Biomedical subjects
Publications and source records attributed to S G Kocsis.
Besides the hypotelorism the mildest form of holoprosencephaly is the solitary incisor. In the case described, the girl had only high palate and torus palatinus, but no other alteration in the midline. One of her brothers had cleft lip and palate, which indicates genetical determination. The girl has been orthodontically treated.
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The adverse effects of ingested fluoride were investigated. The bone-age of children consuming drinking water containing optimum (about 1 mg/l) fluoride concentration with regard to caries prophylaxis was compared with the bone-age of those consuming drinking water containing low (0.14-0.26 mg/l) fluoride concentration. The examinations were conducted on 7-14-year old Hungarian children. The bone-age was determined by the TW2 method. No significant difference was found between the bone-age of the children belonging to the group consuming water with optimum fluoride concentration and those in the other group consuming water with low fluoride concentration.
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