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Biomedical subjects

S Ferková

Publications and source records attributed to S Ferková.

7 recordsLinked to original sources

[Pars plana vitrectomy for diabetic pseudophakic macular edema].

PURPOSE: In retrospective study to evaluate the anatomical and functional results of pars plana vitrectomy (PPV) with peeling of the inner limiting membrane (ILM) on pseudophakic eyes with diabetic macular edema. MATERIAL AND METHOD: PPV with peeling of the ILM was performed in 5 eyes (5 diabetic patients) after cataract surgery with posterior chamber intraocular lens implantation. Group of patients enrolled 4 female and one male aged from 44 to 62 years (average 56.2 y.). 2 eyes had undergone focal fotocoagulation previously for clinically significant macular edema. The macular edema was diagnosed by clinical examination and by retinal fluorescein angiography from 3 to 8 months (mean 6 m.) after cataract surgery. Visual acuity (VA) and angiographic changes were monitoring. RESULTS: In pseudophakic eyes with diabetic macular edema that underwent surgery, the angiography documented decrease of hyperfluorescens in all cases. VA improved in 3 eyes (80%) more than +2 lines of Snellen test, stabilized in one eye (20%). VA detoriated in one eye by -1 line of Snellen test. CONCLUSION: Our results demonstrated that PPV with ILM peeling is effective surgical procedure on pseudophakic diabetic macular edema.

Adult↗

[The therapy for acute acquired syphilitic uveitis].

PURPOSE: In retrospective study (analysis) to report the effectiveness of therapy on anatomic and functional outcomes in patients with acute acquired syphilitic uveitis. DESIGN: Retrospective case-control study. PARTICIPANTS: 3 patients (4 eyes) with symptoms of ocular acute inflammation which occurred in latent stage of syphilis are included in our study. In all patients uveitis was the first clinical symptom of syphilis. METHODS: In all 3 patients the infection of acquired syphilis was diagnosed using specific and non-specific tests for treponemal antibody. In 2 eyes we performed diagnostic and therapeutic pars plana vitrectomy. The management of ocular syphilis in all patients consisted of mega units of aqueous penicillin intravenously or intramusculary, in 2 patients we used the combination with steroids. RESULTS: In 2 eyes with perioperatively obtained material of vitreous (during pars plana vitrectomy) specific treponemal antibody was detected using specific (TPHA) test. In the third patient infection was verified serologically. The final visual acuity of all 4 eyes is better than or equal to 6/12. The visual acuity of one exe is 6/6. CONCLUSION: Uveitis and neuroretinitis may be the first symptom of acquired syphilis in latent stage. Early antibiotic treatment significantly improves anatomical reparation of infection and visual outcomes.

Acute Disease↗

[Initial experience with the EAS-1000 (NIDEK) anterior segment analyzer].

The analyzer of anterior segment EAS-1000 is one of recently developed diagnostic devices, used for digital photography for the analysis and storage of data about the anterior segment of the eye. The aim of the contribution is to inform the public about possible use of the apparatus in clinical and field practice.

Anterior Eye Segment↗

[Antimetabolites in glaucoma surgery--long-term results].

PURPOSE: To observe the long term success of antimetabolites used in glaucoma filtering surgery in eyes with high risc of failure. MATERIAL AND METHOD: Two groups of patients undergone trabeculectomy with the use of antimetabolites 5-Fluorouracil (5-FU) and Mitomycin C (MMC) are included in this retrospective study. 5-FU was administered postoperatively 1-10 times in the dose of 5 mg/ml in subconjunctival injection on 32 eyes. Follow up time ranged from 8 months to 9 years. Mitomycin C was administered intraoperatively in the dose of 0.2 mg/ml, on subconjunctival sponge with application time from 3 to 5 minutes on 15 eyes. Follow up time ranged from 7 month to 4.5 years. RESULTS: Intraocular pressure (IOP) before operation with the use of 5-FU was in average 28.8 mmHg (22-50 mmHg) at the end of therapy with 5-FU was 17.6 mmHg (10-30 mmHg) and in the last examination was on average 19.5 mmHg (14-28 mmHg). IOP before operation with the use of MMC was in average 30.3 mmHg (22-40 mmHg), the seventh day after administration of MMC 12.7 mmHg (6-20 mmHg) and in the last examination was in average 18 mmHg (9-28 mmHg). During the long term observation of IOP values in the 5-FU group there was 79.2% success and in the MMC group there was 83.3% success (IOP up to 20 mmHg with or without therapy). Decrease of IOP was statistically significant. CONCLUSION: Antimetabolites improve the success of filtering surgery in high risc glaucomas. The long term follow up shows that failure of filtration in these types of glaucomas is still a serious clinical problem.

Adult↗

[Endophthalmitis after lens surgery].

At the University Eye Clinic Bratislava we performed a retrospective study on the occurrence of endophthalmitis after lens operations. Over the years 1993-1995 we performed 2374 lens operations. Endophthalmitis occurred in 20 eyes (0.84%). Endophthalmitis occurred after uncomplicated as well as after surgical procedures with various perioperative complications. All patients were treated with antibiotics locally and parenterally. Nine patients were treated with steroids. In these patients we did not performed pars plana vitrectomy. Owing to endophthalmitis one eye was eviscerated. In one eye after previous vitrectomy for proliferative diabetic retinopathy developed later inoperable retinal detachment. In one eye was present an old retinal detachment before the cosmetic cataract extraction was performed. Without any complications were cured nine eyes. In eight eyes are remained iris synechiae and vitreous opacities. Two eyes lost light perception and one eye was without light perception already before cataract extraction. The final visual acuity was better than 2/60 in 70% of the eyes and better than 6/36 in 50% of the eyes.

Cataract Extraction↗

[Endophthalmitis after intraocular interventions].

BACKGROUND: Endophthalmitis is serious complication of intraocular surgery. At the University Eye Clinic Bratislava we performed a retrospective study on the occurrence of endophthalmitis after various intraocular procedures. MATERIAL AND METHODS: Over the years 1993-1995 we performed 2374 cataract extractions, 305 anti-glaucoma operations, 106 perforating keratoplasties and 926 pars plana vitrectomies. The charts of all patients were reviewed. The occurrence of endophthalmitis, type of surgery, perioperative complications, elapsed time between surgery and start of endophthalmitis, results of preoperative conjunctival smear cultures, final anatomical and functional results were evaluated. RESULTS: The frequency of endophthalmitis after cataract extraction was 0.84%, after antiglaucoma surgery 1.31% and 0.97% after pars plana vitrectomy. No endophthalmitis was found after penetrating keratoplasties. In most cases endophthalmitis began in the first three days after surgery. Endophthalmitis occurred after uncomplicated as well as after surgical procedures with various perioperative complications. The preoperative conjunctival smear cultures were sterile in 22 patients. Staphylococcus epidermidis was the most commonly cultured germ. All patients were treated with antibiotics parenterally and locally. Pars plana vitrectomy and intravitreal application of antibiotics was performed only exceptionally. Enucleation was required in two eyes and two other eyes become phthitical. 22 eyes recovered without serious complications. Five eyes were blind and in 11 eyes the final visual acuity was better than 6/36. CONCLUSIONS: Pre-, peri-, and postoperative measures must be improved to prevent postoperative endophthalmitis. In cases of endophthalmitis all therapeutical options have to be performed as soon as possible to save the patient's eye and sight.

Adult↗