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Biomedical subjects

S Fassino

Publications and source records attributed to S Fassino.

At least 19 recordsLinked to original sources
PubMed1992

The image of self and of the environment in drug abusers: a comparative study using the TAT.

This study attempted to add to our understanding of the heroin abusers' identity problems, using images of the self and the environment. Murray's Thematic Apperception Test (TAT) was applied to a group of male drug users undergoing withdrawal treatment with methadone and also to a group of male, non-drug using controls. The needs of the subjects and the demands of the environment, plus interaction between the two, were compared between the two groups to obtain information about the self and lifestyle. Among the data which emerged, is an increased need for destructive aggression and an environment experienced as coercive and emarginating. Among the interactions we observed coerced imagination, difficulties in identification, personal relationships based on abandonment with persecutory projection of the female figure and a tendency toward immature defences such as avoidance, denial and acting out. This information is discussed in relation to possible means of treatment.

Adult↗
PubMed1982

[Effect of morphine on the exploratory behavior of mice].

The authors, after going carefully over the specific bibliography on the matter, report their results relating to exploratory behaviour in mice after administration of morphine (1 mg/kg i.p.). Exploratory behaviour was evaluated using an automatic recording hole-board, that simultaneously registered the locomotor activity. At the used doses, morphine did not produce variations either in exploratory behaviour or in locomotor activity of utilized mice, in comparison with drug-naive subjects. At the end, some possible interpretations are proposed about obtained results.

Animals↗
PubMed1982

[Effect of naloxone on the exploratory activity of mice].

The authors after going carefully over the specific bibliography on the matter, report their results relating to exploratory behaviour in mice after administration of naloxone (0, 05 mg/Kg i.p.). Exploratory behaviour was evaluated using an automatic recording hole-board, that simultaneously registered the locomotor activity. At the utilized doses, naloxone produced a significant decrease of exploring activity and a significant increase of motility, in comparison with drug-naive subjects. At the end, some possible interpretations are proposed about obtained results.

Animals↗
PubMed1982

[Effect of simultaneous administration of morphine and naloxone on the exploratory behavior of mice].

The authors, after going carefully over the specific bibliography on the matter, report their results relating to exploratory behaviour in mice after simultaneous administration with morphine (1 mg/kg i.p.) and naloxone (0,05 mg/kg i.p.). Exploratory behaviour was evaluated using an automatic recording hole-board, that simultaneously registered the locomotor activity. Morphine and naloxone simultaneously administered produced, at the used doses, a significant statistic decrease in exploratory behaviour, while locomotor activity was unchanged, in comparison with drug-naive subjects. At the end, some possible interpretations are proposed about obtained results.

Animals↗
PubMed1980

[Short-term memory. An experimental model].

In the present work we aimed to elaborate an experimental model to evaluate and quantify the short-term memory in experimental animals, in this case in mice. It seemed ideal to us the employment of a spontaneous behaviour, i.e. the re-exploration of the hole board, automatically recorded by animals which had previously explored at a 24 h interval. The data obtained show that, when re-exploring, the animals show a statistically significant decrease, compared to the previous exploration. It can be concluded that the animals had a mnestical retention and that it can be validly quantified. This shows the validity of this experimental model, in order to study the short-term memory in mice.

Animals↗
PubMed1980

[Inhibitory effect of scopolamine on recent memory of mice].

In this research the Authors have studied the action of scopolamine on the memorization of the explorative behavior of the mice. They gave scopolamine before each of the 2 explorations made at an interval of 24 h one from the other. The results obtained show that in these experimental conditions, scopolamine cancels the short-time memory in a more complete fashion compared to the only administration before the second exploration. The Authors advance the hypothesis that this effect of scopolamine can be in relationship to its action on the cholinergic system.

Animals↗
PubMed1979

[Effect of scopolamine on the memory of exploratory behavior in the mouse].

In the present work it has been evaluated the action of scopolamine on the extent of exploration in mice, whose exploring behaviour had been already earlier examined. Such behaviour has been evaluated using a hole-board. The goal has been to detect the influence of the substance on the short-term memory of mice. The method used has shown to be effective. By the exam of the results of this work it can be concluded that the scopolamine at a dose of 1 mg/kg has an evidence effect of short-time memory in mice by causing a hypomnesia.

Animals↗
PubMedDate not supplied

[Borderline pathology: follow-up study. Preliminary report].

The work is based on the frequent use of the term "borderline" in clinical practice, in spite of the fact that this word still tends to have a controversial and ambiguous meaning. Patients who were admitted to the Psychiatric Clinic at the University of Turin between 1974 and 1980 with diagnoses of borderline pathologies or marginal psychoneurosis were followed-up in the study. The subjects in question were reexamined after an interval of between 8 and 14 years (the majority between 10-12 years). An attempt was made to compare the two diagnoses using DSM III R criteria. Family status and employment were also taken into account. It was observed that the diagnosis of marginal syndromes recorded in the patient's clinical records did not correspond to the DSM III R borderline diagnosis, and rather than referring to a precise syndrome it reflected an area of diagnostic uncertainty. This raises various questions both with regard to the role of psychiatry, and in relation to the incidence of cultural factors in influencing observations.

Adolescent↗
PubMedDate not supplied

[Discussion groups with chronic psychotics in the context of community therapy].

The paper describes the Authors clinical experience of "discussion groups" with psychotic patients. Attention is focused on the problems arising from the community therapy context, the general layout of the setting, the definition of objectives and methods, and in particular the attitude of group leaders.

Chronic Disease↗
PubMedDate not supplied

[Intellectual efficiency and drug addiction].

The intellectual efficiency of a group of drug addicts and a group of neurotic and senile subjects was tested against the Wechsler-Bellevue Intelligence Scale. Alongside an anxiety-related reduction in the efficiency of certain functions and a reduction in the ability to concentrate, the addicts evidenced a reduction in efficiency in the organisation of tasks and prediction of results related to depression of disharmony in the interaction of the various functions.

Adolescent↗
PubMedDate not supplied

Non-associative learning in the mouse. Effect of morphine and naloxone.

The study evaluates the effect of morphine and naloxone on the process of non-associative learning in the mouse. Exploratory behavior was measured in thirty-six male albino mice (Suisse) placed on a Boissier and Simon hole-board, the procedure being repeated 24 h later after administration of naloxone and/or morphine, or bidistilled water i.p. The results show that the inhibitory effect naloxone has on the recollection process of the mnemonic traces appears to be masked by morphine.

Animals↗