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Biomedical subjects

S G Gribakin

Publications and source records attributed to S G Gribakin.

13 recordsLinked to original sources
PubMed1985

Immunological protection of the neonatal gastrointestinal tract: the importance of breast feeding.

Immunoglobulins A, M and G were measured in the milk of 20 nursing mothers at the beginning of lactation and simultaneously in the faeces of their children. The IgA level in the human milk was very high especially during the first week of lactation. After the start of breast-feeding IgA rapidly increased in the faeces, whereas IgG and IgM concentrations were consistently very low. In 74 normal full-term bottle-fed infants IgA appeared in the faeces at the age of 3-4 weeks but the level was significantly lower than the IgA level in breast-fed infants at the same age. Secretory IgA of human milk is stable and resistant to gastrointestinal juices and enzymes, thus giving passive immunological protection to the digestive tract of the newborn infant.

Bottle Feeding↗
PubMedDate not supplied

[The carbohydrate composition of human milk].

The carbohydrate content of breast milk was investigated by capillary gas liquid chromatography. The milk samples obtained from 16 normal lactating mothers contained glucose, galactose, lactose, and 3-fucosidolactose. The content of monosaccharides in breast milk was 2-12 times higher than that in cow's milk. The lactose content amounted to 84-95%, whereas the ratio of alpha- tox beta-froms was within 0.92-0.95%. Breast milk was found to contain alpha- and beta-forms of 2- and 3-fucosidolactose which do not occur in cow's milk. The content of these forms accounted for 3%. The biological role of breast milk carbohydrates is discussed.

Adult↗
PubMedDate not supplied

[Natural feeding and its importance in forming local immunological protection in the gastrointestinal tract during the neonatal period].

The immune proteins content in the breast milk at the 1st week of lactation as contrasted to the data obtained by investigating immunoglobulins in feces of newborns breast-fed was studied. Both in the breast milk and in feces the A-class immunoglobulins being of great importance in the immunological protection of the mucosae prevail. A high level of immune proteins resistant to proteolytic enzymes ensures the state of local passive immunity in neonates receiving breast milk.

Adult↗