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Biomedical subjects

S Ganti

Publications and source records attributed to S Ganti.

7 recordsLinked to original sources

Profound primary hypothyroidism.

Profound primary hypothyroidism is described, presenting as a pituitary tumor in a 46-year-old male with hyperprolactinemia and hypogonadotropic hypogonadism. Replacement therapy with thyroxine reversed all of the patient's abnormalities.

Diagnosis, Differential↗

Specular microscopy of corneal epithelium after epikeratophakia.

We studied the characteristics of the corneal epithelium by specular microscopy in 12 eyes of 11 patients, at three, six, and 16 months after epikeratophakia surgery. We found attenuation of cells; irregular shape; decreased density; loss of differentiation into dark and light cells and into small, medium, and large cells; and poor interdigitation between adjacent cells. Corneal hypesthesia noted in these grafts may contribute to the aberrant epithelial characteristics.

Adult↗

A neodymium-YAG endolaser.

We used a CW-YAG endolaser to photocoagulate the fundus of the rabbit and monkey. We varied the power settings, exposure durations, and probe-retina distances to establish the parameters for threshold and bursting (choroidal hemorrhage) lesions. We found that the amount of energy needed to create a retinal lesion increased proportionally with the distance between the probe and the retina. To produce a choroidal hemorrhage at a given distance required at least four times the power required for a threshold coagulative lesion at the same distance. We also found that we could achieve a strong choroidal reaction without hemorrhage by using the coagulative threshold parameters of power and distance with an increased exposure time. Photocoagulation of the retina using the CW-YAG depended on the presence of melanin.

Animals↗