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Biomedical subjects

S F Avery

Publications and source records attributed to S F Avery.

6 recordsLinked to original sources
PubMed2005

Spontaneous calcific cerebral embolus.

Spontaneous calcific cerebral embolus is a rare complication of calcific vascular disease such as calcified aortic plaques, and calcific aortic and mitral stenosis. Fewer than 10 case reports are described in the literature. Cerebral ischaemic symptoms may provide the indication for surgical replacement, even in the absence of valvular insufficiency or stenotic symptoms. We report a case of stroke in a young man with a known bicuspid calcific aortic valve.

Adult↗
PubMed1990

Eaton-Lambert myasthenic syndrome: two cases with typical and atypical features.

Eaton-Lambert myasthenic syndrome is a rare disorder of neuromuscular transmission. We are unaware of previous New Zealand reports and present two patients. Characteristic abnormalities in compound muscle action potential amplitude following repetitive nerve stimulation and on single fibre electromyography were present. Both patients also showed mild patchy abnormalities in peripheral nerve conduction. The clinical picture resembled Guillain-Barre syndrome in one patient who developed severe generalised weakness and respiratory failure. In both patients the neurological presentation lead to the recognition of a previously asymptomatic small cell lung carcinoma.

Aged↗
PubMed1989

Pituitary apoplexy.

Pituitary apoplexy, a rare neurological emergency resulting from pituitary haemorrhage or infarction, should be considered a possibility in patients presenting with headache. Six cases are reported. The patients, four females and two males, ranged in age from 18 to 53 years. In only two had pituitary pathology previously been recognised. Headache occurred in all patients, visual field defects in four, ocular paresis in two, and subsequent hypopituitarism in five. The headache type suggested intracranial catastrophe in only one patient. A possible precipitant was noted for three of the episodes, including, in one patient, salmonella gastroenteritis. Cortisol deficiency during the acute event was common. Semi-urgent surgery was performed in two patients. In two others, prompt resolution of symptoms occurred following administration of dexamethasone.

Acute Disease↗
PubMedDate not supplied

Prostaglandin synthesis and oedema formation during reperfusion following experimental brain ischaemia in the gerbil.

Regional brain tissue prostaglandin (PG) levels have been measured during ischaemia produced by bilateral carotid occlusion for 1 hour and following restoration of flow. In the normal gerbil, the frontal cortical levels of PGF2 alpha were: 6.7 +/- 1.3 pg/mg and for PGE2: 6.4 +/- 1.1 pg/mg of brain tissue protein. Following 1 hour of ischaemia PGF2 alpha rose to 50.4 +/- 8.3 pg/mg whilst there was only a slight rise in PGE2 (10.7 +/- 1.6 pg/mg). Post ischaemic values for parietal and occipital areas were somewhat higher, but showed the same trend. Within 15 minutes of the restoration of flow there was a massive increase in PGF2 alpha levels which reached a peak at 2 hours (300 pg/mg) and then subsided to control values. PGE2 levels did not change for the first 30 minutes of recirculation, but then rose for the rest of the period of observation. The pattern of cytotoxic oedema resembled PGF2 alpha closely while the Evans blue staining (vasogenic oedema) was similar in time to the PGE2 pattern.

Animals↗