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Biomedical subjects

S Feffer

Publications and source records attributed to S Feffer.

4 recordsLinked to original sources

Hereditary warfarin resistance.

We report on a case of hereditary warfarin resistance in a 27-year-old black man. Hereditary warfarin resistance is a rare disorder transmitted as autosomal dominant. It should be suspected in patients who require high doses of warfarin, achieve high plasma warfarin levels, and have a normal plasma warfarin clearance. Treatment includes either high dose warfarin or heparin (subcutaneous).

Adult↗

Thymic hyperplasia following successful chemotherapy. A report of two cases and review of the literature.

True thymic hyperplasia is rare in adults. The authors have encountered this entity in two patients who were deemed disease-free following combination chemotherapy for malignant disease. It cannot be assumed that the development of a mediastinal mass or its persistence following chemotherapy is due to recurrent or residual disease. The interrelationship between the immunosuppressive effects of neoplasia and chemotherapy with the resultant thymic overgrowth remains to be clarified.

Adult↗