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Biomedical subjects

S G Kurdiumov

Publications and source records attributed to S G Kurdiumov.

6 recordsLinked to original sources

[Gapkol--a new osteoplastic material].

Hapcol, a new osteoplastic material, representing a biological composition on the basis of a natural biopolymer collagen with biologically compatible osteotropic mineral hydroxyapatite has been developed and allowed for clinical use. It is intended for use in dentistry in surgical treatment of periodontal diseases, deformations of the abutment tissues of the face, filling of bone defects after cystectomy, surgery for bone plasty, etc. Hapcol is characterized by antiinflammatory action, stimulates repair osteogenesis and collagenogenesis. Joint stock company Polistom starts commercial manufacture of the new material.

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[Effects of the composition of bone tissue growth factors on cell growth on the model of long term culture of the bone marrow].

The experimental study of the properties of the collagen- and hydroxyapatite-containing osteoplastic material HAPKOL-I by bone marrow hemopoiesis was made in comparison with existing material HAPKOL. HAPKOL-I is a working name of the material consisting of HAPKOL and composition of non-collagen bone proteins produced from xenogenic bone material. Long-term cultures of bone marrow from mice (C57B1/6xCBA)F1 of dexter type were used. Cultivation time was 7, 14, 21 and 28 days. Intensity of hemopoietic processes was assessed on the samples; absolute count of stromal and hemopoietic cells on the membrane was calculated. It was found that in long-term cultures of the bone marrow stromal and hemopoietic cells develop on the materials HAPKOL and HAPKOL-I, processes of formation of hemopoietic microenvironment provide normal hemopoiesis. On both materials there was a gradual increase of cell counts, a rise in the number of stromal and a fall in the number of hemopoietic cells. More intensive hemopoiesis on the material containing non-collagen bone proteins may be due to this factor.

Animals↗