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S Fouere

Publications and source records attributed to S Fouere.

3 recordsLinked to original sources
PubMed2002

Anaphylactic shock secondary to intravenous administration of folinic acid: a first report.

BACKGROUND: Folates, components of the B-complex vitamins, have numerous pharmacological effects. In oncology combining folates with 5-fluorouracil (5-FU) enhances the cytotoxic effects of chemotherapy in colon cancer patients. Folic acid has been rarely involved in adverse allergic reactions. To the best of our knowledge no anaphylactic reaction secondary to folinic acid (FA) administration has ever been reported before. PATIENTS AND METHODS: An 80-year-old patient had adjuvant chemotherapy for colon cancer including FA and 5-FU and irinotecan as a second line agent after multiple metastases. RESULTS: Following FA administration anaphylactic shock occurred. Diagnosis was made according to the French method of adverse reactions monitoring. CONCLUSION: Anaphylactic shock may be an adverse reaction of FA in patients receiving chemotherapy for colon cancer.

Aged↗
PubMedDate not supplied

[Herpetiform ulceration: 5 cases].

BACKGROUND: Mouth ulcers are frequently observed, mostly caused by trauma and aphthae. We report five cases of herpetiform ulceration, a rare clinical form of aphthae often mistaken for herpetic stomatitis because of the similar clinical presentation. CASE REPORTS: All patients were men with late age at onset (44.8 years). All had numerous tiny very painful ulcers covering all parts of the oral cavity. Consequences were sometimes severe (weight loss and general weakness in two patients, requiring hospitalization in one). Diverse clinical courses were observed (from no recurrence to monthly recurrence). Systemic steroids resulted in dramatic improvement in two patients, colchicine prevented recurrences in three of them. DISCUSSION: These observations illustrate well this rare disease: herpetiform ulceration. We found oral corticosteroids provide effective cure and observed the preventive action of colchicine. Both findings should be confirmed in larger series.

Adult↗