PubMed Health⌕ Search

Biomedical subjects

S Farquhar

Publications and source records attributed to S Farquhar.

5 recordsLinked to original sources
PubMed1991

Enhancing the spelling performance of learning disabled students. Task variation does not increase the efficacy of directed rehearsal.

We investigated whether the efficacy of directed rehearsal could be enhanced by increasing a student's motivation through task variation. The efficacy of three conditions (directed rehearsal, directed rehearsal combined with task variation, and no-training control) on the spelling performance of four students with learning disabilities was compared in an alternating treatments design. Following each spelling error during the directed rehearsal condition, the teacher pronounced the word, the student pronounced the word, the teacher said aloud each letter of the word, and the student said aloud each letter of the word as he wrote the word correctly. This sequence was repeated five times. The same procedure was used during directed rehearsal plus task variation, except that previously learned words were alternately presented with new words. Results showed that although the two training conditions were more effective than no training, there was no difference between the two training procedures in terms of the cumulative number of words learned to criterion. This study showed that the addition of task variation to directed rehearsal does not increase the spelling proficiency of learning disabled students.

Adolescent↗
PubMed1987

Favorable effects of sulfasalazine on small bowel Crohn's disease: a long-term study.

Due to conflicting reports in the literature regarding the efficacy of sulfasalazine for Crohn's disease (CD) involving small bowel alone, we reviewed the treatment results of our systematic sulfasalazine treatment in CD over a 23-yr period. We identified 28 patients with CD of small bowel alone treated between 1 and 23 yr by means of sulfasalazine alone and who went into complete clinical remission. Of these, 12 also showed total regression of radiographic abnormalities, 12 showed partial regression, while four patients still await radiographic reexamination. While our data do not permit a precise estimate, it seems that about 25% of patients with small bowel CD respond to sulfasalazine alone. Reasons are discussed why our data are at variance with some and in accord with other reports. While our study of necessity could not be carried out in double-blind fashion, patients served as their own controls, having previously failed to respond to other treatment modalities or no treatment. We conclude that sulfasalazine should be tried in the treatment of CD of small bowel because of its relatively low toxicity and reasonably high efficacy.

Adolescent↗
PubMed1968

The osmotic behaviour of Sephadex and its effects on chromatography.

1. Sephadex in bead form shows reversible changes of inner volume when immersed in solutions of a non-penetrating solute. These changes are in accordance with the theory of Flory (1953) for the swelling of gels. This makes possible the use of single beads for measuring the osmotic pressures of polymer solutions, up to or beyond 1kg./cm.(2). 2. Measurements of the inner volume of Sephadex G-200 by equilibrium dilution, at various concentrations of dextran 500, gave values in agreement with those obtained from the dimensions of single beads. 3. Measurements by chromatography of the inner volume of Sephadex G-200 gave values that differed slightly but significantly from those obtained by the other methods. Similar small disagreements were found between the dilution and chromatographic values for bovine serum albumin measured in the presence of various concentrations of dextran 500. The major factor that affects the dependence of the chromatographic elution volume (of dextran 500) on concentration is shown to be the change of the inner volume of the Sephadex, with dynamic factors playing a minor role. 4. Contrary to the findings of Ackers (1964), the equilibrium dilution and chromatographic methods gave closely agreeing values for the distribution coefficient, K(av.), of bovine serum albumin on Sephadex G-200; this cast doubt on his explanation of the nature of chromatographic separations on Sephadex.

Animals↗