Therapeutic vs. prophylactic epidural blood patch.
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Comment↗
Biomedical subjects
S Gültekin
Publications and source records attributed to S Gültekin.
Repairing great duodenal defects in rabbits by ePTFE patch.
The aim of this experimental study was to evaluate the results of repairing large duodenal defects in rabbits by an ePTFE (Gore-Tex) soft tissue patch graft. A defect as large as 50% of the total circumference of the duodenum (i.e. Grade 3 injury) on anterior surface of the second part in 14 white New Zealand rabbits was done and repaired by 1 mm ePTFE graft. The stomach and duodenum were inspected for evidence of either leak or obstruction, and completeness of the mucosa covering the defect. Neither leak nor obstruction were observed and the whole grafted area was covered by the mucosa at the end of the sixth month. The main conclusion is that the method we used, is easy and reliable. Further experience will appropriate animal models is needed before this technique can be considered for application (in human duodenal injuries).
Animals↗
The effect of different anaesthetic agents in hearing loss following spinal anaesthesia.
The cause of hearing loss after spinal anaesthesia is unknown. Up until now, the only factor studied has been the effect of the diameter of the spinal needle on post-operative sensorineural hearing loss. The aim of this study was to describe this hearing loss and to investigate other factors influencing the degree of hearing loss. Two groups of 22 similar patients were studied: one group received 6 mL prilocaine 2%; and the other received 3 mL bupivacaine 0.5%. Patients given prilocaine were more likely to develop hearing loss (10 out of 22) than those given bupivacaine (4 out of 22) (P < 0.05). The average hearing loss for speech frequencies was about 10 dB after prilocaine and 15 dB after bupivacaine. None of the patients complained of subjective hearing loss. Long-term follow-up of the patients was not possible.
Adult↗