PubMed Health⌕ Search

Biomedical subjects

S Fakhir

Publications and source records attributed to S Fakhir.

15 recordsLinked to original sources
PubMed1992

Prognostic factors influencing mortality in meningococcal meningitis.

The clinical features and some laboratory parameters of 247 cases of meningococcal meningitis admitted between January 1983 and April 1990 to a paediatric ward in Jawahar Lal Nehru Medical College Hospital, India were analyzed retrospectively. A total of 189 (76.5%) were more than 5 years of age. The maximum number of cases occurred between October and April each year. Complications included bleeding tendencies, neurological deficits, gangrene of limbs, arthritis, uveitis and cataract. The overall mortality rate was 16%. A scoring system based on some clinical characteristics correctly predicted a fatal outcome in all but three children.

Adolescent↗
PubMed1991

C-reactive protein in CNS infection.

Serum and CSF levels of CRP were measured by radial immunoassay in 99 subjects consisting of 20 controls, 34 pyogenic meningitis (PM), 21 tuberculous meningitis (TBM) and 24 viral encephalitis (VE). There was significant difference in the CRP levels (p less than 0.01) depending on the type of disease in both serum and CSF. The initial serum and CSF levels of CRP in patients with TBM was intermediate between those of PM and VE and were found to be significantly (p less than 0.001) low when compared with three days post treatment levels in children with PM. Both serum and CSF-CRP levels were significantly high (p less than 0.001) in patients succumbing to death than those who survived. Measurement of CRP in serum and CSF is a useful parameter in differentiating partially treated PM from TBM.

Biomarkers↗
PubMed1991

Celphos poisoning.

Explore the source record for details and available documents.

Aluminum Compounds↗
PubMed1990

Comparison of temperatures at different sites in term and pre-term neonates.

Temperatures of 30 term and 20 preterm neonates were recorded by mercury-in-glass thermometer at 4 measurement sites; rectum (2 cm beyond anus), external auditory canal, axilla and between skin and mattress. Whereas, the mean rectal and aural temperatures in term infants were significantly higher than their preterm counterparts (p less than 0.01), axillary and skin mattress temperatures did not differ significantly in the two groups. The variation between stabilized temperature at four measurement sites was less marked in preterm as compared to term infants. The skin mattress temperature measurement is a simpler technique and it closely approximates the rectal temperature in preterm infants. Temperatures at all the measurement sites stabilized by 5 minutes both in term and preterm infants.

Body Temperature↗
PubMed1989

Cell-mediated immune responses in malnourished host.

One hundred children in the age group 6 months to 5 years were investigated for cell-mediated immune response in relation to their nutrition. The nutritional status was assessed by the Wellcome classification. The majority (54 per cent) of children had marasmus. Absolute lymphocyte count was found to be significantly low (P less than 0.01) in all malnourished groups except in mild forms of undernutrition. Small lymphocytes were also found to be significantly decreased (P less than 0.001) in malnourished children. A significant depression (P less than 0.001) was observed in the percentage and absolute T cells in all the malnourished children with kwashiorkor who showed the maximum depression of counts. All the control children showed DNCB skin reactions above grade 2+ while only 39 per cent of malnourished children showed reaction of this grade. After 4-6 weeks of dietary therapy, T cell counts were comparable with control values and DNCB skin test returned to normal in more than 75 per cent of cases.

Child, Preschool↗
PubMed1989

Renal function in acute malaria in children.

Tests for renal function were performed in 75 smear positive children with acute malaria together with 10 control children. Plasmodium vivax and Plasmodium falciparum accounted for 52 and 46 per cent cases, respectively. Renal impairment in the form of decreased endogenous creatine clearance (less than 65 ml/min/m2) was noted in 36 of the 75 children with malaria. Plasmodium falciparum was responsible for 66 per cent and P. vivax accounted for 30 per cent cases of renal impairment. Plasmodium falciparum parasitaemia produced significantly greater reduction in endogenous creatine clearance (r = 0.198). Fourteen of 36 patients with decreased endogenous creatine clearance who attended for follow-up showed that their creatinine clearance had returned back to normal.

Acute Disease↗
PubMedDate not supplied

A comparative study of three types of ORS in the management of diarrheal dehydration.

Seventy five infants and children aged 6 months to 4 years admitted to Pediatrics services of J.N. Medical College, A.M.U., Aligarh with acute watery diarrhea with or without vomitings and associated with varying degree of dehydration were studied. They were randomly divided into three groups--(A, B, C) and were rehydrated with WHO standard ORS, super ORS and Rice water electrolytes solution. These children were subjected to investigations like hemogram, hematocrit, blood urea, blood glucose, plasma electrolytes, recorded on admission and repeated at 6 hours, 24 hours and at the time of discharge. The observation emerging out of this study include lower rate of purging, earlier control of vomitings, greater weight gain, earlier urination and consistently lower requirement of ORS and shorter time required for initial rehydration associated with early normally in laboratory parameters in dehydrated children receiving either super ORS or rice water electrolyte solution as compared to those on standard ORS. The difference in all these parameters was statistically significant.

Child, Preschool↗