Biomedical subjects

S Forrest

Publications and source records attributed to S Forrest.

22 records · Page 2Linked to original sources

PubMed1979

Sensorimotor rhythm feedback training and epilepsy: some methodological and conceptual issues.

This study examined the hypothesis that the enhancement of a 12-16 Hz sensorimotor rhythm in the EEG is inhibitory to epileptic seizure activity. The effects of training to enhance 12-16 Hz central EEG, to enhance 8-10 Hz central EEG, to suppress high voltage EEG activity, and of random feedback were compared over a period of 12 months in three adult patients suffering from chronic, drug-refractory epilepsy. All three patients experienced a significant reduction in seizure rate by the end of the study, but this was not related to any one particular training condition. It is suggested that the therapeutic mechanism might involve placebo effects, relaxation training, or a facilitation of EEG desynchronization, the effect being idiosyncratic to the individual patient.

Adult↗

PubMedDate not supplied

Contracting in the NHS quasi-market.

This paper examines the development of contracting within the NHS on the basis of the data collected as part of a national survey of English District Health Authorities carried out in late 1994. The paper starts with a discussion of the background to contracting and its evolution during the first 4 years of the NHS internal market. The second section describes the methodology employed in the national survey. The third section presents the results of the survey alongside a discussion of their relevance in terms of the economics of contracting. This section shows the prevalence of different types of contracts and discusses the emergence of the most common type-sophisticated block contracts. Details are provided of how contracts deal with issues such as the measurement of activity, the pricing of projected activity and of activity variances (mainly at marginal cost), as well as the involvement of clinicians in contracting. Other topics explored include the management of extra contractual referrals, contracting for specialized services, arbitration arrangements, the purchaser efficiency index and contracts with the independent sector. The final section offers some concluding thoughts on the current state and future of contracting in the NHS.

Contract Services↗

PubMedDate not supplied

Molecular analysis of human muscular dystrophies.

The ability to map disease loci using restriction fragment length polymorphisms (RFLPs) identified by DNA probes has revolutionized molecular genetics. Duchenne and Becker muscular dystrophies have been shown to be localized within the same very small region of Xp21 on the human X chromosome. The mutation itself should soon be identified at the DNA level, which will permit a detailed analysis of the molecular defect at the biochemical level. Rapid progress has also been made in the study of myotonic dystrophy on chromosome 19. DNA markers closely linked to the mutant locus have been identified, making antenatal diagnosis possible in informative families. Autosomal recessive muscular dystrophies are more difficult to study, but the means to localize even these mutations is being developed. The next decade should prove to be an exciting one for those involved in the molecular analysis and clinical management of human muscular dystrophies.

Chromosome Mapping↗

PubMedDate not supplied

Toward understanding the self.

Others may know "me" but only "I" am the knower of myself. The metaparadigm of nursing includes four concepts: health, environment, nurse, and person. Each concept is complex and can be interpreted in diverse ways. The concept analysis in this article focuses on one aspect of person, specifically "self:" its birth, development, and loss. The author makes suggestions for using the analysis in nursing education, theory development, and clinical practice in caring for and promoting the health of individuals, groups, and families.

Adolescent↗