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Biomedical subjects

S E Zolotukhin

Publications and source records attributed to S E Zolotukhin.

At least 19 recordsLinked to original sources
PubMed2005

[Remote results of the treatment of proximal rectal cancer].

There were presented the late results of surgical treatment in 425 patients, suffering upper ampullar and rectosygmoid rectal cancers, to whom transabdominal rectal resection with the duplicature anastomosis formation in 1989--2002 yrs was done. In 93.4% of observations, according to histological investigation data, adenocarcinoma was diagnosed. Concurrent diseases were noted in 226 (53.2%) of patients. The postoperative complications rate was 13.2%, postoperative mortality--2.6%. Late result of treatment was fair.

Adenocarcinoma↗
PubMed2005

[Immediate results of transabdominal rectal resection with the duplicature anastomosis formation].

There were presented immediate results of surgical treatment of 425 patients with the upper ampullar and rectosygmoid portion cancer recti (CR), to whom in 1989-2002 transabdominal rectal resection, using the duplicature anastomosis, was performed. In 93.4% of observations, according to histological investigation data, adenocarcinoma was diagnosed. Concurrent diseases were revealed in 226 (53.2%) patients. The technique of transabdominal CR resection is depicted. There were noted fair immediate results in treatment of the patients: postoperative complications rate have constituted 13.2%, postoperative mortality--2.6%. In structure of postoperative complications purulent-septic one had prevailed, similarly were complications with cardiovascular and respiratory systems affections.

Anastomosis, Surgical↗
PubMed2001

[Treatment of colonic melanoma].

The results of treatment of 5 patients with colonic melanoma are presented. Fine-needle biopsy was used for morphological verification diagnosis. It was established that the patients with colonic melanoma are hospitalized in specialized department, as a rule, with nonopertable tumor. In 1 patient explorative laparotomy was done. Conduction of radical operative intervention was impossible because of presence of multiple metastases in liver. In 4 patients conservative treatment was performed. It was not possible to perform radical operation because of the process spreading. The patients life span after conduction of conservative therapy have constituted 14.5 mo at average.

Colonic Neoplasms↗
PubMed2001

[Restoration of colonic continuity after the Hartmann's surgery].

The intestinal continuity restoration after performance of Hartmann's operation in presence of long rectal stump was done using the method of the duplicature anastomosis formation, which was elaborated in the clinic. The frequency of postoperative complications occurrence was 9.8%: In presence of short rectal stump the colon was descended on perineum via submucosal tunnel in rectal stump according to the method, which was elaborated in the clinic. The frequency of the postoperative complications occurrence was 16.7%. The data presented trusts the expediency of application of the methods elaborated in the clinic for restoration of intestinal continuity after performance of Hartmann's operation in presence of long and short rectal stumps.

Aged↗
PubMed2000

[The use of abdomino-supra-anal resection of rectal cancer].

The results of surgical treatment of 193 patients with upper- and middle ampullar cancer recti, to whom the abdominal supra-anal rectal resection was performed, were summarized. The operation procedure performance was depicted. There were no intraoperative complications. Postoperative complications had occurred in 19 (9.8%) of patients, 3 (1.6%) died. Necrosis of the descended intestine was not noted. The anal sphincter function had restored in 1 mo after performance of operative intervention.

Abdomen↗
PubMed2000

[Resection of rectum and bladder for cancer].

In 1970-1997 period 43 patients with cancer recti, invading bladder, were operated on. The base of surgical tactics was performance of primarily-restorational operation as independent procedure and in the complex of treatment as well. There was noted the fair immediate and late follow-up result of treatment.

Adult↗
PubMed2000

[Intensive therapy and strategy of management of patients with rectal cancer after the colonic descending to the perineum].

Optimal tactic for management of the patients on various stages of treatment was elaborated together with surgical procedure, basing on the experience of 3500 operations conduction for cancer recti, mainly abdominal resection with colon descendant to perineum. Methods of preoperative preparation and anesthesiological support were stated as well as the tactics of postoperative management of patients.

Colorectal Neoplasms↗
PubMed2000

[The restoration of colonic continuity after Hartmann's operation].

The experience of restorational intervention with formation of duplicature (invagination) anastomosis after Hartmann's operation in 45 patients with complicated cancer recti and colonic cancer was summarized. Complications had occurred in 9.8% of observations, one patient died.

Anastomosis, Surgical↗
PubMed2000

[Methods of inversion closure of transient colostomy].

The method of inversive excision of colostomy, securing access to noninflamed tissues of intestine and pericolostomic region for consequent suturing made in accordance to requirements. While using the method purulent-inflammatory complications had occurred in less than 5% of patients and insufficiency of anastomotic sutures--in 3.4%.

Adult↗
PubMed2000

[Modern aspects of treatment of colonic cancer, complicated by ileus. Part II. Treatment of colonic cancer, complicated by ileus].

The results of treatment of 364 patients with colonic cancer, complicated by ileus. In 165 patients with partial ileus the radical operative interventions were performed, palliative--in 61 and symptomatic--in 83; with complete ileus--in 30.9 and 16 patients accordingly. Application of the interintestinal anastomoses formation methods, elaborated in the clinic, had permitted to perform primarily-restorational operations in 81.9% of patients with partial ileus and in 61.5%--with complete one, obtaining satisfactory immediate results. Insufficiency of the duplicature anastomosis sutures had occurred in 5 (2.2%) of colonic cancer patients, suffering partial ileus.

Colonic Neoplasms↗
PubMed1998

Comparative evaluation of the complex treatment of rectal cancer patients (chemotherapy and X-ray therapy, Ukrain monotherapy).

A total of 48 patients suffering from rectum cancer were included in this randomized study conducted at the Proctology Department of the Donetsk Regional Anti-Cancer Center. Patients in group I (24 patients) received an intensive course of high fractional X-ray therapy (cumulative dose up to 25 Gy) with direct protracted endolymphatic chemotherapy with 5-fluorouracil (5-FU) instilled in 600 mg/m2 each day before operation, up to a cumulative dose of 5 g. The 24 patients in group II were treated with Ukrain as monotherapy, 10 mg each second day before operation (up to a cumulative dose of 60 mg) and a total of 40 mg after surgical intervention. Repeated Ukrain courses (100 mg/per course) were also given 6 months after surgical operation. In each ease preoperative treatment was followed by routine surgical operation. Prolongation morbi were found to have developed 14 months later in six patients in group I (25.0%), whereas in group II they were found only in two cases (8.3%). Comparative investigation of objective and subjective signs, analysis of results of instrument and X-ray data, as well as dynamic study of the histological structure of rectal tumors, indicate that Ukrain exerts a more potent malignotoxic and immunomodulating action than other types of anticancer treatment.

Adult↗