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Biomedical subjects

S Elwany

Publications and source records attributed to S Elwany.

At least 37 records · Page 2Linked to original sources
PubMed1987

Ultrastructural observations on vasomotor rhinitis.

The ultrastructure of the respiratory nasal mucosa of patients suffering from vasomotor rhinitis was studied and compared with the reported ultrastructural findings in cases of chronic perennial allergic rhinitis. The principal ultrastructural differences were the absence of interendothelial gap junctions, the scarcity of eosinophils and plasma cells, and the absence of immunologically stimulated or degranulated mast cells in vasomotor rhinitis. These differences were discussed in the light of the known pathophysiologic facts.

Biopsy↗
PubMed1986

Pneumatic nasal catheters: advantages and drawbacks.

The authors present their experience with pneumatic nasal catheters in cases of epistaxis. Among the advantages of this method over tamponade with petroleum jelly-covered gauze are: Effective tamponade without causing hypoxia, carbon dioxide retention or additional loading of the cardiopulmonary system; Less need for sedation; and Easy application and removal. Conversely, its most important adverse effect is the possibility of pressure necrosis of the nasal mucosa and nasal septum. This can be greatly reduced by considering a few technical recommendations.

Adult↗
PubMed1986

Hearing and middle ear function in rheumatoid arthritis.

The hearing and middle ear function in 68 patients with rheumatoid arthritis were tested. Reduced middle ear compliance, presumably due to stiffening of the tympanossicular chain, was noted in 48 patients (70.50%). Conductive hearing loss and absence of the stapedius reflex, were recorded in only one patient (1.40%). In 20 patients (29.40%) a moderate (20-30 dB) high frequency sensorineural hearing loss was found. The results of loudness balance and tone decay tests and the speech discrimination scores suggested cochlear pathology in some cases. However the multiplicity of factors that might be involved in sensorineural hearing loss, and the absence of a significant relation between such a loss and the activity of the disease or drugs used in its treatment makes the postulation of a plausible explanation a difficult, still unfinished task.

Arthritis, Rheumatoid↗
PubMed1985

Radiological findings in lipoid proteinosis.

The radiological findings in six patients suffering from lipoid proteinosis have been described and discussed. Laryngeal examination showed thickened epiglottis, swollen arytenoids and aryepiglottic folds, thickened irregular false and true vocal cords, and increased stiffness of the vocal cords. The ventricles and subglottic region were free. Bean-shaped suprasellar calcifications were found in two cases who were free of neurological symptoms. The chest and upper gastro-intestinal tract were radiologically free.

Adolescent↗
PubMed1985

Delayed ultrastructural radiation induced changes in the human mesotympanic middle ear mucosa.

The irradiation-induced changes in the middle ear mucosa of six patients were described and discussed. The epithelium showed marked reduction of the cytoplasmic mass, variable degrees of ciliary loss and widening of the intercellular spaces with disruption of some of the maculae adherentes. The connective tissue stroma showed increased production of collagenous fibrous tissue and increased number of synthetically active fibroblasts. New gland formation has been observed and the glands exhibited reduced activity. The endothelial cells of some blood capillaries were swollen and the basal lamina was duplicated. The lumina of other capillaries were completely obliterated and replaced by a cord of fibrous tissue.

Capillaries↗
PubMed1985

Histochemical study of cartilage autografts in tympanoplasty.

Histochemical examination of lactic dehydrogenase enzyme activity was used to detect the effect of certain factors on the viability of cartilage autografts in the middle ear. The study shows that the presence of perichondrium on both sides of the strut and placing the lateral end of the strut increase the chance of survival of chondrocytes. On the other hand, middle ear infection has a very bad effect on the viability of chondrocytes. The length of the strut and the presence of silastic film in the middle ear have been found to be unimportant as far as the survival of the graft is concerned.

Animals↗
PubMed1985

Relevance of the conventional Waters' view in evaluating chronic bacterial maxillary sinusitis.

Considerable controversy exists as to whether X-ray examination of the sinuses is a reliable diagnostic guide or not, in cases of chronic bacterial maxillary sinusitis, as many factors apart from infection in the sinuses may produce radiographic signs on the X-ray film. With those facts in mind, it was decided to investigate the diagnostic reliability of Waters' view in these cases. The present work showed that radiographic signs of chronic maxillary sinusitis have different diagnostic and predictive reliabilities ranging from the almost complete inaccuracy of reduced translucency or 'veiling' of the sinus to the perfect validity of 'fluid levels' or polyps within the sinus. In general, while Waters' view undoubtedly yields valuable information regarding maxillary sinus pathology, nevertheless the presence of various sources of error while exposing and reading the film should make one appreciate that radiographic diagnosis is not absolute and should only be considered in the light of the clinical findings and possibly other investigations.

Adolescent↗
PubMed1985

Brain stem auditory evoked potentials in patients with the lateral medullary (Wallenberg's) syndrome.

The purpose of this study is to investigate the diagnostic value of using brain stem auditory evoked potentials (BSEP) in patients with the lateral medullary (Wallenberg's) syndrome. The observed changes included: prolongation of the interpeak latency intervals from wave I to V and III to V; prolongation of the interaural latency difference for wave V; splitting or absence of wave III, and the presence of a broad partly fused wave III-V complex. The present study showed that BSEP can be used to confirm the diagnosis of this syndrome and ascertain the site of the lesion.

Brain Stem↗
PubMed1984

The human respiratory nasal mucosa in females using contraceptive pills. An ultramicroscopic and histochemical study.

The ultrastructure and histochemical changes in 25 females using contraceptive pills were studied. Fifteen pill-using females developing no nasal symptoms showed similar changes to those observed in symptom-free pregnant females. Ten pill-using females developing nasal symptoms showed squamous metaplasia, interepithelial oedema, glandular hyperplasia, histiocytic proliferation and fibrous tissue deposition, all attributed to the action of oestrogen. Their histochemical reactions were similar to those of chronic hypertrophic non-allergic rhinitis.

Adult↗
PubMed1984

Further observations on nasal mucosal changes in scleroderma. A histochemical and electron microscopic study.

The respiratory nasal mucosa of patients with scleroderma showed several ultrastructural and histochemical changes. These included initial goblet cell hyperplasia, loss of cilia and microvilli, exfoliation of the superficial epithelial layers, increased glandular activity in cases with squamous metaplasia and fibrous tissue deposition in the lamina propria. These changes seem to be related to the duration of the disease, whose nature and pathogenesis are still uncertain.

Adult↗
PubMed1983

The effects of topical dinoprostone on the nasal vasculature. A study of patients with allergic rhinitis.

We studied the effects of topical dinoprostone on the nasal blood vessels of patients with allergic rhinitis. The outstanding changes noted were constriction of the arterioles and capillaries (to a lesser extent) and tight closure of the interendothelial junctions. These changes caused a diminution of nasal blood flow and edema fluid formation, a reduction in the size of the turbinates, and consequently, an increase in nasal patency. However, dinoprostone had no effect on the nasal venules.

Administration, Topical↗
PubMed1983

Surgical anatomy of the sphenoid sinus.

In recent years the trans-sphenoidal approach to the pituitary gland has come into vogue and a study of the surgical anatomy of the sphenoid sinus has become increasingly important in order to avoid many surgical mishaps. Moreover, the sphenoid sinus has complicated relationships and its diseases may and do give rise to a complexity of symptoms. The anatomy of the sphenoid sinus has been described by Ridpath (1947), Dobromylsky and Scherbatov (1966), Davies and Coupland (1967), Simpson et al. (1967), Montgomery (1972), Last (1972), Ballenger (1977), Hamilton and Harrison (1979), and Davies (1980). The present work was designed to study the anatomy of the sphenoid sinus and its surgical applications. Particular attention was focused on the relationships of the sella turcica to the sphenoidal sinuses.

Adult↗
PubMed1983

Ceruminous glands in otosclerosis. A histopathological and histochemical study.

The ceruminous glands of the external auditory canal skin of 20 patients suffering from otosclerosis were examined histologically and histochemically. The histological changes included flattening of the lining cells and widening of the lumina of the glands. Histochemical alterations were in the form of diminished succinic dehydrogenase, alpha esterase and alkaline phosphatase enzyme activities. The histological and histochemical changes indicated that atrophy of the ceruminous glands with diminished wax production occurred in some otosclerotic patients. This atrophy may be secondary to the involvement of the ground substance, vessels and nerves of the external auditory canal by the same etiologic factor responsible for the pathogenesis of the otosclerotic process.

Cerumen↗
PubMed1982

The human respiratory nasal mucosa in pregnancy. An electron microscopic and histochemical study.

The ultrastructural and histochemical changes in the respiratory nasal mucosa of thirty pregnant females have been studied. Symptoms-free pregnant females, regardless of the duration of pregnancy, showed glandular hyperactivity, increased phagocytic activity, and increased amount of acid mucopolysaccharides in the ground substance. These changes have been suggested to be due to the rise in the levels of female sex hormones during pregnancy. Pregnant females developing nasal symptoms during pregnancy have been proved by electron microscopy and histochemically to be allergic in origin. This allergy, being not due to the hypersensitization of the patient's own sex hormones, may be due to any of the factors previously mentioned.

Adult↗
PubMedDate not supplied

Histologic and histochemical study of effects of anabolic steroids on the female larynx.

The larynges of 30 unmated, mature female albino mice were examined histologically and histochemically after injecting them with 19-nandrolone phenylpropionate. Permanent irreversible changes, in the form of parakeratosis and squamous metaplasia of the epithelium, and hypertrophy of the muscle fibers, were observed together with persistence of increased alkaline phosphatase enzyme intensity in the endothelium of capillaries and increased activity of nonspecific esterase in the muscles. Similar changes may be responsible for the alteration in the human female's voice after prolonged treatment with anabolic steroids.

Anabolic Agents↗
PubMedDate not supplied

Radiofrequency bipolar submucosal diathermy of the inferior turbinates.

Fifty nonatopic patients with chronic hypertrophic rhinitis and suffering from chronic nasal obstruction due to hypertrophied inferior turbinates were subjected to bipolar submucosal diathermy using a radio frequency unit and a bipolar turbinate probe. One year postoperatively, 76% of patients showed significant improvement of their nasal breathing and another 16% reported partial improvement. The minimal cross sectional has also significantly increased from 0.58 +/- 0.05 cm2 to 0.72 +/- 0.04 cm2 and the decongestive effect was statistically significant. Electron microscopic examination of the nasal mucosa at the end of the follow up period revealed intact healthy epithelium as well as intense fibrosis of the underlying stroma. The results of the work showed that bipolar submucosal diathermy is a safe, effective outpatient procedure that does not require nasal packing or expensive instrumentation. The procedure can be repeated, if necessary, according to the patient's needs.

Biopsy↗