Malacoplakia causing bilateral ureteropelvic junction obstruction.
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Adult↗
Biomedical subjects
S Factor
Publications and source records attributed to S Factor.
Medical residents' education about occupational therapy: implications for referral.
OBJECTIVE: The purpose of this study was to assess sources of physician education concerning occupational therapy and to determine whether these sources influence occupational therapy referral rates. METHOD: One hundred fifteen medical residents from Thomas Jefferson University Hospital, Philadelphia, Pennsylvania, were surveyed. RESULTS: Residents learn about occupational therapy through informal, direct, and interactive types of contacts (touring occupational therapy departments, having personal contact with an occupational therapist, having a family member receive occupational therapy). Perceived knowledge about occupational therapy was not significantly associated with referral rate, but it did influence a resident's desire for further education about occupational therapy. CONCLUSION: Strategies for increasing medical residents' understanding of occupational therapy and for increasing their referrals to occupational therapy include opportunities for small group role playing, structural system changes within clinical sites, and direct marketing to consumers.
Adult↗
Escalating interferon-alpha-2b dose for patients with chronic hepatitis C.
BACKGROUND/AIMS: We examined the effectiveness of escalating the dose of interferon-alpha-2b in subjects with chronic hepatitis C who did not respond to usual treatment with 3,000,000 units 3 times a week. METHODOLOGY: Treatment was started with 3,000,000 units of interferon-alpha-2b 3 times a week. If serum alanine aminotransferase activity was not normal at 12 weeks, the dose was increased to 3,000,000 units daily. If serum alanine aminotransferase activity was not normal after 12 weeks, the dose was increased to 5,000,000 units daily. RESULTS: Fifty-one subjects started treatment. Twenty-nine subjects had their dose increased to 3,000,000 units daily and only 1 responded (3%, 95% confidence interval 0-10.9%) while 41% (95% confidence interval 21.4-60.6%) had to discontinue treatment at this dose because of adverse events or intolerance. Of 14 subjects who had their dose increased to 5,000,000 units daily, none (95% confidence interval 0-3.6%) responded, while 43% (95% confidence interval 13.5-72.5%) had to discontinue treatment. CONCLUSIONS: Escalating doses of interferon-alpha-2b are not effective and are associated with increased toxicity and intolerance in patients with chronic hepatitis who do not respond to initial treatment with 3,000,000 units 2 times a week.
Adult↗