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Biomedical subjects

S Dally

Publications and source records attributed to S Dally.

18 recordsLinked to original sources

Subclinical impairment of colour vision among workers exposed to styrene.

The effects of exposure to styrene were studied among 60 men aged 20 to 56 (mean 29.5) employed in shipbuilding. Exposure was due to the handling of glass reinforced polyester materials. The study was cross sectional and the workers were compared with a control group matched for age, social and occupational state, and ethnic origin. During the study, the mean atmospheric exposure to styrene was 24.3 ppm. Mean urinary elimination was 230 mg/g creatinine for mandelic acid and 57.4 mg/g creatinine for phenylglyoxylic acid. The Farnsworth 100 hue test showed no significant differences between the exposed and control groups for error scores. A significant difference was found, however, for the number of subjects with errors axis in the red-green, or blue-yellow ranges, or both, which was larger among the exposed workers (32/60 v 20/60 for the controls (p < 0.05)). Psychometric tests were also conducted, using the World Health Organisation (WHO) neurobehavioural core test battery. Of the seven tests it included, anomalies were only found for the aiming test. These results suggest that exposure to moderate styrene concentrations of the order of 25 ppm can lead to impairment of colour vision.

Adult

Emmetropisation, squint, and reduced visual acuity after treatment.

In a sample of children used to assess the value of optical correction of hypermetropia from the age of 6 months the refraction of the most hypermetropic meridian frequently became less than 3.5 D as the children grew. When this occurred, the incidence of squint was significantly less (p less than 0.001) and the last known acuity after treatment was significantly better (p less than 0.001) than when it did not. This process of emmetropisation appears to have been impeded by the consistent wearing of hypermetropic spectacle correction from the age of 6 months.

Eyeglasses

[Acute tubular necrosis in acute alcoholic hepatitis with cardiac beriberi (author's transl)].

In one case of fulminant hepatic failure by acute alcoholic hepatitis, renal failure seemed to be related to active renal vasoconstriction by systemic endotoxemia due to impaired hepatic clearance of toxins, associated with or complicated by a located intravascular coagulation with acute tubular necrosis. The associated thiamin deficiency may have accentuated this renal vasoconstriction.

Acute Disease

[Periarteritis nodosa in an addict with a hepatitis B injection (author's transl)].

The authors describe a case of a drug addict with a hepatitis B who was found to have periarteritis nodosa and a nephrotic syndrome. The course was rapidly fatal and autopsy confirmed the diagnosis. This new case questions the hypothesis suggested of possible toxicity of hard drugs (especially the amphetamines) as being an etiological factor for periarteritis nodosa observed in addicts. Hepatitis B virus, which is involved in the etiology of periarteritis nodosa and some nephrotic syndromes (also reported in addicts) is, in fact, very prevalent in users of hard drugs by the parenteral route.

Adult

Blood cadmium level and hypertension in humans.

Blood cadmium level was determined in 29 nontreated hypertensive male subjects and 29 controls. All were individually matched for sex, age, and smoking habits. No differences were found between hypertensives (3.3 +/- 0.4 ng/ml) and normotensives (2.6 +/- 0.4 ng/ml).

Adult

[Multi-focal tuberculosis].

The authors present 16 cases of multifocal tuberculosis observed over a period of five years on a general medical unit. These cases almost all occurred in immigrants. (14 out of 16) with at least 2 localisations in 9 of them and sometimes 3 or more. The viscera usually affected were, in order, the liver, the lymph nodes, the lungs and pleura, the joints. They emphasise the mildness of the clinical symptoms, the rareness of lung involvement and, on the contrary, the constancy of hepatic involvement so that needle biopsy of the liver is essential in diagnosis.

Adult

[Hypoglycemia in 2 patients treated with perhexiline maleate].

Hypoglycaemia occurred in two patients treated with perhexiline maleate. The responsibility of the medication is discussed in each case. Blood insulin levels were increased. Blood perhexiline levels decreased very rapidly in the first patient, though much more slowly in the second.

Aged

[Toxicity of dioxin].

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2,4,5-Trichlorophenoxyacetic Acid

[Infectious endocarditis in a neurosurgical unit].

Clinico-pathological study of 15 cases of cerebral complications of bacterial endocarditis referred to a neurosurgical unit for suspected cerebral abcess. In all cases but one, cerebral symptoms appeared with the cardiac condition undiagnosed, and complete diagnosis was made only at autopsy. Cerebral lesions consisted mainly in focal softening due to embolisms, generally multiple, with in about half the cases histological manifestations of bacterial seeding, without any abcess such as could be amenable to neurosurgical treatment. Surgical treatment of mycotic aneurysms was unsuccessful, due mainly to their multiplicity.

Adolescent

[Neurocomportmental disorders in an urban population exposed to lead].

A study was performed in 278 people living in a Mexican town with a high lead environmental pollution. Lead blood level was found very high (m:59.7 micrograms/l) and some abnormalities were also found for free erythrocyte Protoporphyrin and ALA dehydratase. A significant dose-response relationship was also found with somatic complaints like loss of appetite, insomnia and headache.

Environmental Exposure