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Biomedical subjects

S E Poliakov

Publications and source records attributed to S E Poliakov.

8 recordsLinked to original sources
PubMed1992

[Structure of borderline depressive conditions].

Overall 502 workers of a scientific-industrial association were examined in order to study the prevalence and structure of affective disorders. Anxiety appeared the most frequently occurring disorder (289 subjects); depression was revealed in 175, and elements of apathy in 94 persons. In 131 cases, the conditions was assessed as depressive, with the level of depression being subclinical in the majority of them. The structure of depressive disorders, their relation to the demographic characteristics of the examined are considered in detail. The necessity of more active identification and prevention of the " pre-nosological " forms of depression is discussed.

Adult↗
PubMed1992

[Significance of various enzymes of mediator metabolism for evaluation of depression and therapeutic prognosis].

The purpose of the work was to specify the possibilities of the use of the enzymes of mediator metabolism: monoamine oxidase (MAO) of platelets, amine oxidase (AO) of serum and acetyl cholinesterase (ACE) of red blood cells to estimate the structure of depressions and to predict their therapeutic dynamics. 32 patients in the depressive phase of MDP were examined. There were 28 women and 4 men aged 22 to 50 years. The monopolar type was recorded in 28 patients, the bipolar one in 4 (all women). The total disease duration amounts to 0.5-17 years; depression may last from 2 months to 4 years. Depending on the type of the dominant affect the patients were distributed into 2 groups (10 persons had melancholic and 22 anxious depression). It has been shown that activity of platelet MAO and serum AO was significantly higher in anxious than in melancholic depression. An interrelationship was established between activity of these enzymes before treatment and prognosis of the treatment with tricyclic antidepressants. Activation of the enzymes during therapy was parallelled by positive clinical changes. Activity of platelet MAO turned out most significant in terms of prognosis. The data obtained are analyzed from the standpoint of regarding depression as a stressful condition, with the participation of the neurohormonal axis: the hypothalamus, pituitary, and adrenal cortex.

Acetylcholinesterase↗
PubMed1990

[Neurophysiologic changes during the treatment of endogenous depression by reflexotherapy].

Superficial EEG and visual evoked potentials (EP) were studied in 28 patients with endogenous depression treated with reflexotherapy in order to study the neurophysiological correlates of its therapeutic action. A stepwise development of reflexotherapeutic effect was determined. The first stage is that of unspecific activation EEG and EP changes correlating with activating and stimulating clinical effects. At the 2nd stage clinical improvement with proportional reduction of all the components of depressive syndrome run parallel to the normalization of neurophysiological indices.

Acupuncture Therapy↗
PubMed1989

[Psychosomatic correlations in the structure of borderline neurologic and mental disorders].

A total of 544 staff members of the scientific industrial association were subjected to non-randomized examination. The presentation and structure of border-line disorders were studied as correlated to the age, sex, familial status, educational level, occupation, and personality structure. Three groups have been distinguished: (1) conditional norm; (2) neurotic disorders; and (3) affective disorders. Correlations between psychopathological and somatic disorders have been traced in all the groups.

Adult↗
PubMed1988

[The substance of the concept of "phobia"].

As a result of clinico-psychopathological analysis of the structure and mechanisms of development of obsessive phobias and related events, the 3 groups of these are singled out: (1), phobias as the states caused by paroxysmal fear appearing in distinct situations; (2), pseudophobias--the anxious states; (3), phobia-like states caused by various events. Phobias, themselves, are subdivided into 4 species according to the genesis of relevant fear. The differences between these forms are described with the differential diagnostic issues pointed out.

Adult↗
PubMed1987

[Acupuncture in the treatment of patients with endogenous depression].

Acupuncture as an independent method of treatment has been employed in 167 patients with depression associated with manic-depressive psychosis and schizophrenia. It has been established that as judged by the characteristics of psychotropic activity and potency of the antidepressive action this mode of treatment most resembles the administration of balanced antidepressants of the pyrasidol type. Variance, correlation and regression analysis of clinical data has allowed the identification of the predictors of therapy efficacy. The peculiarities of reversed time-course of depressive symptomatology in the process of treatment have also been investigated. The main indications for the therapy have been determined. Acupuncture was found to be effective in some patients showing resistance to antidepressants. The paper presents the results of psychological, biochemical and electrophysiologic examinations of patients in the process of the treatment.

Acupuncture Therapy↗