PubMed Health⌕ Search

Biomedical subjects

S F Garagan

Publications and source records attributed to S F Garagan.

12 recordsLinked to original sources
PubMed1998

[Clinico-instrumental and pathologicoanatomic comparisons in diabetic cardiopathy and ischemic heart disease in diabetics].

46 patients with diabetes mellitus (DM) of both sexes under 40 years of age in the state of compensation were found to have significantly greater figures (1, 3) for the parameter characterizing the subendocardial bloodflow, obtained by calculating technique, versus 33 DM patients beyond 40 in the state of compensation, which fact suggests the presence of diabetes macroangiopathies (IAD) in the latter. In 6 patients the diagnosis of IHD has been verified postmortem.

Adult↗
PubMed1990

[Gouty heart defects].

The authors revealed heart failure in 7 of 216 patients with gout. Two of them showed isolated mitral valve insufficiency and two patients aortal insufficiency while combined aortal disease, combination of mitral and aortal insufficiency and combined mitral valve disease with aortal insufficiency occurred each in 1 patient. One could not find distinct dependence between the clinical variant of the course of gout and development of a definite heart failure. Clinical and electrocardiographic signs of the revealed kinds of cardiac abnormalities are described. The morphological changes of the valves are described on the basis of 2 autopsy cases. The possible mechanism of development of podagric heart failures is discussed.

Adult↗
PubMed1990

[The differential diagnosis of diabetic cardiopathy and ischemic heart disease in diabetics].

The author examined the subendocardial blood flow in 79 patients with diabetes mellitus (II, II-III degree of decompensation) before and after traditional treatment. The diastolic, terminal-diastolic and average-diastolic pressures were reduced, the diastole ejection period of the left ventricle and vitality index of the myocardium were increased and were more pronounced in patients under 40 years of age after treatment indicating absence of IHD and marked atherosclerosis of the coronary arteries.

Adult↗
PubMedDate not supplied

[Central hemodynamics, effectiveness of endocardial blood flow and general physical work capacity in impaired glucose tolerance and diabetes mellitus].

The end diastolic pressure, myocardial viability index and other parameters of myocardial contractility, as well as central hemodynamics and general physical working capacity were studied in 120 subjects, including 20 subjects with impaired glucose tolerance, 80 patients with diabetes mellitus, and a control group of 20 healthy subjects. In impaired glucose tolerance, a tendency to reduced endocardial blood flow and myocardial contractility as well as elevated end diastolic pressure were observed. The physical working capacity remained within normal. In decompensated diabetes mellitus, the efficacy of endocardial blood flow considerably reduced, the end diastolic pressure rose more than twofold, myocardial contractility deteriorated, the stroke volume decreased, the general physical working capacity sharply fell. In compensated diabetes mellitus, versus decompensated one, subendocardial perfusion and myocardial contractility improved, stroke volume increased; the exercise tolerance threshold rose but did not reach normal.

Adult↗
PubMedDate not supplied

[The diagnosis of micro- and macroangiopathies of the lesser circulation in diabetic patients].

Patients with diabetes mellitus aged under 40 in the state of compensation demonstrate significant drop of pressure in the pulmonary artery system as compared to the corresponding parameter in those patients with diabetes mellitus beyond 40, which fact suggests presence of microangiopathies in the system of the pulmonary artery in the absence of concurrent pulmonary diseases and with similar duration of the illness.

Adolescent↗
PubMedDate not supplied

[The relationship of vascular changes and immune status disorders in patients with diabetes mellitus type 1].

Immunologic status was studied in 86 patients with type-I diabetes mellitus before and after treatment with decarise, thymaline and T-activin. With the aid of ECG, phonocardiogramme, apex cardiogramme, oscillogramme, there has been calculated index of vitality of the myocardium reflecting the subendocardial bloodflow. The principal parameters characterising bodily immune status (absolute number of T- and B-lymphocytes), T-suppressors counts as well as those of circulating immune complexes (CIC) were compared to the values for subendocardial bloodflow (end-diastolic pressure, index of vitality of the myocardium). There has been established strong inverse relation between the absolute numbers of T-, B-lymphocytes, and CIC, end-diastolic pressure and index of vitality of the myocardium, this being regarded as evidence in confirmation of the guarding role of the former and damaging one of the latter (CIC) under vascular pathology in diabetes mellitus.

Adjuvants, Immunologic↗