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Biomedical subjects

S Gall

Publications and source records attributed to S Gall.

24 records · Page 2Linked to original sources
PubMed1983

Intracavitary Corynebacterium parvum for treatment of malignant effusions.

Intracavitary instillation of Corynebacterium parvum was used to treat recurrent malignant effusions in 15 patients. Eleven patients were treated for ascites, and four patients were treated for pleural effusion. Six patients (40%) had good response with no recurrence of effusions up to 3 months after treatment. Three patients responded but died before criteria for complete response could be fulfilled. Six patients were judged to have poor response, either because of death from tumor burden before evaluation could be made or because of recurrent effusions. There were no serious side effects directly attributed to intracavitary C. parvum therapy. Analysis of the results in this preliminary study suggests that patients who have had prior good response to chemotherapy, whose performance scale is adequate, whose tumor burden is not preterminal, and who have been previously treated with immunotherapy may be excellent candidates for definitive treatment of malignant effusions with intracavitary C. parvum.

Adult↗
PubMed1976

Human pregnancy-associated plasma proteins during the postpartum period.

The plasma levels of four pregnancy-associated plasma proteins (PAPP's) and pregnancy zone protein (PZP) were studied in women after delivery of a single viable infant by gel immunodiffussion methods. Data from 89 random samples and 85 serial specimens from five women revealed that both PAPP-B and HPL (PAPP-D) disappeared within a day after delivery. PAPP-A showed a rapid drop in the first 2 or 3 days post partum and became nondetectable in 4 to 6 weeks, with a half-life of 3 to 4 days. PAPP-C had a sharp decrease by the second postpartum day and was not detected 3 to 4 weeks later, with a half-life of 1 to 2 days. None of the PAPP's was detected again during the rest of the 14 postpartum weeks studied. In contrast, the PZP showed a much slower decrease or even a temporary increase during the first 2 weeks post partum; it remained readily detectable over the entire 14 weeks studied.

Blood Proteins↗
PubMedDate not supplied

Centrifugal Cytology, IV. The Prearation of fixed stained dispersions of gynecological cells.

The Centrifugal Cytology technique has been utilized to produce glutaraldehyde fixed stained dispersions of both conventional Ayre scrapes and Davis pipet (PAPette) samples. Light microscope studies of dispersions of both types of cells on conventional microscope slides indicated that both the tinctorial and morphological appearance of the cells after Papanicolaou staining was very similar to that observed with conventional smears and that the same criteria could be utilized with the Centrifugal Cytology dispersions to screen the cells for cancer as had previously been used with the smears. A preliminary study indicated that six out of six positives with no false negatives or false positives were found. The Centrifugal Cytology technique appears to have promise as a method for preparing suspension samples such as pipets of gynecologic cells. Scanning electron microscope studies reveal that the squamous epithelial cells are very thin and at least some of them are covered by a network structure.

Carcinoma, Squamous Cell↗