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S Dubecz

Publications and source records attributed to S Dubecz.

32 records · Page 2Linked to original sources
PubMed1986

[Early operation of acute appendicitis--risk in unnecessary appendectomies].

The authors have analysed their own surgical patients, with the view to establishing the rate of unnecessary appendectomy. Any operation is accompanied by a certain risk, including appendectomy. Hence, unnecessary interventions should be avoided. Complications usually concomitant with appendicitis may occur, as well, in the wake of unnecessary appendectomy. Yet, they are much more common, when an operation had been delayed.

Acute Disease↗
PubMed1986

[Use of sham feeding tests in the control of complete denervation of the stomach in selective proximal vagotomy].

Sham-feeding tests were preoperatively and postoperatively used by the authors in an attempt to check on completeness of selective proximal vagotomy. The quotient of sham feeding to peak acid output Pentagastrin seemed to provide useful information, in that context. This examination proved to differ from the Hollander test, in that it was harmless to the patient and also provided a better physiological approach to obtaining evidence to postoperative decline of secretion. Significant decline in gastric secretion was postoperatively recorded from 19 patients. Such decline was less strongly pronounced in one patient in whom recurrent ulcer developed together with pyloric stenosis. Induction of merely submaximum vagus stimulation and the need for good cooperation of the patient are considered drawbacks of the sham-feeding test.

Duodenal Ulcer↗
PubMed1983

The role of leukocytes in the serum acute-phase reaction accompanying inflammatory reactions.

The effects of whole-body X-irradiation with a dose of (7 Gray) were studied on the time course of systemic responses (fever, leukocytosis, serum coeruloplasmin concentration) in turpentine-induced inflammation and on the acute-phase reaction (coeruloplasmin, haptoglobin and seromucoid) produced by various stressful conditions (turpentine-abscess, immobilization, restraint conditions). Results showed that in the irradiated animals the lack of the leukocytic and febrile response to turpentine administration was accompanied by a normal coeruloplasmin response. Therefore, we have concluded to the involvement of more than one mediator in the development of systemic reactions accompanying inflammation. The leukopenia induced by whole-body irradiation could not prevent the development or reduce the magnitude of the acute-phase response in any of the models analysed. This observation appears to make doubtful the exclusive role of leukocytes in the mediation of the acute-phase reaction.

Animals↗
PubMed1983

The changed activity of the serum kallikrein-kinin system after ligation of the superior mesenteric artery in rats.

The aim of the experiments was to study the effect of ligation of the superior mesenteric artery on the activity of the kinin-kallikrein system in the plasma and on arterial blood pressure. Ligation of 60 minutes did not change the free kallikrein activity of the plasma, while prekallikrein activity significantly decreased. Blood pressure showed a tendency to increase but not to a significant degree. Five minutes after the release of the ligation (during the period when the functional parameters of the intestinal mucosa returned to normal) free kallikrein activity increased and the arterial blood pressure decreased significantly. A rinse of the intestine with 5 p.c. glucose solution prior to the release of ligation prevents the increase in free kallikrein activity and the fall of blood pressure. The substances absorbed from the bowel lumen and activating the kinin system are probably responsible for the circulation failure following the ligation of the superior mesenteric artery.

Animals↗
PubMed1976

[Is there any decline in the frequency of perforative appendicitis? (AUTHOR'S TRANSL)].

The authors are concluding the letality of appendicitis displays a steadily declining tendency. The rate of perforations observed at their institution corresponds to the average in international surgical literature. They found that letality statistics of appendicitis improved considerably during the last century, whilst perforation percentage has remained practically the same, though the conditions in public health care and possibilities of hospitalization have considerably improved. They expect the number of perforations to decline by establishing the diagnosis even more consistently stage and by performing operations at an early stage, as well.

Adult↗
PubMedDate not supplied

Laparoscopic surgery with carbon dioxide insufflation causes respiratory acidosis.

This study analyzes the changes in cardiopulmonary parameters of patients undergoing laparoscopic cholecystectomy. Six healthy females with normal preoperative cardiopulmonary status were selected for laparoscopic surgery using the same criteria as for traditional cholecystectomy. Respiratory and cardiovascular parameters were collected and compared prior to peritoneal insufflation and just before desufflation. Patients experienced significant elevations of arterial and end-tidal CO2, accompanied by decreased pH. Bicarbonate concentration, blood pressure and pulse rate remained constant. Based on these results, and on our laboratory investigations, we have introduced helium as an alternate agent for insufflation, and present the data from the first two patients so managed. No change was observed in EtCO2, PaCO2 or pH in either of these two patients during the course of surgery. We conclude that hypercarbia occurs in those undergoing laparoscopic cholecystectomy with CO2 insufflation. This acidosis requires compensation by increased minute ventilation to prevent decline in pH. In our initial experience, helium did not produce these changes, and therefore merits further investigation as an alternate agent for abdominal insufflation.

Acidosis, Respiratory↗