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Biomedical subjects

S Eykyn

Publications and source records attributed to S Eykyn.

10 recordsLinked to original sources

Co-trimoxazole in prevention of bacteriuria after prostatectomy.

In a prospective, double-blind trial prophylactic cotrimoxazole produced a highly significant reduction in the incidence of bacteriuria after prostatectomy. Only two out of 38 patients who received the drug developed bacteriuria compared with 19 out of 36 patients on placebo. Klebsiella-Enterobacter spp and coagulase-negative staphylococci were responsible for most infections. Although co-trimoxazole prophylaxis is obviously effective, widespread use might increase the incidence of bacterial resistance.

Aged

Staphylococcus aureus transmitted in transplanted kidneys.

Staphylococcus aureus septicaemia developed shortly after transplantation in both recipients of transplanted kidneys from a donor who had received electrical burns. In each case the organism appeared initially in the urine. All staphylococci isolated were phage type 6/47/54/75. Transplant nephrectomy was necessary in both recipients because of complications of infection, and one recipient died. These results draw attention to the possible significance of Staph. aureus in the urine of recipients after transplantation and to the potential risk of transplanting kidneys from a burned donor.

Adult

Urinary tract infection following trans-rectal biopsy of the prostate.

An unacceptably high incidence of urinary tract infection was found in a retrospective survey of patients undergoing trans-rectal biopsy of the prostate. The incidence was considerably greater than that found in a prospective survey of bladder endoscopy alone. It is suggested that preoperative antibiotic prophylaxis might be worthwhile in this situation.

Anti-Bacterial Agents