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Biomedical subjects

S G Burkov

Publications and source records attributed to S G Burkov.

At least 19 recordsLinked to original sources
PubMed2005

[Oral cavity manifestations of gastroesophageal reflux disease].

The aim of the study was to investigate changes in the oral cavity and the gastroesophageal zone of the patients receiving rabeprazol, a proton pump inhibitor (PPI). The subjects were 88 patients with gastroesophageal reflux disease (GERD), who had changes in the oral cavity typical of this disease. The patients were divided into four groups. Group I included patients with non-erosive reflux disease; the other three groups were formed according to the degree of the severity of reflux esophagitis in accordance with Los Angeles classification of GERD: A, B, and C. The patients were administered rabeprazol as a PPI. The study found that oral cavity changes are associated with the degree of the gastroesophageal reflux. The study demonstrated high efficacy of rabeprazol in GERD patients with oral cavity changes.

2-Pyridinylmethylsulfinylbenzimidazoles↗
PubMed2002

[Interrelations of hyperplasia of gastric mucosa and helicobacter infection (based on data from a polyclinic center].

AIM: To examine a relationship of hyperplastic processes in the gastric mucosa (GM) to Helicobacter infections. MATERIAL AND METHODS: A hundred patients aged 44 to 86 years who had gastric polyps [Group 1, foveolar hyperplasia (n = 21); Group 2, hyperplasiogenic polyps (n = 65), Group 3, adenomas (n = 14)] underwent esophagogastroduodenoscopy with biopsy of the mucosa from the athrum, body, and fundus of the stomach to reveal Helicobacter pylori (Hp) and GM morphological changes. RESULTS: Hp-associated chronic gastritis was detected in 56% of the patients (66.7, 52.3, and 57.1% in Groups 1, 2, and 3, respectively). The rate of Hp seeding correlated with the magnitude of inflammatory and dystrophic changes. As the regulation of epithelial growth and differentiation impairs, the magnitude of GM structural alterations increase. CONCLUSION: The findings indicate that there may be a relationship between the frequency, degree of Hp infection and the pattern of GM morphological changes, which makes it expedient to use eradication therapy in this group of patients.

Adenomatous Polyps↗
PubMed2002

[Hyperplastic processes of the gastric mucosa in helicobacter infections].

The investigation of possible H.p. role in the development of stomach mucous changes, promoting to arising of hyperplasiogenic polypus is the purpose of this study. Gastro-duodenal endoscopy with biopsy of stomach mucous from the antral part, body and bottom for H.p. diagnosis and morphological changes was made in 85 patients (at the age of 43-82 years) with hyperplasmiogenic polypus. The H.p. associated chronic gastritis was determined in 47.6% of the patients. H.p. intensity (prevailed weak and moderate--69.2%) correlated with the inflammation activity degree (1st and 2nd--80.3%) and with dystrophic changes (initial and moderate mucous atrophy--74.4%). The obtained data indicate the possible relation to H.p. infection frequency, degree and character of stomach mucous morphological changes. It allows to examine the expedience of the eradiction therapy for the patients with hyperplasiogenic polypus, infected by helicobacterial infection.

Adult↗
PubMed2002

[A case of the successful treatment of the esophageal leukoplakia with rabeprazole].

This clinical endoscopic study is of interest because clinical and endoscopic remission of the disease with a torpid course was achieved in a patient with gastroesophageal reflux disease with a continuously recurrent course complicated with leukoplakia under the condition of regular combination of preparations of the base course PPIs (Pariet) + prokinetic agent (Motilium) + antacid (Magalphil), conduction of continuous treatment during 12 weeks and subsequent supporting therapy (Pariet, 20 mg) during 6 months in the weekend treatment mode, as well as adherence to recommendations for changing the lifestyle.

2-Pyridinylmethylsulfinylbenzimidazoles↗
PubMed1999

[The efficacy of flonivin BS in the treatment of intestinal dysbacteriosis].

The paper presents results of intestinal dysbacteriosis (ID) treatment with flonivin in 25 patients. The diagnosis was made clinically and bacteriologically (fecal examinations). Flonivin BS proved to be an effective biological preparation for management of ID stage I and II. It is composed of bacteria which do not conflict with macroorganism, contribute to normalisation of intestinal biocenosis, is especially beneficial in ID induced by long-term administration of antibiotics.

Adolescent↗
PubMed1988

[Diseases of the upper digestive system in pregnant women].

The authors' and literature results concerning the peculiarities of a clinical course, diagnosis and therapy of the upper digestive tract in women during pregnancy were summed up. Exacerbation or first symptoms of diseases like cardiospasm, reflux esophagitis can often occur during pregnancy. Peptic ulcer in most pregnant women has a favorable course, exacerbations are rare. A conclusion has been made that measures aimed at the prevention of exacerbations and complications of these diseases, are recommended to women with chronic diseases of the digestive tract during pregnancy.

Digestive System Diseases↗