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Biomedical subjects

S Deredzhian

Publications and source records attributed to S Deredzhian.

9 recordsLinked to original sources
PubMed1991

[The extracorporeal lithotripsy of gallstones in Bulgaria].

Extracorporal lithotripsy is a new, modern method of treatment of gallstone disease. The effect of the treatment was evaluated as follows: full--fragments up to 2 mm in size (in 60.5% of the patients), partial--fragments between 2 and 5 mm in size (in 30.1% of the patients) and no effect--fragments larger than 5 mm or lack of fragmentation (in 9.4% of the patients). Complications during the manipulation and after it were very rare--allergic in 1.7% and obstructive in 6.7% of the patients. In only 3 patients on operation had to be done. 84 patients were followed up for 270 or more days. In 10.4% of the patients a full clearance of the fragments was found, and in 28.2% of the patients there was only a reduction of their number. Extracorporal lithotripsy followed by litholytic therapy is a perspective method for gallstone disease treatment. It has wide indications, few contraindications, is well tolerated and is with a low complication rate.

Bulgaria↗
PubMed1989

[Barrett's esophagus].

In 12 patients the endoscopic examination raised the suspicion of Barrett's syndrome. By means of guided biopsies and static scintigraphy with gamma camera and 99m-technetium pertechnetate ectopic gastric mucosa was found in the esophagus of 5 of the patients. In one patient a Barrett's ulcer was found. The establishment of a focus of increased radioactivity proximal from the stomach by static scintigraphy is a proof for the presence of ectopic gastric mucosa in the esophagus. Because of the high risk of malignancy a systemic endoscopic biopsy control is necessary for the patients with proved columnar-cell metaplasia in the esophagus.

Adult↗
PubMed1984

[Case of a biliodigestive fistula--a variant of Bouveret's syndrome].

The female patient N. I. G., aged 65, case report No 21336/416 was admitted to the Clinic of Gastroeneterology on October 12, 1982, with the following diagnosis: Cholelithiasis, Cholecystitis chronica calculosa, Fistula biliodigestiva. The anamnestic data, the objective examination as the data from operation protocol revealed that the case reported was a peculiar, very rare, favourable evolution of Bouveret syndrome. The biliary concrements (the biggest 10 X 15 mm), that had passed through the fistula opening into the permanently deformed and constricted duodenal bulb have twice caused short-term disturbed intestinal passage. The patient, with the vomited juices, had thrown out the concrements that caused the obturation, resulting into restoration of the intestinal passage and clinical improvement. The surgical operation was performed 57 days after the acute incident for removing of gallbladder and elimination of the fistula passage.

Aged↗
PubMed1983

[Serum gastrin levels before and after short-term treatment of duodenal ulcer with cimetidine and pirenzepin].

Serum gastrin was studied before meals in 71 patients with duodenal ulcer, treated with various doses of simetidin and pyrensepin. Gastrin level was elevated after a treatment with 1 g simetidin daily and 125 mg pyrensepin, and remained unchanged with pyrensepin treatment (50 and 100 mg daily). A tendency to decreased gastrin level was observed after the treatment with simetidin 400 mg daily. Under those circumstances the attempt at duodenal ulcer treatment with lower simetidin doses, than the usual, is justified.

Adult↗
PubMed1981

[Gastric acidity in a double ulcer (of the stomach and duodenum)].

Gastric salt-acid secretion was studied in three comparative patient groups with gastric ulcer, endoscopically confirmed, combination of gastric and duodenal ulcers. In the patients with double localization of the ulcer (stomach and duodenum) - hyperacidity was determined after pentagastrin stimulation. Acid-salt secretion was higher than that of the patients with gastric ulcer and was close to the secretion of those with duodenal ulcer, being but with a high standard deviation, necessitates consideration to be given to each concrete case of treatment. No discrepancy in the volume of gastric secretion before meals was established, thus impugning the role of pylor stasis in the genesis of secondary gastric ulceration. The incidence of atrophic gastritis in case of gastric and double ulcer is almost identical, hence attention is paid to the duodeno-gastric reflux as an eventual cause for damaging gastric mucosa with its successive ulceration in the patients with duodenal ulcer of many years. That is the reason, drugs enhancing the resistance of gastric mucosa as well as methoclopramid intake are proposed additionally to the drugs, neutralizing or blocking the gastric acid-salt secretion.

Adult↗