphological diagnosis which could be attributed to syphilis pathomorphosis. Of great importance for diagnosis are a detailed life history, clinical symptoms, instrumental methods of investigation, especially in oncological practice where differential diagnosis with exophytic esophageal cancer seems difficult.

Aorta, Thoracic↗
PubMedDate not supplied

[Ultrasonic endoscopic examination of the upper portion of the gastrointestinal tract].

Thirty-two patients with various diseases of the esophagus, stomach, and the adjacent organs (pancreas, liver and spleen) were examined to assess the potentialities of transesophageal ultrasonic endoscopy. The results were compared with the findings of fiber gastroscopy, x-ray and ultrasonic transabdominal examinations. Nineteen patients were examined for a malignant involvement of the esophageal and gastric wall and tumor progress at the site of anastomosis after combined treatment of gastric cancer. Ultrasonic endoscopy data were confirmed during subsequent surgical interventions and histologic examinations of the resected tumors.

Adenocarcinoma↗