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Biomedical subjects

S Gabrovski

Publications and source records attributed to S Gabrovski.

10 recordsLinked to original sources
PubMed1999

[Lipoma of the temporal lobe].

This is a case report on a 16-year-old girl presenting lipoma located in the temporal cerebral lobe, in conjunction with an ever increasing frequency of epileptic seizures, unresponsive to the anticonvulsive treatment carried out. A comprehensive analysis is done of the data concerning clinical course, diagnostic examinations' specificity and microsurgical removal of the lipoma with ensuing optimal postoperative results--total abatement of epileptic seizures against the background of reduced anticonvulsive therapy throughout the 3.5 years observation period. The literature survey shows that intracranial lipomas with the location described represent as casuistic rarity.

Adolescent↗
PubMed1999

[The microsurgery of colloid cysts of the third ventricle].

Colloid cysts are rarely met with intraventricular pathology (0.2 to 2% of all intracranial tumors) with predilection development in the anterosuperior sections of the third ventricle. They occur in all age groups, but most frequently in the 3rd to 5th decade of life, and are characterized by running a nonspecific clinical course with chronic complaints of many years. They are considered as insidious conditions, since 10 to 30 per cent of cases may have an acute onset with fatal outcome within a few hours. This is a report on experience had with microsurgical approach to twelve patients presenting colloid cysts (7 women and 5 men aged 21 to 58 years). The clinical picture, early symptoms and clinical course in the series being examined are analyzed. Seven patients are operated by fronto-transcortical, and five--through anterior transcallosal access. In all instances total removal of the cyst and its content is achieved. No lethal outcome in the early and late postoperative period is recorded. Postoperative complications and the results of long-term follow-up study are comprehensively analyzed. There is no clinical evidence of relapses.

Adult↗
PubMed1999

[Intracranial hemorrhages in patients being treatment with anticoagulants].

Over the period 1994-1998, five patients presenting coagulation status impairment in the course of sintrom treatment are hospitalized in the Clinic of Emergency Neurology and Neurosurgery. Three of them are with craniocerebral trauma (2 severe forms--score 5 by the Glasgow Coma Rating scale, and one mild form--score 15), one has spontaneous intracerebral hematoma, and one--acute hydrocephalus against the background of ruptured aneurysm of the basilar artery (score 4). Three patients are given sintrom treatment because of rheumatic heart disease (2 with mitral valve prosthetic replacement and one in the post-commissurotomy period), and two--because of absolute arrhythmia, complicated by systemic emboli in the extremities and/or pulmonary artery. Four patients are subjected to operation--2 with craniocerebral injury, one with intracerebral hematoma and one with acute hydrocephalus of which in two cases the outcome is fatal. One female patient presenting serious craniocerebral trauma is not operated (refusal by the relatives) and dies. The therapeutic approach to this contingent of patients is comprehensively discussed.

Acenocoumarol↗
PubMed1998

[Clinical studies of patients with spinal cord metastases].

Eighty-one patients with spinal-cord tumors are hospitalized in the Clinic of Emergency Neurology and Neurosurgery over the period 1988 through 1997. Of the total number, 74 patients of which 25 presenting metastases from neoplasms with primary location out of the central nervous system, are subjected to operation. There are 4 tumors involving the cervical segment, 1--cervicothoracic, 17--thoracic, 1--thoracolumbar, and 2--lumbar segment. Histological verification is done in all patients operated on. The indications for undertaking surgery in this particular contingent of patients are discussed.

Contrast Media↗
PubMed1998

[A one-stage combined approach to tumors in the anterobasal portions of the third ventricle].

Regardless of the current progress in microneurosurgery, the operative management of tumors in the third ventricle is associated with a number of difficulties, and poses a serious challenge to surgeons. A numerous group of neoplasms with the aforementioned location are characterized by developmental course with secondary involvement of the III ventricle. Usually, it is a matter of tumors with suprasellar evolution (craniopharyngiomas, hypophyseal adenomas etc), penetrating through lamina terminalis and growing within the cavity of the ventricle. Radical removal of some of these tumors requires a many-staged approach--basal and transventricular--undertaken at different periods of time. The analysis covers five patients presenting tumors of the III ventricle--4 craniopharyngiomas and 1 dermoid cyst--where single stage basal (across lamina terminalis) and direct (transcallosal or across the lateral ventricle) access to the third ventricle is gained. The situations where such an approach is practicable, the peculiarities of the surgical technique, and the treatment results are discussed.

Adolescent↗
PubMed1997

[Central neurocytoma--the need for reassessment of histological diagnoses in tumors in the lateral and third ventricles].

J. Hassoun and co-workers (1982) described two cases presenting intraventricular tumors of nervous origin, coined by them with the term "central neurocytoma" of the ground of electron microscopic data. As shown by the studies of other authors, central neurocytoma represents a separate morphological entity having light- and electron-microscopic and immunohistochemical characteristic of its own. In the recently published WHO classification of brain tumors (1993) central neurocytoma is entered as a tumor presenting new morphological patterns. Central neurocytoma occurs mainly in young persons, develops in the lateral and third ventricle, comparatively well differentiated from surrounding structures, rich in calcifications, disclosing proper relative specificity during CT scanning and MRI study. Light-microscopically this tumor bears resemblance to, and is erroneously diagnosed as oligodendroglioma or ependymoma. Proceeding from retrospective reassessment of two patients with intraventricular tumors and an additional observation, and on the ground of pertinent literature data, the morphological, clinical and nerve imaging characterization of central neurocytoma is outlined--a tumor met with in the daily routine practice, but usually erroneously interpreted.

Adult↗
PubMed1997

[Germ-cell tumors of the brain--their course and management].

Germ-cell tumors (GCT) of the CNS constitute a small group with an incidence varying in the range 0.1 to 3.4 per cent of all primary brain neoplasms. In the WHO classification of brain tumors they are differentiated in a separate group, and further subdivided into: germinoma, teratoma (mature, immature, malignant), embryonal carcinoma, choriocarcinoma, endodermal sinus tumor and mixed germinal tumors. Of them germinoma is the most frequently encountered (41-65 per cent of all GCT), whereas the incidence rate of mixed GCT may reach 32 per cent Mainly median structures are being involved--III ventricle (pineal region and hypothalamo-hypophyseal structures), basal ganglia, with isolated cases being described in corpus callosum, cerebellum, medulla oblongata and spinal cord. Eleven patients with a total of 13 verified GCT are presented (in one instance germinomas involving the pineal body and suprasellar region are simultaneously established). The clinical course data, results of the diagnostic examinations done (CT, brain angiography, tumor markers), treatment carried out--surgical, radio- and chemotherapy, as well as the outcome of the long-term follow-up study of patients are analyzed. Three patients have mixed GCT. It is of interest to note a case where ten years after the removal of a benign teratoma in the pineal region, germinoma in the same location is diagnosed and removed.

Adolescent↗
PubMed1997

[Practical guidelines for the management of closed spinal cord injuries].

The principles underlying the necessity of operative management in handling closed spinal cord trauma, its indications and types of operative interventions are comprehensively discussed. Under separate headings are described the peculiarities of the approach to injuries involving cervical, thoracic and lumbal segments of the vertebral column, with a summarization of currently used methods and procedures, contributing to the more complete functional recovery of the spine, preservation and creation of optimal conditions for regaining the functions of the spinal cord affected which in turn, renders easier the performing of daily living activities, precludes the development of a variety of complications in the body as a whole, and first and foremost, allows for early initiation of rehabilitation measures.

Humans↗
PubMedDate not supplied

[Hydroanencephaly].

The clinical and X-ray findings in 9 infants with total and in one infant with unilateral forms of hydroanencephaly are discussed. This rare anomaly of the central nervous system is interesting from several standpoints: study of the etiopathogenic mechanisms responsible for atrophy of the hemispheres; study of different clinical phenomena in the absence of the cerebral hemispheres; study of c.s.f. changes in the absence of cerebral parenchyma; differential diagnosis with other pathological conditions, with extreme degree of hydrocephalus in the first place, which is very important for the therapeutic approach and prognosis. Attention is focus ed on the specific features of the clinical course, computer tomography (CT), angiographic and PEG values in hydroanencephaly. The etiopathogenesis of this severe pathological condition of the central nervous system is discussed on the basis of data in the literature.

Anencephaly↗