PubMed Health⌕ Search

Biomedical subjects

S Eren

Publications and source records attributed to S Eren.

At least 37 records · Page 2Linked to original sources
PubMed1999

Haemangiopericytoma of the middle ear with benign histological features.

Haemangiopericytoma is a rare vascular tumour, particularly in the head and neck region. We described the first case of haemangiopericytoma arising from the middle ear in 1995. The present case is the second example of a primary middle-ear haemangiopericytoma with benign histological features. Clinical photography, computed tomography (CT) and magnetic resonance imaging (MRI) scans and histological photographs depict the findings.

Ear Neoplasms↗
PubMed1999

Efficacy and safety of rectal thiopental: sedation for children undergoing computed tomography and magnetic resonance imaging.

PURPOSE: We evaluated the clinical safety, effectiveness, efficiency and potential side effects of rectally administered thiopental in 30 children undergoing computed tomography (CT) and magnetic resonance imaging (MRI). METHODS: The doses of thiopental used were 50 mg/kg for infants under 6 months of age, 35 mg/kg for infants between 6 and 12 months of age and 25 mg/kg for older children. After administration of the sedative, oxygen saturation was continuously monitored and vital signs were recorded every 20 min during the imaging procedure and then every 20 min until discharge. RESULTS: Successful sedation and adequate imaging were obtained in 29 of 30 (96.7%) patients. Respiratory depression was not observed in any patient. However, oxygen saturation dropped below 90% transiently (to 88%) in three patients (10.0%) and this was immediately corrected by repositioning the child's neck to open the upper airway. All successfully sedated patients were asleep within 15 min (mean +/- SD 7.3 +/- 2.7 min) and sedation was sufficient for at least 30 min. Prolonged sedation was observed in two patients. CONCLUSIONS: We believe that rectal thiopental is a safe, effective and efficient form of sedation for pediatric imaging.

Administration, Rectal↗
PubMed1995

Perineal ultrasonography in postoperative assessment of two different surgical procedures for stress urinary incontinence.

Thirty-eight incontinent and 57 continent patients who had undergone MMK urethropexy and anterior colporrhaphy procedures were examined by perineal ultrasonography. Bladder neck hypermobility was described with ventrodorsal and cephalocaudal directional parameters. In the incontinent patients both cephalocaudal and ventrodorsal mobilities were found to be significantly greater compared to the continent group, the latter ultrasonographic parameter being relatively more significant (P < 0.01 and P < 0.001, respectively). In surgically cured patients who underwent the MMK procedure both ventrodorsal and cephalocaudal mobility had been significantly limited in contrast to their incontinent counterparts; but these differences had been detected only in ventrodorsal mobility by the anterior colporrhaphy procedure.

Female↗
PubMed1995

Assessment of microcirculation of an axial skin flap using indocyanine green fluorescence angiography.

In many cases the complexities of skin-flap microcirculation are difficult to assess despite all the subjective and objective examination techniques available today. Adequate microcirculation is essential for tissue viability, so any method employed for studying microcirculation should provide as accurate an assessment of the prevailing conditions as possible. Of all the clinical methods, the fluorescence technique using the dye sodium fluorescein has so far provided the most reliable results. However, the pharmacokinetic properties of this tracer have prevented the technique from becoming established in clinical practice. The fluorescent dye indocyanine green (Cardio Green), on the other hand, has far more favorable pharmacokinetics. In an experimental animal model, the fluorescence technique using indocyanine green (indocyanine green angiography, ICGA) was used to study postoperative changes in the microcirculation of a skin flap. On the day of operation, indocyanine green angiography revealed a state of hemodynamic imbalance for which the organism was able to compensate in the postoperative phase with the aid of humoral, physical, and metabolic factors. With indocyanine green angiography it was possible to quantify objectively the new hemodynamic equilibrium. Basically, microcirculation may be quantified in temporal and spatial terms. The significant objectivity of indocyanine green angiography and short intervals between each examination favor its possible and meaningful use in clinical practice and give cause for continuing studies.

Angiography↗
PubMed1995

[Objective evaluation of the microcirculation in the skin with indocyanine green angiography (ICGA). A method for the clinic?].

In some cases, assessment of the microcirculation of tissues can be very difficult. Various methods have been proposed for evaluating microcirculation, none of which has so far established itself for clinical use. Indocyanine Green Angiography (ICGA) is a suitable and objective method for quantifying microcirculation and due to the pharmacocinetic properties of this dye the prospects for clinical application of this fluorescence technique are rather promising. In an experimental animal study, postoperative changes of microcirculation were examined in a skin flap. The day of operation, ICGA showed pathophysiologic changes of the microcirculation which was corrected during the postoperative phase. This new state of haemodynamic equilibrium was objectively quantified by ICGA. The objectivity and repeatability within short time intervals speak for clinical application after adequate development and experience. The indication has to be clarified in each case. Rare incidence of negative reactions should be kept in mind.

Animals↗
PubMed1994

Infrared videoangiofluorography of the skin with indocyanine green--rat random cutaneous flap model and results in man.

We report a new technique for visualizing and measuring skin perfusion on a macroscopic scale using low doses of indocyanine green (0.3 mg/kg body weight). The method was first evaluated in the rat random cutaneous flap model and subsequently applied to determine skin perfusion in a patient with peripheral arterial occlusive disease (PAOD), a patient with forefoot necrosis due to diabetic microangiopathy, and a healthy volunteer. The observed kinetics of fluorescence appearance could only be explained by transition of the dye to a third compartment different from the blood plasma and having a greater affinity for indocyanine green. In PAOD reduced skin perfusion in the tissue surrounding the arterial ulcer could be clearly demonstrated, whereas skin perfusion in diabetic microangiopathy seems to be unaffected. Other potential clinical applications for the technique in dermatology and vascular and reconstructive surgery are briefly discussed.

Adult↗
PubMed1993

Total scalp replantation based on one artery and one vein.

A successful replantation of a totally avulsed scalp, including both eyebrows, with only one arterial and one venous anastomosis to the superficial temporal vessels is described. Apart from a small partial skin necrosis of the right eyebrow, the entire transplant survived. Subsequently, the patient required only minor additional skin grafting, correction of scars with a skin expander, and reconstruction of the eyebrow with hair micrografts. Replantation of the total scalp based on two or more vessels has previously been recommended and reported elsewhere. In the present case, complete survival of the scalp on only one artery and one vein was demonstrated, indicating that replantation should be considered even if available vessels for anastomosis are minimal.

Adult↗
PubMed1993

Possible involvement of eicosanoids in alpha-naphthylthiourea-induced pulmonary oedema and alteration of angiotensin-converting enzyme activity.

alpha-Naphthylthiourea (ANTU) when injected intraperitoneally to rats at a dose of 10 mg/kg elicited lung oedema indicated by an increase in lung weight/body weight (LW/BW) ratio and pleural effusion. The injection of acetylsalicylic acid, which is a cyclo-oxygenase inhibitor, and BW 755C, a cyclo-oxygenase and lipoxygenase inhibitor, prior to ANTU produced a significant inhibition in pleural fluid accumulation without changing the LW/BW ratio. BW A4C, a selective 5-lipoxygenase inhibitor, however, caused a highly significant inhibition in pleural effusion and a slight but significant decrease in LW/BW ratio. Thromboxane A2 synthetase inhibitor, UK 38485, caused a slight but significant inhibition in pleural fluid accumulation without altering the LW/BW ratio. Iloprost, however, produced a slight but significant inhibition in the LW/BW ratio without reducing the pleural effusion rate. A significant decrease in angiotensin-converting enzyme (ACE) activity in the isolated perfused lungs of ANTU-treated rats was noted. This observation was thought to be an evidence of a functional alteration of the lung vascular endothelium. The possible role of eicosanoids in lung oedema induced by ANTU and the related mechanisms of decreased ACE activity are discussed.

Animals↗
PubMed1993

[Free, vascularized, folded fibula transplantation].

A free vascularized folded fibula as possibility for reconstruction of segmental bony defects up to 9 cm is described. Preserving its vascularisation, the fibula is osteotomized and folded into two equal or two vascularized bone transplants of different length with only one arterial and venous pedicle. Folding of the fibula leads to a biomechanically superior stabilisation. This technique was used in a posttraumatic osteomyelitic defect of the tibia after a Pilon tibiale fracture.

Adult↗
PubMed1993

[Herpes paronychia].

Herpetic whitlow is a rare viral infection, that should be treated nonoperatively and managed by a hand surgeon. There is a high risk of infection for dentists and other medical personal. The authors present a case, describe findings, possible complications, and treatment.

Animals↗
PubMed1992

Indication, technique, and results of plantaris medialis neurovascular island flaps.

Treatment of soft tissue defects in the heel often causes problems because of the anatomical structures of the foot and the foot's function in bearing the entire weight of the body. Various types of flap surgery have been tried, to deal with these problem areas. As ever, all the skin flaps lacked the normal quality of the plantar skin, which has fibrous septa with reduced flexibility. In view of the quality of the skin and subcutaneous tissue and the quality of the nerve supply, the technique of neurovascular island flaps for the plantaris medialis was used over the last 4 years in 14 patients, to conceal small to medium-sized heel defects. In this report, we examine anatomy, indication, technique, and results with regard to plantaris medialis island flaps. Their use is discussed in comparison with other types of flaps already used in this region.

Adolescent↗
PubMed1990

[Primary and secondary soft tissue injuries of the hand and therapeutic possibilities].

Primary treatment of soft tissue hand injuries is most important for further management and progress. It ensures best protection of lower structures. Soft tissue lesions that can not be closed without resulting tensions need instant plastic-surgical therapy. Various possibilities that range from split skin flaps to distant flaps with microvascular anastomosis can be chosen to cover primary as well as secondary soft tissue defects.

Hand Injuries↗
PubMed1989

[Burns. Primary management and clinical therapy].

Following the saving of the patient in addition to the cool-water therapy an adequate infusion therapy with Ringerlactate should be initiated immediately. For the transport the wounds should only be covered sterile; in case of inhalation trauma early intubation. Adults with burns of more than 15% TBA (children already at 5%) as well as with burns of hands and face require an immediate transfer into a burncenter. After cleansing of the wounds in the hospital estimation of the burn depth and decision of treatment. Deep burns of hand and face should be necreted and covered within the first 72 hours if possible. For the remaining deep burns one should try a primary excision too or in case of a bad general condition a delayed primary excision after tanning. Up to the moment of operation one should choose between an open, half open or closed treatment. The covering of the necrectomized areas is done temporary with alloplastic material or xeogenic or allogenic skin respectively. Definitive covering can only be achieved by autogenic split skin or intermingled skin grafting. New possibilities are offered by "in vitro" grown keratinocytes.

Adult↗
PubMed1989

[The diagnostic significance of disordered gas exchange in inhalation trauma].

52 patients with burn injuries were prospectively investigated. In all cases intubation was necessary because of clinical signs of smoke inhalation. We studied whether a correlation could be established between the clinical signs and bronchoscopic findings and the degree of gas exchange disorder. The disturbed oxygenation was defined by the average alveolo-arterial oxygen quotient of the first 24 hours. The inhalation injury was classified by clinical signs and bronchoscopic findings (inhalation injury score). The average alveolo-arterial O2-quotient of the first 24 hours and the inhalation injury score showed a high correlation coefficient (r = 0.77). No correlation was seen between the severity of gas exchange disorder and the amount of burned body surface area (r = 0.20) respectively the age of the patients (r = 0.27). According to these results early onset of disorders in gas exchange after burn injury reflects smoke inhalation. Therefore the gas analysis from arterial blood can be a very helpful diagnostic method and allows to estimate the degree of pulmonary damage by inhalation injury.

Adolescent↗
PubMed1987

[Doppler sonography alone in the preoperative planning of free flap transplantations].

Successful transplantation of a free flap is dependent on a thorough knowledge of the circulatory conditions of the donor and the recipient sites. The Allen-test is not feasible in all cases and is not always dependable. Angiography is not only a strain for the patients but often involves risks. This paper gives an account of the Doppler-sonography investigation method based on documented studies of the radial and ulnar arteries and of the anterior and posterior tibial arteries. This method involves no strain on the patients and allows for precise assessment of the circulatory conditions of the donor and recipient sites.

Forearm↗
PubMed1983

[Reposition of old dislocations or dislocation fractures of the carpal bones using Wagner's distraction apparatus].

In treatment of old traumatic dislocations and fracture dislocations of the carpal bone complex, a careful and exactly dosed pre-extension of the shrunken capsular ligaments can be obtained by the use of Wagner's distraction apparatus. The pre-extension procedure is followed by open or closed reposition. The surgeon's movements are not hindered. Sterile draping of the operating field can easily be performed in contrast to other methods of reposition like hanging up the forearm with a counter-weight or olecranon-metacarpal extension with counter-traction. Up to 10 months after volar dislocation of the lunate bone the destructed carpal vault could be reconstructed.

Bone Screws↗