PubMed Health⌕ Search

Biomedical subjects

S Gaudeau

Publications and source records attributed to S Gaudeau.

At least 19 recordsLinked to original sources
PubMed1995

[Cerebral abscess disclosing tetralogy of Fallot with situs inversus in adulthood].

The authors report the case of tetralogy of Fallot (TOF) associated with situs inversus, the first description of this rare association in a previously asymptomatic adult. A 32 years old chauffeur was admitted to hospital with pyrexia and convulsions due to a left temporo-parietal cerebral abscess which had a favourable outcome. The chest X-ray and Doppler echocardiographic study showed a TOF with a high infundibular stenosis and dextrocardia. Abdominal ultrasonography confirmed a complete situs inversus. The good tolerance was attributed to the equilibrated character of the TOF. The orientation of the heart and the cono-truncal septation occur at different times during embryogenesis. However, there are genetic arguments in favour of the non-fortuitous nature of this association.

Adult↗
PubMed1991

[Valvotomy and congenital aortic valve stenosis. Long-term results].

Twenty nine patients (average age 11 years) underwent valvotomy for congenital valvular aortic stenosis from 1967 to 1983. The medium and long-term results were analysed retrospectively: 14 children have been reoperated; 11 for restenosis and 3 for aortic regurgitation after an average period of 11 years. Thirteen of the other 15 patients have been regularly followed-up for about 10 years: there are 7 good results, 3 average results and 3 restenoses. One patient was lost to follow-up after 9 years and the other patient died secondarily of a non-cardiac cause. This series was compared to a previous one of 35 cases of valvular aortic stenosis who underwent valvotomy between 1954 and 1964. There were 6 deaths in the perioperative period and 6 during follow-up (on average 11 years after surgery), including 3 sudden deaths. Eleven patients were reoperated: 2 for endocarditis, 5 for restenosis and 4 for aortic regurgitation (on average after 13 years). Three patients were lost to follow-up and there are 9 survivors who have not been reoperated (average follow-up 27 years): 5 of these patients were reexamined; there were 2 excellent results, 2 average results and 1 restenosis. These results show that conservative surgery of congenital valvular aortic stenosis is now a low risk procedure in children, but it is a palliative solution. The main problem is that of follow-up to detect restenosis because of the risk of sudden death. This follow-up is much easier since the introduction of Doppler echocardiography, eventually associated with exercise stress testing in doubtful cases.(ABSTRACT TRUNCATED AT 250 WORDS)

Adolescent↗
PubMed1983

[Myocardiopathies and tricyclic antidepressants. Apropos of 3 cases].

The authors report three cases of cardiac failure induced or aggravated by chronic tricyclic antidepressant therapy. Tricyclic antidepressants have a negative inotropic effect both when administered acutely or chronically in animals. This action is related to plasma concentrations. However, the association of chronic tricyclic antidepressant therapy and cardiac failure is rare. The implication of these drugs in the cause of cardiac failure requires: --improvement of cardiac failure on withdrawal of therapy, as observed in our three cases; --the presence of underlying cardiac disease, as was the case in our patients; --abnormally high plasma levels of the antidepressant drugs despite normal dosage, as was verified in two of our patients. The measurement of plasma concentrations of antidepressant drugs would seem to be necessary when this form of treatment is to be administered to patients predisposed to cardiac failure.

Antidepressive Agents, Tricyclic↗
PubMed1981

[Bilateral stenosis of the renal arteries with normal urography (author's transl)].

In theory, negative urographic findings in severe hypertension exclude a renovascular origin. However, when both renal arteries are dysplastic urography may remain perfectly normal even though arteriography demonstrates tight stenoses and these patients are cured by surgical treatment. In the case reported here the only clinical sign of stenotic renal arteries was a systolic murmur on auscultation of the abdomen.

Adult↗
PubMed1979

[Aneurysm of the membranous septum, left ventricular-right atrial communication and arrhythmias].

An aneurysm of the membranous part of the interventricular septum associated with a complex congenital malformation of the endocardial cushions was diagnosed in a 39 year old woman who presented with syncope. Diagnosis was made by echocardiography and confirmed by angiography. The operative findings were: a double aneurysm of the membranous septum, a left ventricular--right atrial fistula and two hemivalves attached to papillary muscles. The usfulness of echocardiography in the diagnosis of aneurysm of the membranous interventricular septum and in the follow up of ventricular septal defects from which they arise is emphasised. The pathogenesis of the arrhythmias observed (accelerated idioventricular rhythm, reciprocating tachycardias and syncope possibly related to transient heart block) is discussed.

Adult↗
PubMed1979

[Arterial pressure during exertion in patients operated on for aortic coarctation].

19 patients were studied after operation for coarctation of the aorta. The average age at operation was 13.7 years. Crafoord's operation was performed in 16 cases and in the other three an aortic patch was necessary. The average post-operative period was 4.7 years. 14 cases were classified as good results: normal femoral pulses and arterial blood pressure. The other 5 cases were considered as unsatisfactory: 2 mediocre results with normal arterial blood pressure but diminished femoral pulses and oscillometric indices; 3 poor results with hypertension at rest. On exercise with bicycle ergometry the following results were obtained: the systolic blood pressure rose in a comparable manner to that observed in normotensive individuals of the same age on exercise except in 2 cases. These two patients had an aortic patch and one had a residual intraaortic pressure gradient. The pronostic significance of these findings is not known. However the use of an aortic patch is often associated with abnormal blood pressures at rest or on exercise. The fact that the majority of patients operated for coarctation of the aorta have normal blood pressure profiles on exercise should be emphasised.

Adolescent↗
PubMed1977

Natural history of ventricular septal defect. A study involving 790 cases.

The development of 790 untreated patients affected by ventricular septal defect (VSD) has been the object of a 25-year study. Of these patients, 72% had had at least one catheterization; 13% had several. The mean observation interval is six years, and the average age at the latest data is 19.5 years. This study covers 4717 patient-years. For the entire population, the incidence rate or aortic regurgitation is 6.3% (4.3 for 1000 patient-years) and that of bacterial endocarditis is 3.7% (2.4 for 1000 patient-years). Twenty-five patients died, 15 of them between the ages of one and 39. Of the 499 cases with several clinical examinations, 71% remained stable. In 21%, changes suggesting some level of closure developed; in 7%, infundibular stenosis began to evolve and in 1% pulmonary vascular disease began to appear or became accentuated. These different rates are studied and discussed in relation to patients' age, VSD type, and various follow-up characteristics.

Adolescent↗
PubMed1976

[Congenital arteriovenous fistula between the left subclavian artery and Pirogoff's venous junction. Surgical closure].

The authors report a case of arterio-venous fistula between the left sub-clavian artery and Pirogoff's venous junction. There was no past history of trauma, and no associated cardiovascular abnormality. The hemodynamic effects were moderate. Catheterisation and supra-sigmoid aortography permitted us to localise precisely the site of the fistula. Surgical cure was simple and carried out be cervico-sternotomy. This route of approach is broad and safe, providing satisfactory control of all the vascular structures.

Adult↗
PubMed1976

[Hyperkinetic syndromes associated with hypothiaminemia and corrected by administration of vitamin B 1].

High-output states combining tachycardia, increased cardiac output and raised blood pressure are often seen in clinical practice with causes other than the classical ones (hyperthyroidism anaemia and arterio-venous fistulae). Noticing how these syndromes ressemble cardiac beri-beri, the authors looked for hypothiaminaemia in these patients. On the 25 cases studied, two were particularly interesting as there was frank hypothiaminaemia, and also as treatment with vitamin B1 corrected not only the biochemical disorder but also the clinical symptoms, and led to lessening of the trachyardia and a reduction in cardiac output and blood pressure.

Adolescent↗
PubMed1976

[A case of myocardiopathy with hypothiaminemia exacerbated by imiparmine].

The authors report a case of a lady of 45 years of age who presented with a cardiomyopathy with hypothiaminaemia which had been made considerably worse by treatment with imipramine. Once treatment with the antidepressant was stopped, her condition returned to its previous status. The very high plasma imipramine level recorded in his case is undoubtedly the reason for the cardiac toxicity. The mechanism and role of hypothiaminaemia have not far been explained logically.

Cardiomyopathies↗
PubMed1975

[Pericardial effusions and mediastinal radiotherapy. 4 cases].

The authors report 4 cases of chronic pericardial effus-ons appearing several months after high dose mediastinal irradiation for Hodgkin's disease. They describe their clinical characteristics and course. The difficulties of differential diagnosis are mentioned, in particular recurrence of malignancy and tuberculosis. They stress the reserved long term prognosis and the absence of any specific therapeutic approach. The increasing use of madiastinal radiotherapy suggests that the incidence of such manifestations will increase.

Adrenal Cortex Hormones↗
PubMed1975

[Atresia of the pulmonary artery with intact interventricular septum. Apropos of 2 cases with prolonged course].

The authors report two cases of atresia of the pulmonary outflow with an intact interventricular septum; they are remarkable for their slow progression. In one patient the pulmonary perfusion was furnished by systemic arteries, while in the other it was by way of a patent ductus arteriosus. This second patient died following an attempted bi-cavo-pulmonary anastomosis. Such slow progression, which is the exception, is only possible if there is a substantial vicarious pulmonary circulation.

Adolescent↗
PubMed1975

[Dissecting aneurysm rupturing into the pericardium in a 10-year-old child. Temporary surgical success].

Report of the case of a child in whom a marked dilatation of the ascending aorta was discovered at the age of 7 years, because of a symptomless systolic murmur, and who developed at the age of 10 a clinical picture of dissecting aneurysm. He was operated upon successfully, and was shown to have on operation a stenotic bicuspid aortic valve. There were no signs of fibrous tissue dystrophy. Death occured suddenly at the age of 14.

Aortic Valve Stenosis↗