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Biomedical subjects

S D Strano

Publications and source records attributed to S D Strano.

6 recordsLinked to original sources
PubMed1995

[Surgical treatment of nonpalpable mammographic abnormalities using guidewire localization].

Mammography remains the recommended method of detecting nonpalpable breast lesions. With increasing use of mammography as a screening and diagnostic modality for breast disease, more needle-localized biopsies are being performed. Preoperative localization of lesions detected by mammography enables the surgeon to resect affected breast tissue more accurately. The surgical biopsy should be a 1-step procedure with wide local excision. If it reveals malignancy, further surgical treatment should be planned, based on the clinical and pathological data. In our prospective study biopsies with localization were performed in 68 women; in 21 (30.9%) malignancy was found: solitary duct cell carcinoma in situ in 10 (multifocal in 4), duct cell carcinoma in situ with microinvasion in 3, and invasive carcinoma in 8. Lobular cancer was not found. Treatment consisted of mastectomy in 10 and breast conservation surgery in 11. Further studies are needed to clarify issues involved in surgical management of carcinoma-in-situ.

Biopsy, Needle↗
PubMed1995

Quantitative comparison of two distinct echogenic structures appearing on the same image using gain-assisted densitometric evaluation of sonograms (GADES).

Gain-assisted densitometric evaluation of sonograms with two distinct echogenic structures appearing on each image was performed to establish if their density-gain setting curves have similar inclinations. We used the breast model (n = 67) in which hyperechoic masses were compared to the surrounding hyperechoic tissue at the optimal gain (Gopt) and at Gopt + 5. Both structures had significantly different film-corrected densities and showed a linear decline of density as the system gain increased from Gopt - 5 to Gopt + 5. The least squares regression lines were almost parallel. The density-gain unit decrease from Gopt - 5 to Gopt was not different, but the decrease from Gopt to Gopt + 5 reached statistical significance. The data suggest that skewed values are theoretically possible in comparing two distinct echogenic structures. However, within the gain intervals used in GADES, these differences are negligible and comparisons are as accurate as with the assessment of a single echogenic structure.

Breast Neoplasms↗
PubMed1995

Echogenicity of fibroadenoma and carcinoma of the breast. Quantitative comparison using gain-assisted densitometric evaluation of sonograms.

The purpose of this study was to evaluate the role of ultrasonography in differentiation between the echogenic characteristics of carcinoma and those of fibroadenoma of the breast. Two mathematical transformations of the measured density on a sonographic image of the breast lesion at three different system gain settings were used in cases of carcinoma (n = 16) and fibroadenoma (n = 31) to provide standardized density values. A significant correlation was found between the tumor and the surrounding tissue densities in both carcinomas (r = 0.77, P = 0.0004) and fibroadenomas (r = 0.79, P < 0.000001. The mean standardized density of the tumor was significantly higher (P < 0.0001) than the surrounding tissue in both carcinomas (2.03 +/- 0.64 D versus 1.23 +/- 0.38 D) and fibroadenomas (2.09 +/- 0.48 D versus 1.33 +/- 0.3 D). However, the differences between density values of carcinoma and fibroadenomas were not significantly different. The data suggest that it may not be possible to differentiate breast carcinoma and fibroadenomas on the basis of the echogenicity of solid breast masses.

Adolescent↗