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Biomedical subjects

S E Stukalov

Publications and source records attributed to S E Stukalov.

At least 19 recordsLinked to original sources

[Experience with the surgical treatment of the sequelae of uveal tract diseases].

The paper describes results of investigation of immunologic reactivity and analysis of outcomes after surgical treatment of patients with chronic anterior uveitis (14 persons), the Fuchs' syndrome (16 persons), pseudoexfoliative syndrome (25 persons) as compared with a control group (50 persons). Immunocorrection of patients with the Fuchs' syndrome was attempted, and analysis of the immunologic status before and after treatment by means of sodium nucleinate immunomodulator and traditional therapy was made. Cataract extraction was performed separately or in combination with sinusotrabeculectomy in case of uveal glaucoma. Immunodeficient syndrome was revealed in patients with chronic uveitis and the Fuchs' syndrome as well as the most severe course of the operation and the postoperative period in patients with chronic uveitis. Considering the important role of immunologic status of the body in the postoperative period, it is recommended to use immunomodulators in a complex treatment of patients with complicated cataract and glaucoma and diseases of the uveal tract.

Adjuvants, Immunologic↗

[A theory on the role of immunologic factors in the pathogenesis of primary glaucoma].

Basing on the literature data and their own clinical, immunomorphologic, and immunochemical findings in glaucoma patients and normal subjects, the authors suggest a concept on the immune factor contribution to the pathogenesis of primary open-angle glaucoma. According to the scheme they suggest, of primary importance in the development of autoimmune reactions in glaucoma are the following factors: changed antigenic specificity of the drainage zone tissues, resultant from involution processes; impaired immune homeostasis, effects of various internal and environmental factors. The pathogenetic role of autoimmune reactions and immunity system regulatory mechanism disorders is explained.

Antibodies, Antinuclear↗