Purification of urinary luteinizing hormone (LH) from human menopausal gonadotrophin.
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Chromatography↗
Biomedical subjects
S Donini
Publications and source records attributed to S Donini.
Family factors associated with the use of psychotropic drugs, alcohol abuse, and minor psychiatric morbidity in the community.
The association of family health and family structure factors with psychotropic drug consumption, alcohol abuse, and minor psychiatric morbidity was investigated in a representative community sample of 151 respondents by means of a logistic multiple regression analysis. A General Health Questionnaire GHQ score of 5 or above was best predicted by undesirable events, sex, the number of generations, marital status, and the number of family members with a high GHQ score. Psychotropic drug consumption was best predicted by the number of family members with distress manifestations, while alcohol abuse in men was predicted best by events of the exit type.
Adaptation, Psychological↗
Effect of natural beta-interferon on estrogen receptor mRNA of breast cancer cells.
We have demonstrated that natural beta-interferon (beta-IFN) enhances estrogen receptor (ER) mRNA of a human breast cancer cell line, CG-5. Cells were sensitive to the effect of beta-IFN at concentrations ranging from 10 to 100 IU/ml. The increase of ER mRNA was seen after 48 hr of treatment in at least three separate experiments. Our results are in agreement with the previously observed enhancement of receptor protein. In addition, they suggest that the IFN-induced promotion of the antiproliferative activity of drugs which act via ER may be due, in part, to increased receptor synthesis.
Blotting, Northern↗