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S Enomoto

Publications and source records attributed to S Enomoto.

At least 217 records · Page 12Linked to original sources
PubMed1981

Synaptic basis of orbital cortically induced rhythmical masticatory activity of trigeminal motoneurons in immobilized cats.

Synaptic basis of the centrally induced masticatory rhythm was studied by intracellular recording from jaw closer and opener motoneurons during repetitive stimulation of the orbital gyrus (OG) of the encéphale isolé of immobilized cats, with the following results. (1) Repetitive OG stimulation induced a rhythmical alternation of hyperpolarizing and depolarizing potentials in jaw closer motoneurons. Rhythmical efferent burst discharges induced in the digastric nerve by OG stimulation coincided with the hyperpolarizing phase. The hyperpolarizing potential was reversed to a depolarizing potential by intracellular Cl- injection, while the depolarizing potential was not reversed to hyperpolarization, indicating that the hyperpolarizing and depolarizing potentials consisted at least mainly of IPSPs and EPSPs, respectively. (2) Repetitive OG stimulation induced rhythmical depolarizing potentials superimposed by spike bursts in jaw opener motoneurons, corresponding in time with the rhythmical efferent bursts in the digastric nerve. Synaptic activation noise was increased coincidentally with the depolarizing potential, indicating that EPSPs were involved in the generation of the depolarizing potential. No or little hyperpolarization if any was observed between successive depolarizing potentials. (3) Repetitive OG stimulation induced efferent burst discharges in the digastric nerve with the masticatory rhythm unaccompanied by any spike potential in the supratrigeminal neurons responsible for peripherally evoked inhibition of jaw closer motoneurons, indicating that the peripheral inhibitory mechanisms do not play an essential role in the central generation of the masticatory rhythm by OG stimulation.

Animals↗
PubMed1980

The role of medial bulbar reticular neurons in the orbital cortically induced masticatory rhythm in cats.

Single unit activity was recorded from medial bulbar reticular neurons, which responded with spike potentials to stimulation of the orbital gyrus, in immobilized cats. Neurons were found which showed rhythmical bursts corresponding to the orbital cortically-induced masticatory rhythm. Using spike-triggered averaging technique, some of these reticular neurons were suggested to be inhibitory neurons projecting to jaw closer motoneurons and to participate in the inhibitory phase of these motoneurons during the centrally generated masticatory rhythm.

Animals↗
PubMed1979

Syndrome of the sea-blue histiocyte--the first case report in Japan and review of the literature--.

A case of the syndrome of sea-blue histiocyte is presented in a 53-year-old Japanese woman, which is the first recorded case in Japan. The patient had hepatosplenomegaly, bleeding manifestations, mild thrombocytopenia, fatty metamorphosis and cirrhosis of the liver, as well as abnormal serum lipid profiles. Her parents were consanguineous and her maternal grandmother with hepatomegaly died of hepatic failure. Histologically, peculiar histiocytes containing numerous, intracytoplasmic sea-blue stained granules on May-Giemsa stain were demonstrated in biopsy materials of the bone marrow, lymph node and liver. The sea-blue granules in these histiocytes proved to have histochemical staining characteristics of lipogenic ceroid-like pigment. Ultrastructurally, these granules showed membrane-bound, pleomorphic inclusions of heterogeneous nature, including electron-dense amorphous or variegatedly osmiophilic, frequently laminated materials. Enzyme cytochemically, localization of acid phosphatase activity was demonstrated in and around the intracytoplasmic inclusions. With regard to the pathogenesis of the sea-blue histiocytes in this case, it may be suggested that the existence of the abnormality in lipid metabolism plays an important role in intralysosomal ceroidogenesis in these histiocytes.

Acid Phosphatase↗