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Biomedical subjects

S E Gitlow

Publications and source records attributed to S E Gitlow.

11 recordsLinked to original sources
PubMed1979

Routine reversed-phase high-performance liquid chromatographic measurement of urinary vanillylmandelic acid in patients with neural crest tumors.

A rapid and simple reversed-phase high-performance liquid chromatographic procedure for the determination of vanillylmandelic acid (VMA) is described. This method was applied in the determination of the VMA content in urine from normal subjects and patients with neural crest lesions. Sample preparation is minimal and the analysis is short (20 min) and reproducible. The sensitivity of the UV detection is in the ng range. By this technique, fourteen adult control subjects were found to excrete a mean of 2.86 microgram VMA per mg creatinine, whereas twelve patients with pheochromocytoma excreted a mean of 15.7 microgram VMA per mg creatinine.

Chromatography, High Pressure Liquid↗
PubMed1979

Amniotic fluid uric acid levels determined by reversed-phase liquid chromatography with spectrophotometric and electrochemical detection.

A rapid and precise, reversed-phase high-performance liquid chromatography method for amniotic fluid uric acid is described. Detection of uric acid and other naturally occurring constitutents is based on UV absorption at a wavelength of 280 nm and direct electrochemical oxidation at a potential of +0.800 V. The total analysis time is short (20 min) and the assay requires only filtration of the samples. Uric acid levels were determined in 14 samples of amniotic fluid obtained during the 15th to 24th week of gestation. Results ranged from 0.897 to 4.39 mg per 100 ml of amniotic fluid.

Amniotic Fluid↗
PubMed1979

The disease of alcoholism.

A pharmacological view of narcotic addiction and alcoholism, or sedative addiction, serves as a basis for the further examination of these complex illnesses. The disease called alcoholism (sedativism) consists, however, of much more than just a chronic or periodic addiction to a sedative drug. The urgent need to understand the psychological and societal parameters of this illness is underscored by the likelihood that alcoholism represents the major factor in the cause of death of young adults ( less than 45 years) in the United States today. Its further role as a carcinogen is only recently achieving adequate examination.

Adolescent↗