Biomedical subjects
Publications and source records attributed to S F Redo.
Long-term ventricular cerebrospinal fluid shunting can prove difficult in the neonatal population, particularly in those neonates who have had previous abdominal and vascular procedures. This article presents a technique of providing vascular access for ventriculoatrial shunting via the azygos vein for patients with limited vascular access and in whom ventriculoperitoneal shunting is not feasible.
A modification of the Baker jejunostomy catheter for use as an intestinal decompression tube for neonates is described. This has been used safely and effectively in the management of obstructive problems of the intestinal tract of diverse cause in full term and premature infants.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
A premature infant with severe respiratory distress developed the clinical and radiologic signs of pneumoperitoneum. At operation, free intraperitoneal air without visceral perforation was found. This case is unique in that pneumothorax was never observed and that interstitial emphysema or ischemic gastrointestinal lesions were not present at autopsy. The patient, however, was on a positive pressure ventilator for some time because of hyaline membrane disease and early pulmonary oxygen toxicity. Reduced parenchymal compliance could predispose to alveolar rupture. Although there was no clinical or anatomic evidence to point to a source of the intraperitoneal air, an undetectable pulmonary rupture with prompt dissection into the peritoneal cavity is the most likely explanation for the pneumoperitoneum.
Surgical procedures on patients with congenital disorders of blood coagulation can be performed with a high degree of confidence and an acceptable incidence of complications. During the period 1960-1975, 42 patients with congenital disorders of blood coagulation underwent 94 operative procedures at the New York Hopital-Cornell Medical Center. The coagulation defect was diagnosed preoperatively, in nearly all patients. Careful hematologic management, including specific factor replacement, is essential. The importance of meticulous hemostasis at surgery and careful monitoring of blood coagulation in the postoperative period is strongly emphasized.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Banding of the main pulmonary artery was undertaken in 11 litter-mate puppies and 8 young adult beagle dogs to study the response of the right ventricle to pressure loading. Five puppies and 3 young adult dogs acted as controls, undergoing sham surgical procedures without pulmonary artery banding. In one banded puppy and one banded young adult dog, adequate banding was not achieved and each was subsequently considered with its respective control group. A trans-band gradient of 15 mm Hg or greater was deemed a successful banding procedure. Banded puppies showed an increase in the trans-band pressure gradient in the year following surgery whereas young adult dogs showed a fall in the gradient, despite satisfactory banding as shown by cardiac catheterization 14 days after surgery. Cardiac muscle analyses indicated that the right ventricle of puppies responded to pulmonary banding by an increase in total organ weight, total tissue protein, DNA and RNA without altering the protein/DNA and RNA/DNA ratios. By contrast, young adult dogs showed only slight and insignificant increases in the protein/DNA and RNA/DNA ratios. Thus the response of the right ventricle to pulmonary artery banding in puppies is hyperplastic in nature, while in young adult animals the response to a similar stress load is with mild muscular hypertrophy and dilatation. This differential cellular response to the same stimulus based on the age of the organism is another demonstration of the principle that growth responses in the young involve cellular proliferation while those in the adult consist primarily of cell enlargement. It is, therefore, perhaps erroneous to refer to cardiac enlargement in newborns and infants as cardiac hypertrophy.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.