Biomedical subjects
S Ferrer
Publications and source records attributed to S Ferrer.
[Bulimia, a form of pathological eating. Clinical and electroencephalographic experience in 16 patients].
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[Determination of plasma prolactin in patients with breast dysplasia].
Prolactin is determined by means of radioimmunoassay in the postovulatory phase of a group of women with mammary dysplasia. A specially increased concentration of prolactin is found in the proliferative dysplasias (multiple intraductal papillomatosis and invasive sclerosing adenosis), that may be considered as preneoplastic processes.
[Syndromic diversities in Creutzfeldt-Jakob disease: neurophysiological and histopathological correlates].
Two syndromatic forms of Creutzfeldt-Jakob disease are illustrated with data from two cases confirmed by necropsy and studied by means of electroencephalogram, evoked potential recording and neuropathological techniques. One of the cases presented the typical hypersynchronous periodic discharges through to be characteristic of this disease. The other did not exhibit epileptiform discharges, showing an evolution in which progressive diffuse slowing was the prominent feature. Cortical spongyosis, gliosis, and neuronal lose were intense in the case showing spikes, and moderate in the one without spikes. Subcortical involvement was similar in both cases. This different topography of pathological involvement might explain, in addition to electroencephalographic findings, the different behavior of somatosensory evoked potentials, which were of larger amplitude in the case showing epileptiform discharges, although in both cases deterioration of clinical state was accompanied by a progressive amplitude decrement in the evoked potential. Sleep induced by barbiturates was disrupted in the case with spikes, its pattern being closer to normal in the case with less severe cortical involvement. A Wada test demonstrated that discharges in the hemispheres were independent. Spike periodicity is discussed. It is postulated that the heavier involvement of cortical layers II to IV deprive the remaining pyramidal cells of inhibitory influences, a condition which might explain the generation of periodic spike discharges.
Subacute spongiform encephalopathy (Creutzfeldt-Jakob disease) associated with normal-pressure hydrocephalus Anatomoclinical report of one case.
The occurrence of two different dementing diseases, Creutzfeldt-Jakob disease and normal-pressure hydrocephalus in a single patient is described. The inefficacy of a shunt procedure in this particular case, and the need of a brain biopsy in patients with normal-pressure hydrocephalus before undergoing cerebrospinal fluid shunting are stressed. A purely coincidental occurrence, or a possible aetiopathogenic relationship between both diseases are postulated.
Three new species of penicillium.
Three new species of microfungi belonging to the genus Penicillium Link ex Fries are described and illustrated. All but one have been isolated from the atmosphere of las Palmas, capital city of the island of Gran Canaria (Canary Islands, Spain). They clearly differ from all species of the genus described so far and are, therefore, described and proposed as new species: Penicillium hispanicum sp. nov., Penicillium grancanariae sp. nov., and Penicillium palmensis sp. nov.
[Regional curare test in the evaluation of myasthenia gravis (author's transl)].
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[Treatment of multiple sclerosis (author's transl)].
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[Genetic aspects of muscular dystrophy (author's transl)].
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[Total thymectomy in the treatment of myasthenia gravis: clinical results in 24 patients (author's transl)].
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[Clinical and therapeutic aspects of brain edema (author's transl)].
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[Acute myolisis: a clinical-pathological report (author's transl)].
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[Cerebral hypoxia].
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[Hypertensive cerebral hemorrhage. Anatomo-clinical analysis].
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[Congenital muscle disorders].
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[Pneumoencephalographic and clinical study of permanent neurological complications in chronic alcoholics].
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[Dysglobulinemic polyneuropathies].
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[Lupoid polyneuropathy. Clinical case].
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