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S Dadparvar

Publications and source records attributed to S Dadparvar.

24 records · Page 2Linked to original sources

Demonstration of a malignant soft-tissue lymphoma during triple-phase skeletal scintigraphy.

Malignant soft-tissue neoplasms may be demonstrated in the course of triple-phase skeletal scintigraphy due to the presence of either abnormal vascularity or calcifications. We report the unusual case of a malignant lymphoma which was detected in the vascular phases of a triple-phase skeletal scintigraphic study but was not visualized utilizing conventional radioangiographic techniques. Lymphoma should be included in the differential diagnosis of soft-tissue neoplasms demonstrable by scintiangiography.

Edema↗

Subcapsular splenic hematoma vs intrasplenic pancreatic pseudocyst.

An intrasplenic pancreatic pseudocyst may mimic a subcapsular splenic hematoma. Misdiagnosis of this entity may have serious consequences. Particular care should be taken when a patient presents with a cystic mass in the region of the spleen and a history of chronic alcohol abuse, regardless of the presence or absence of a history of a traumatic episode. Thin-needle aspiration is the current diagnostic modality of choice. A high fluid amylase level establishes the diagnosis of an intrasplenic pancreatic pseudocyst.

Adult↗

Implications of lymphoscintigraphy in oncologic practice: principles and differences vis-a-vis other imaging modalities.

The prompt availability of interstitial lymphoscintigraphy and its utilization offer significant advantages over other techniques. Computed tomography represents a highly sensitive technique that suffers from lack of specificity in detecting small lesions. The expense and accessibility of machine time limit its usefulness as a routine survey procedure. Radiographic lymphangiography represents a tedious and difficult process necessitating identification of lymphatic channels for injection of the contrast material for visualization of the lymph nodes in the region being evaluated. With these demonstrated difficulties, the lymph node scanning technique has emerged as a simple, reliable, and reproducible technique for evaluation of multiple lymph node groups.

Antimony↗

The role of Tc-99m HMPAO functional brain imaging in detection of cerebral radionecrosis.

BACKGROUND: Cerebral radionecrosis is a possible complication of brain radiation therapy in patients with primary or metastatic tumors. This retrospective study evaluated the role of Tc-99m hexamethyl propyleneamine oxime (HMPAO) scintigraphy in monitoring the effects of radiation on the brain. METHODS: Ninety-eight patients (41 female, 57 male) with a mean age of 51 years (range, 16-82 years) underwent 128 sets of single-photon emission computed tomography studies. TI-201 and Tc-99m HMPAO single-photon emission computed tomography studies were performed for tumor localization and evaluation of the effect of radiation on the cerebral cortex. Thirty concomitant neuropsychological tests and 96 anatomic imaging (computed tomography/magnetic resonance imaging) were performed. The average radiation dose was 52 Gy delivered as 1.8 to 2 Gy/fraction. Thirty-two patients received an average dose of 160 mCi of I-125 EGFr concomitantly. The average follow-up period was 34 months. Abnormalities away from the tumor site were interpreted as positive on HMPAO studies, neuropsychological testing, or anatomic imaging; otherwise, they were classified as negative. RESULTS: There were 10/45 (22%) and 75/83 (90%) abnormal HMPAO study results before and after radiation therapy. The HMPAO studies compared with neuropsychological testing showed 3/13 (23%) and 14/17 (82%) concordant abnormalities in addition to tumor site in patients pre- versus postradiation therapy. There was better concordance of HMPAO and anatomic imaging in 22/30 (76%) patients versus 24/67 (36%) patients before radiation therapy. HMPAO imaging after radiation therapy revealed significantly more perfusion abnormalities. There were significant differences between all of the aforementioned parameters. CONCLUSION Tc-99m HMPAO imaging is useful in the evaluation of the effects of radiation therapy on the brain and is highly concordant with neuropsychological testing. It is superior to anatomic studies in identifying radiation-induced changes.

Adolescent↗